Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N302165-10mg | 10mg | In stock | $58.90 | |
N302165-50mg | 50mg | In stock | $189.90 | |
N302165-250mg | 250mg | In stock | $855.90 | |
N302165-1g | 1g | In stock | $3,078.90 |
Potent chloride channel blocker
Synonyms | NPPB | 107254-86-4 | 5-Nitro-2-(3-phenylpropylamino)benzoic acid | 5-Nitro-2-((3-phenylpropyl)amino)benzoic acid | 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid | CHEBI:34457 | Benzoic acid,5-nitro-2-[(3-phenylpropyl)amino]- | Benzoic acid, 5-nitro-2-((3-phenylpropyl)a |
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Specifications & Purity | Moligand™, ≥97% |
Biochemical and Physiological Mechanisms | Potent chloride channel blocker (IC 50 = 80 nM). GPR35 agonist. Able to uncouple mitochondria. Active in vivo . |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR, CHANNEL BLOCKER |
Mechanism of action | Channel blocker of CaCC;Channel blocker of ClC-2;Channel blocker of ClC-7;Activator of TRPA1 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 5-nitro-2-(3-phenylpropylamino)benzoic acid |
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INCHI | InChI=1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20) |
InChi Key | WBSMIPAMAXNXFS-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)CCCNC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O |
Isomeric SMILES | C1=CC=C(C=C1)CCCNC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O |
PubChem CID | 4549 |
Molecular Weight | 300.31 |
CAS Registry No. | 107254-86-4 |
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PubChem CID | 4549 |
ChEMBL Ligand | CHEMBL1256759 |
RCSB PDB Ligand | 7TH, 7TH |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2128257 | Certificate of Analysis | Aug 13, 2024 | N302165 |
J2128258 | Certificate of Analysis | Aug 13, 2024 | N302165 |
J2128259 | Certificate of Analysis | Aug 13, 2024 | N302165 |
J2129160 | Certificate of Analysis | Aug 13, 2024 | N302165 |
G2329260 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2329263 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2329265 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2329702 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2329706 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2329710 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2331224 | Certificate of Analysis | Dec 02, 2022 | N302165 |
G2331225 | Certificate of Analysis | Dec 02, 2022 | N302165 |
Solubility | ethanol: 3 mg/mL;DMSO: 37 mg/mL;H2O: insoluble |
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Melt Point(°C) | 178-180℃ |