OB 24 hydrochloride - ≥98%(HPLC), high purity , CAS No.939825-12-4

Item Number

O287680

• Synonyms: SCHEMBL407935 | UNII-B2FQJ9RF5L | 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride | 1H-Imidazole, 1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-, hydrochloride (1:1) | 2-(2-(4-Bromophenyl)ethyl)-2-((1H-imidaz
• Specifications & Purity: ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferatio
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads

Product Description

OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA).