OB 24 hydrochloride - ≥98%(HPLC), high purity , CAS No.939825-12-4

Item Number

O287680

Grouped product items
SKU	Size	Availability	Price
O287680-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$374.90
O287680-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$599.90
O287680-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,099.90
O287680-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,699.90

Potent and selective heme oxygenase 1 (HO-1) inhibitor

Basic Description

Synonyms	939825-12-4 \| OB 24 hydrochloride \| OB-24 \| OB-24 HCl \| OB24Hydrochloride \| OB-24 hydrochloride \| B2FQJ9RF5L \| 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride \| CHEMBL539857 \| 1-((2-(4-Bromophenethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazo
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferatio
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA).

Associated Targets(Human)

HMOX2 Tchem Heme oxygenase 2 (250 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HMOX1 Tchem Heme oxygenase 1 (32 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	1-[[2-[2-(4-bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride
INCHI	InChI=1S/C15H17BrN2O2.ClH/c16-14-3-1-13(2-4-14)5-6-15(19-9-10-20-15)11-18-8-7-17-12-18;/h1-4,7-8,12H,5-6,9-11H2;1H
InChi Key	YSOWYXRHOAXXTG-UHFFFAOYSA-N
Canonical SMILES	C1COC(O1)(CCC2=CC=C(C=C2)Br)CN3C=CN=C3.Cl
Isomeric SMILES	C1COC(O1)(CCC2=CC=C(C=C2)Br)CN3C=CN=C3.Cl
PubChem CID	45265865
Molecular Weight	373.67

Certificates

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot Number	Certificate Type	Date	Item
D2419512	Certificate of Analysis	Feb 01, 2024	O287680
D2419513	Certificate of Analysis	Feb 01, 2024	O287680
D2419514	Certificate of Analysis	Feb 01, 2024	O287680
D2419515	Certificate of Analysis	Feb 01, 2024	O287680
D2419516	Certificate of Analysis	Feb 01, 2024	O287680
D2419517	Certificate of Analysis	Feb 01, 2024	O287680
D2419548	Certificate of Analysis	Feb 01, 2024	O287680
D2419549	Certificate of Analysis	Feb 01, 2024	O287680

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description