NVP-VID-400 - 10mM in DMSO, high purity , CAS No.174262-13-6

  • 10mM in DMSO
Item Number
N422139
Grouped product items
SKUSizeAvailabilityPrice Qty
N422139-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$241.90

P450(e.g. CYP17) Inhibitors

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Information

NVP-VID-400 NVP-VID-400 (SDZ285428) is an inhibitor of CYP51 . NVP-VID-400 (SDZ285428) inhibits T. cruzi and T. brucei with I/E 2 a (5 min) of both <1 and I/E 2 (60 min) of 9 and 35, respectively.

Targets

CYP51

Product Properties

ALogP4.574
HBD Count1
Rotatable Bond6

Associated Targets(Human)

CYP24A1 Tchem 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP27B1 Tchem 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP27B1 Tchem 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cyp24a1 Cytochrome P450 24A1 (20 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-(4-chlorophenyl)-N-(2-imidazol-1-yl-2-phenylethyl)benzamide
INCHI InChI=1S/C24H20ClN3O/c25-22-12-10-19(11-13-22)18-6-8-21(9-7-18)24(29)27-16-23(28-15-14-26-17-28)20-4-2-1-3-5-20/h1-15,17,23H,16H2,(H,27,29)
InChi Key FHHNSSGZEIVGMS-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C(CNC(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)N4C=CN=C4
Isomeric SMILES C1=CC=C(C=C1)C(CNC(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)N4C=CN=C4
PubChem CID 9952928
Molecular Weight 401.89

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility15
DMSO(mM) Max Solubility37.3236457737192
Water(mg / mL) Max Solubility˂1

Related Documents

Solution Calculators