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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N422139-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $241.90 |
P450(e.g. CYP17) Inhibitors
Specifications & Purity | 10mM in DMSO |
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Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information NVP-VID-400 NVP-VID-400 (SDZ285428) is an inhibitor of CYP51 . NVP-VID-400 (SDZ285428) inhibits T. cruzi and T. brucei with I/E 2 a (5 min) of both <1 and I/E 2 (60 min) of 9 and 35, respectively. Targets CYP51 |
ALogP | 4.574 |
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HBD Count | 1 |
Rotatable Bond | 6 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | 4-(4-chlorophenyl)-N-(2-imidazol-1-yl-2-phenylethyl)benzamide |
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INCHI | InChI=1S/C24H20ClN3O/c25-22-12-10-19(11-13-22)18-6-8-21(9-7-18)24(29)27-16-23(28-15-14-26-17-28)20-4-2-1-3-5-20/h1-15,17,23H,16H2,(H,27,29) |
InChi Key | FHHNSSGZEIVGMS-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)C(CNC(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)N4C=CN=C4 |
Isomeric SMILES | C1=CC=C(C=C1)C(CNC(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)N4C=CN=C4 |
PubChem CID | 9952928 |
Molecular Weight | 401.89 |
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DMSO(mg / mL) Max Solubility | 15 |
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DMSO(mM) Max Solubility | 37.3236457737192 |
Water(mg / mL) Max Solubility | ˂1 |