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O8 OGG1 Inhibitor - 10mM in DMSO, high purity , CAS No.350997-39-6
Potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor
Basic Description Synonyms 3,4-dichloro-1-benzothiophene-2-carbohydrazide | 350997-39-6 | O8 OGG1 Inhibitor | 3,4-dichlorobenzo[b]thiophene-2-carbohydrazide | OGG1-IN-O8 | OGG1 inhibitor O8 | OGG1-IN-08 | 3,4-Dichloro-benzo[b]thiophene-2-carboxylic acid hydrazide | CBMicro_031749 | Cambridge id 6132 Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor (IC50= 0.2 μM in a gel based assay). Exhibits > 200-fold selectivity for OGG1 over other DNA glycosylases, NEIL1 and NTH1. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 3,4-dichloro-1-benzothiophene-2-carbohydrazide INCHI InChI=1S/C9H6Cl2N2OS/c10-4-2-1-3-5-6(4)7(11)8(15-5)9(14)13-12/h1-3H,12H2,(H,13,14) InChi Key HSSHUDKWJRJKPV-UHFFFAOYSA-N Canonical SMILES C1=CC2=C(C(=C1)Cl)C(=C(S2)C(=O)NN)Cl Isomeric SMILES C1=CC2=C(C(=C1)Cl)C(=C(S2)C(=O)NN)Cl PubChem CID 874733 Molecular Weight 261.13
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