Potent, selective, reversible dipeptidyl peptidase-IV (DPP-IV) inhibitor (K i = 11 nM). Antidiabetic agent in vivo .
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Note
25mg,50mg卖完停产，不再备货Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV). NVP-DPP728 can inhibit the amide lysozyme activity of human DPP-IV with Ki of 11 nM. NVP-DPP728 inhibits the degradation of glucagon-like peptide-1 (GLP-1), thereby enhancing the release of insulin to glucose intake. NVP-DPP728 can be used in diabetes research
1.Löw K et al.. (2020) A proopiomelanocortin-derived peptide sequence enhances plasma stability of peptide drugs.. FEBS Lett, 594 (17):(2840-2866). [PMID:32506501]
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H2416187