Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N288945-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $236.90 | |
N288945-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $977.90 |
Potent and selective CECR2 inhibitor
Specifications & Purity | Moligand™, ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | Potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50= 47 nM). Selective for CECR2 over a panel of bromodomains.A concentration of 1 μM is recommended for use in cellular assays. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of CECR2 histone acetyl-lysine reader |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-cyclopropyl-2-propylsulfonyl-6-[1-(2,2,6,6-tetramethylpiperidin-4-yl)indol-5-yl]pyrimidin-4-amine |
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INCHI | InChI=1S/C27H37N5O2S/c1-6-13-35(33,34)25-29-22(15-24(30-25)28-20-8-9-20)18-7-10-23-19(14-18)11-12-32(23)21-16-26(2,3)31-27(4,5)17-21/h7,10-12,14-15,20-21,31H,6,8-9,13,16-17H2,1-5H3,(H,28,29,30) |
InChi Key | XVECNLUKQDKOST-UHFFFAOYSA-N |
Canonical SMILES | CCCS(=O)(=O)C1=NC(=CC(=N1)NC2CC2)C3=CC4=C(C=C3)N(C=C4)C5CC(NC(C5)(C)C)(C)C |
Isomeric SMILES | CCCS(=O)(=O)C1=NC(=CC(=N1)NC2CC2)C3=CC4=C(C=C3)N(C=C4)C5CC(NC(C5)(C)C)(C)C |
PubChem CID | 117072550 |
MeSH Entry Terms | N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethyl-4-piperidinyl)-1H-indol-5-yl)-4-pyrimidinamine;NVS-1;NVS-CECR2-1 |
Molecular Weight | 495.68 |
Enter Lot Number to search for COA:
Solubility | Solvent:DMSO, Max Conc. mg/mL: 49.57, Max Conc. mM: 100 |
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RIDADR | NONHforallmodesoftransport |
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