Nylidrin Hydrochloride - 99%, high purity , CAS No.849-55-8

  • ≥99%
Item Number
N413257
Grouped product items
SKUSizeAvailabilityPrice Qty
N413257-100mg
100mg
In stock
$306.90
N413257-200mg
200mg
In stock
$423.90
N413257-500mg
500mg
In stock
$824.90

β-adrenergic receptor Selective Inhibitors | Agonists | Antagonists

Basic Description

SynonymsNylidrin hydrochloride | 849-55-8 | Buphenine hydrochloride | Nylidrin (hydrochloride) | Nylidrin HCl | Arlibide | Arlidin | Buphedrin | Dilatol | Vasiten | Buphenin hydrochloride | NSC-142004 | MLS000069387 | Dilatyl | Suprifen psb hydrochloride | SMR000058488 | 4-[1-hydroxy-2-(4-pheny
Specifications & Purity≥99%
Biochemical and Physiological MechanismsNylidrin Hydrochloride (Buphenine), a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

Nylidrin Hydrochloride (Buphenine), aβ-adrenergicagonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.


Targets

β-adrenergic receptor

Product Properties

ALogP4.112
HBD Count3
Rotatable Bond7

Associated Targets(Human)

KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPV1 Tclin Vanilloid receptor (8273 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nfo Endonuclease 4 (425 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adra1b Adrenergic receptor alpha-1 (5652 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol;hydrochloride
INCHI InChI=1S/C19H25NO2.ClH/c1-14(8-9-16-6-4-3-5-7-16)20-15(2)19(22)17-10-12-18(21)13-11-17;/h3-7,10-15,19-22H,8-9H2,1-2H3;1H
InChi Key CLJHABUMMDMAFA-UHFFFAOYSA-N
Canonical SMILES CC(CCC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O.Cl
Isomeric SMILES CC(CCC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O.Cl
PubChem CID 5702098
Molecular Weight 335.87

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
K2219528Certificate of AnalysisSep 03, 2024 N413257
K2219500Certificate of AnalysisSep 03, 2024 N413257
K2219555Certificate of AnalysisSep 20, 2022 N413257

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 67 mg/mL (199.48 mM); Ethanol: 10 mg/mL (29.77 mM); Water: 2 mg/mL (5.95 mM);
SensitivityMoisture sensitive
Water(mg / mL) Max Solubility67
Water(mM) Max Solubility199.481942418198

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H312:Harmful in contact with skin

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P362+P364:Take off contaminated clothing and wash it before reuse.

P317:Get emergency medical help.

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