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NVP-BSK805 2HCl - ≥97%, high purity , CAS No.1092499-93-8(free base)

Item Number

N129609

Grouped product items
SKU	Size	Availability	Price
N129609-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$584.90
N129609-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$859.90
N129609-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,369.90

Basic Description

Synonyms	BSK805 dihydrochloride; NVP-BSK 805 dihydrochloride;8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	NVP-BSK805 2HCl is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3 and TYK2. An inhibitor of JAK2.

JAK2 Tclin Tyrosine-protein kinase JAK2 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Molecular Weight	563.47

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Solubility	Soluble in DMSO (113 mg/mL at 25 °C), water (3 mg/mL at 25 °C), and ethanol (15 mg/mL at 25 °C).

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