OBAA - 98%, high purity , CAS No.221632-26-4

  • ≥98%
Item Number
O288799
Grouped product items
SKUSizeAvailabilityPrice Qty
O288799-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$23.90
O288799-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
O288799-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$137.90
O288799-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
O288799-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$578.90

Phospholipase A2inhibitor

Basic Description

SynonymsIDI1_002087 | (2E)-4-(4-Octadecylphenyl)-4-oxo-2-butenoic acid | BCBcMAP01_000119 | HMS1990B05 | BDBM50604040 | NCGC00024680-03 | HMS1792B05 | MS-27599 | NCGC00024680-02 | DTXSID10874032 | SR-01000597619 | HMS1362B05 | OBAA | AKOS015914337 | CHEBI:92834 |
Specifications & Purity≥98%
Biochemical and Physiological MechanismsA potent inhibitor of phospholipase A2(IC50= 70 nM). Reduces bronchospasm in guinea pigsin vivo.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

OBAA is a potent phospholipase A2 (PLA2) inhibitor with an IC50 of 70 nM. OBAA blocks Melittin-induced Ca2+ influx in Trypanosoma brucei with an IC50 of 0.4 μM。

Associated Targets(Human)

VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP (8286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATG4B Tchem Cysteine protease ATG4B (985 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PLA2G1B Phospholipase A2 group 1B (227 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (E)-4-(4-octadecylphenyl)-4-oxobut-2-enoic acid
INCHI InChI=1S/C28H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-19-21-26(22-20-25)27(29)23-24-28(30)31/h19-24H,2-18H2,1H3,(H,30,31)/b24-23+
InChi Key ZBESASFHIWDSCJ-WCWDXBQESA-N
Canonical SMILES CCCCCCCCCCCCCCCCCCC1=CC=C(C=C1)C(=O)C=CC(=O)O
Isomeric SMILES CCCCCCCCCCCCCCCCCCC1=CC=C(C=C1)C(=O)/C=C/C(=O)O
PubChem CID 5353842
Molecular Weight 428.65

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
H2413160Certificate of AnalysisApr 19, 2024 O288799
H2413161Certificate of AnalysisApr 19, 2024 O288799
H2413162Certificate of AnalysisApr 19, 2024 O288799
H2413163Certificate of AnalysisApr 19, 2024 O288799
H2413164Certificate of AnalysisApr 19, 2024 O288799
H2413165Certificate of AnalysisApr 19, 2024 O288799
H2413258Certificate of AnalysisApr 19, 2024 O288799
H2413259Certificate of AnalysisApr 19, 2024 O288799
H2413260Certificate of AnalysisApr 19, 2024 O288799
H2413261Certificate of AnalysisApr 19, 2024 O288799

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 4.29, Max Conc. mM: 10 with gentle warming

Related Documents

Solution Calculators