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Ogerin - ≥98%(HPLC), high purity , CAS No.1309198-71-7, Allosteric modulator of GPR68
Selective positive allosteric modulator at GPR68
Basic Description Synonyms 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Selective positive allosteric modulator at GPR68 (pEC50= 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ALLOSTERIC MODULATOR Mechanism of action Allosteric modulator of GPR68
Names and Identifiers IUPAC Name [2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl]methanol INCHI InChI=1S/C17H17N5O/c18-16-20-15(14-9-5-4-8-13(14)11-23)21-17(22-16)19-10-12-6-2-1-3-7-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) InChi Key MDGIEDNDSFMSLP-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)CNC2=NC(=NC(=N2)N)C3=CC=CC=C3CO Isomeric SMILES C1=CC=C(C=C1)CNC2=NC(=NC(=N2)N)C3=CC=CC=C3CO PubChem CID 56707820 MeSH Entry Terms ogerin;ZINC67740571 Molecular Weight 307.35
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 30.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.15, Max Conc. mM: 20
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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