O4I2 - ≥98%(HPLC), high purity , CAS No.165682-93-9

  • ≥98%(HPLC)
Item Number
O286975
Grouped product items
SKUSizeAvailabilityPrice Qty
O286975-5mg
5mg
In stock
$58.90
O286975-10mg
10mg
In stock
$78.90
O286975-25mg
25mg
In stock
$177.90
O286975-50mg
50mg
In stock
$246.90
O286975-100mg
100mg
In stock
$444.90
O286975-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,001.90

Oct3/4 inducer; induces expression of pluripotent-associated genes

Basic Description

SynonymsO4I2 | 165682-93-9 | ETHYL 2-(4-CHLOROPHENYLAMINO)-4-THIAZOLECARBOXYLATE | Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate | ethyl 2-(4-chloroanilino)-1,3-thiazole-4-carboxylate | ethyl 2-[(4-chlorophenyl)amino]-1,3-thiazole-4-carboxylate | 4-Thiazolecarboxylic
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsOct3/4 inducer; promotesOct3/4expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genesLin28,Sox2andNanog, and suppressesRex1. Induces 15-fold increase inOct3/4expression in human primary fibroblasts.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POU5F1 Tbio POU domain, class 5, transcription factor 1 (69 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name ethyl 2-(4-chloroanilino)-1,3-thiazole-4-carboxylate
INCHI InChI=1S/C12H11ClN2O2S/c1-2-17-11(16)10-7-18-12(15-10)14-9-5-3-8(13)4-6-9/h3-7H,2H2,1H3,(H,14,15)
InChi Key ULUBAPWNHROTEU-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)C1=CSC(=N1)NC2=CC=C(C=C2)Cl
Isomeric SMILES CCOC(=O)C1=CSC(=N1)NC2=CC=C(C=C2)Cl
PubChem CID 53428670
Molecular Weight 282.75

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
F2204966Certificate of AnalysisFeb 15, 2022 O286975
F2204982Certificate of AnalysisFeb 15, 2022 O286975
F2204983Certificate of AnalysisFeb 15, 2022 O286975
F2204984Certificate of AnalysisFeb 15, 2022 O286975
F2204985Certificate of AnalysisFeb 15, 2022 O286975
F2204986Certificate of AnalysisFeb 15, 2022 O286975

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 28.27, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 14.14, Max Conc. mM: 50

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H312:Harmful in contact with skin

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RIDADR NONHforallmodesoftransport

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