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NVP-BSK805 - 10mM in DMSO, high purity , CAS No.1092499-93-8
Basic Description Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Description: IC50 Value: 0.48 ± 0.02 nM (JAK2 JH1); 0.58 ± 0.03 nM (FL JAK2 wt) [1] BSK-805, a novel substituted quinoxaline, is a potent inhibitior of JAK2(V617F) and JAK2 wild-type enzymes, BSK-805 acts in an ATP
Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase ABL inhibitor INHIBITOR ALA1862 Tyrosine-protein kinase ABL SINGLE PROTEIN Homo sapiens
Names and Identifiers IUPAC Name 4-[[2,6-difluoro-4-[3-(1-piperidin-4-ylpyrazol-4-yl)quinoxalin-5-yl]phenyl]methyl]morpholine INCHI InChI=1S/C27H28F2N6O/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20/h1-3,12-16,20,30H,4-11,17H2 InChi Key IBPVXAOOVUAOKJ-UHFFFAOYSA-N Canonical SMILES C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F Isomeric SMILES C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F PubChem CID 46398810 Molecular Weight 490.55
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