Click Here for 5% Off Your First Aladdin Purchase!

NS11757 , CAS No.N612398, Gating inhibitor of K Ca2.3

  • Moligand™
Item Number
N612398
Grouped product items
SKUSizeAvailabilityPrice Qty
N612398-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$572.90
N612398-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
KCa2.3 Gating inhibitor

Basic Description

Synonymscompound 39;NS-11757
GradeMoligand™
Action TypeGATING INHIBITOR
Mechanism of actionGating inhibitor of K Ca2.3

Associated Targets

KCNN1 Tchem Small conductance calcium-activated potassium channel protein 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNN3 Tchem Small conductance calcium-activated potassium channel protein 3 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNN2 Tchem Small conductance calcium-activated potassium channel protein 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-(6,7-dichloro-1,2,3,4-tetrahydronaphthalen-1-yl)-1H-1,3-benzodiazol-2-amine
INCHI InChI=1S/C17H15Cl2N3/c18-12-8-10-4-3-7-14(11(10)9-13(12)19)20-17-21-15-5-1-2-6-16(15)22-17/h1-2,5-6,8-9,14H,3-4,7H2,(H2,20,21,22)
InChi Key JHLGZRSIUIFADK-UHFFFAOYSA-N
Canonical SMILES Clc1cc2CCCC(c2cc1Cl)Nc1nc2c([nH]1)cccc2
Isomeric SMILES C1CC(C2=CC(=C(C=C2C1)Cl)Cl)NC3=NC4=CC=CC=C4N3
PubChem CID 25102784

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Sørensen US, Strøbaek D, Christophersen P, Hougaard C, Jensen ML, Nielsen EØ, Peters D, Teuber L.  (2008)  Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels..  J Med Chem,  51  (23): (7625-34).  [PMID:18998663]

Solution Calculators