NU6300 - 96%, high purity , CAS No.2070015-09-5

  • ≥96%
Item Number
N647339
Grouped product items
SKUSizeAvailabilityPrice Qty
N647339-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
N647339-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$600.90
N647339-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,800.90
N647339-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,520.90
View related series
CDK Cell Cycle/DNA Damage

Basic Description

Specifications & Purity≥96%
Biochemical and Physiological MechanismsNU6300 is a covalent, irreversible and ATP-competitive CDK2 inhibitor with an IC 50 value of 0.16 μM. NU6300 can be used for the research of eukaryotic cell cycle- and transcription-related.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

NU6300 is a covalent, irreversible and ATP-competitive CDK2 inhibitor with an IC 50 value of 0.16 μM. NU6300 can be used for the research of eukaryotic cell cycle- and transcription-related

In Vitro

NU6300 (50 μM; 0-1 hour) covalently modifies and irreversible inhibits CDK2. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: SKUT-1B cells Concentration: 50 μM Incubation Time: 0-1 hour Result: Affected retinoblastoma tumor suppressor protein (Rb) phosphorylation in SKUT-1B cells and covalently binded with CDK2.

Form:Solid

IC50& Target:CDK2

Associated Targets(Human)

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 6-(cyclohexylmethoxy)-N-(4-ethenylsulfonylphenyl)-7H-purin-2-amine
INCHI InChI=1S/C20H23N5O3S/c1-2-29(26,27)16-10-8-15(9-11-16)23-20-24-18-17(21-13-22-18)19(25-20)28-12-14-6-4-3-5-7-14/h2,8-11,13-14H,1,3-7,12H2,(H2,21,22,23,24,25)
InChi Key KGWSQGUVJUGIPF-UHFFFAOYSA-N
Canonical SMILES C=CS(=O)(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3
Isomeric SMILES C=CS(=O)(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3
PubChem CID 118704754
Molecular Weight 413.49

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : ≥ 32 mg/mL (77.39 mM)

Related Documents

Solution Calculators