H2307795Determine the necessary mass, volume, or concentration for preparing a solution.
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Basic Description
| Synonyms | o-Cresolphthalein | 596-27-0 | 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- | 3,3-Bis(4-hydroxy-3-methylphenyl)isobenzofuran-1(3H)-one | 3',3''-Dimethylphenolphthalein | 3,3-bis(4-hydroxy-3-methylphenyl)-2-benzofuran-1-one | Phenolphthalein, 3',3''-dime |
|---|---|
| Specifications & Purity | PH color range 8.2 (colorless) ~9.8 (red/purple) |
| Biochemical and Physiological Mechanisms | O-cresol phthalein is a reversible pH indicator. The kinetics of the reverse path (red-purple to colorless) is slow, which makes it an appropriate molecule to check the flow pattern in corrugated wall tubes. It is also used for colorimetric determination |
| Storage Temp | Desiccated |
| Shipped In | Normal |
| Product Description | Soluble in ethanol, ether and glacial acetic acid, purple in dilute alkali, slightly soluble in water and hardly soluble in benzene. |
Associated Targets(Human)
POLB Tchem DNA polymerase beta (0 Activities)
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
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GMNN Tbio Geminin (0 Activities)
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POLH Tchem DNA polymerase eta (0 Activities)
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RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (0 Activities)
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KMT2A Tchem Histone-lysine N-methyltransferase 2A (0 Activities)
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SMN1 Tchem Survival motor neuron protein (0 Activities)
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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (0 Activities)
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POLI Tchem DNA polymerase iota (0 Activities)
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L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (0 Activities)
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LMNA Tbio Prelamin-A/C (0 Activities)
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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (0 Activities)
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
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MAPT Tclin Microtubule-associated protein tau (0 Activities)
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GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)
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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)
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KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)
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POLB Tchem DNA polymerase beta (23632 Activities)
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GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
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POLI Tchem DNA polymerase iota (116820 Activities)
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POLH Tchem DNA polymerase eta (21678 Activities)
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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
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L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
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SMN1 Tchem Survival motor neuron protein (34246 Activities)
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LMNA Tbio Prelamin-A/C (36751 Activities)
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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
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GMNN Tbio Geminin (128009 Activities)
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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
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RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)
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Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
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TGR Thioredoxin glutathione reductase (28579 Activities)
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Mapt Microtubule-associated protein tau (6 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 3,3-bis(4-hydroxy-3-methylphenyl)-2-benzofuran-1-one |
|---|---|
| INCHI | InChI=1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3 |
| InChi Key | CPBJMKMKNCRKQB-UHFFFAOYSA-N |
| Canonical SMILES | CC1=C(C=CC(=C1)C2(C3=CC=CC=C3C(=O)O2)C4=CC(=C(C=C4)O)C)O |
| Isomeric SMILES | CC1=C(C=CC(=C1)C2(C3=CC=CC=C3C(=O)O2)C4=CC(=C(C=C4)O)C)O |
| WGK Germany | 3 |
| PubChem CID | 68995 |
| Molecular Weight | 346.38 |
| Beilstein | 310554 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Melt Point(°C) | 223-225°C |
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Safety and Hazards(GHS)
| WGK Germany | 3 |
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Related Documents
Citations of This Product
| 1. Fan Yang, Hongbo Yu, Chunzheng Wu, Shiwei Wang, Tong Li, Hongfeng Yin. (2022) RhCu Bimetallic Nanoparticles in Hollow Carbon Spheres for Catalytic Halonitrobenzene Chemoselective Hydrogenation. ACS Applied Nano Materials, 5 (8): (11627–11635). [PMID:] [10.1021/acsanm.2c02358] |
| 2. Yongmei Tang, Lan Li, Kai Ma, Guofei Chen, Wei Wang, Xingzhong Fang. (2018) Transparent and organosoluble cardo polyimides with different trans/cis ratios of 1,4-diaminocyclohexane via aromatic nucleophilic substitution polymerization. POLYMER INTERNATIONAL, 67 (5): (598-605). [PMID:] [10.1002/pi.5556] |
| 3. Nafeesa Mushtaq, Lala Rukh Sidra, Guofei Chen, Yongmei Tang, Lubo Xu, Xingzhong Fang. (2017) Synthesis of cardo containing asymmetric poly(ether-naphthalimide-phthalimide)s. POLYMER INTERNATIONAL, 66 (11): (1633-1639). [PMID:] [10.1002/pi.5425] |
| 4. Leiduan Hao, Yanfei Zhao, Bo Yu, Hongye Zhang, Huanjun Xu, Jilei Xu, Zhimin Liu. (2014) Polyurea-supported metal nanocatalysts: Synthesis, characterization and application in selective hydrogenation of o-chloronitrobenzene. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 424 (44). [PMID:24767496] [10.1016/j.jcis.2014.03.015] |
References
| 1. Fan Yang, Hongbo Yu, Chunzheng Wu, Shiwei Wang, Tong Li, Hongfeng Yin. (2022) RhCu Bimetallic Nanoparticles in Hollow Carbon Spheres for Catalytic Halonitrobenzene Chemoselective Hydrogenation. ACS Applied Nano Materials, 5 (8): (11627–11635). [PMID:] [10.1021/acsanm.2c02358] |
| 2. Yongmei Tang, Lan Li, Kai Ma, Guofei Chen, Wei Wang, Xingzhong Fang. (2018) Transparent and organosoluble cardo polyimides with different trans/cis ratios of 1,4-diaminocyclohexane via aromatic nucleophilic substitution polymerization. POLYMER INTERNATIONAL, 67 (5): (598-605). [PMID:] [10.1002/pi.5556] |
| 3. Nafeesa Mushtaq, Lala Rukh Sidra, Guofei Chen, Yongmei Tang, Lubo Xu, Xingzhong Fang. (2017) Synthesis of cardo containing asymmetric poly(ether-naphthalimide-phthalimide)s. POLYMER INTERNATIONAL, 66 (11): (1633-1639). [PMID:] [10.1002/pi.5425] |
| 4. Leiduan Hao, Yanfei Zhao, Bo Yu, Hongye Zhang, Huanjun Xu, Jilei Xu, Zhimin Liu. (2014) Polyurea-supported metal nanocatalysts: Synthesis, characterization and application in selective hydrogenation of o-chloronitrobenzene. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 424 (44). [PMID:24767496] [10.1016/j.jcis.2014.03.015] |