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NVS-CECR2-1 - ≥98%(HPLC), high purity , CAS No.1992047-61-6, Inhibitor of CECR2 histone acetyl-lysine reader
Potent and selective CECR2 inhibitor
Basic Description Synonyms N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-indol-5-yl)pyrimidin-4-amine Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50= 47 nM). Selective for CECR2 over a panel of bromodomains.A concentration of 1 μM is recommended for use in cellular assays. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of CECR2 histone acetyl-lysine reader
Names and Identifiers IUPAC Name N-cyclopropyl-2-propylsulfonyl-6-[1-(2,2,6,6-tetramethylpiperidin-4-yl)indol-5-yl]pyrimidin-4-amine INCHI InChI=1S/C27H37N5O2S/c1-6-13-35(33,34)25-29-22(15-24(30-25)28-20-8-9-20)18-7-10-23-19(14-18)11-12-32(23)21-16-26(2,3)31-27(4,5)17-21/h7,10-12,14-15,20-21,31H,6,8-9,13,16-17H2,1-5H3,(H,28,29,30) InChi Key XVECNLUKQDKOST-UHFFFAOYSA-N Canonical SMILES CCCS(=O)(=O)C1=NC(=CC(=N1)NC2CC2)C3=CC4=C(C=C3)N(C=C4)C5CC(NC(C5)(C)C)(C)C Isomeric SMILES CCCS(=O)(=O)C1=NC(=CC(=N1)NC2CC2)C3=CC4=C(C=C3)N(C=C4)C5CC(NC(C5)(C)C)(C)C PubChem CID 117072550 MeSH Entry Terms N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethyl-4-piperidinyl)-1H-indol-5-yl)-4-pyrimidinamine;NVS-1;NVS-CECR2-1 Molecular Weight 495.68
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 49.57, Max Conc. mM: 100
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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