OG-L002 - ≥98%(HPLC), high purity , CAS No.1357302-64-7, Inhibitor of lysine demethylase 1A

Item Number
O288423
Grouped product items
SKUSizeAvailabilityPrice Qty
O288423-5mg
5mg
In stock
$122.90
O288423-10mg
10mg
In stock
$211.90
O288423-25mg
25mg
In stock
$477.90
O288423-50mg
50mg
In stock
$637.90
O288423-100mg
100mg
In stock
$1,148.90

Potent LSD1 inhibitor

Basic Description

Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsPotent LSD1 inhibitor (IC50= 20 nM). Exhibits some selectivity for LSD1 over MAO-B and MAO-A (IC50values are 0.72 and 1.38 μM, respectively). Inhibits herpes simplex virus (HSV) immediate early gene expression and viral yieldin vitro. Suppresses HSV prima
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of lysine demethylase 1A

Associated Targets(Human)

KDM1A Tchem Lysine-specific histone demethylase 1A (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM1A Tchem Lysine-specific histone demethylase 1 (3916 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Schistosoma mansoni (6170 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol
INCHI InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1
InChi Key DSOJSZXQRJGBCW-CABCVRRESA-N
Canonical SMILES C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O
Isomeric SMILES C1[C@@H]([C@H]1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O
PubChem CID 56639570
Molecular Weight 225.29

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
K2222591Certificate of AnalysisMar 09, 2022 O288423
K2222598Certificate of AnalysisMar 09, 2022 O288423
K2222604Certificate of AnalysisMar 09, 2022 O288423
K2222605Certificate of AnalysisMar 09, 2022 O288423
K2222607Certificate of AnalysisMar 09, 2022 O288423

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 22.53, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 22.53, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 4.51, Max Conc. mM: 20

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