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OL135 , CAS No.681135-77-3, Inhibitor of Fatty acid amide hydrolase;Inhibitor of Fatty acid amide hydrolase-2
Basic Description
| Synonyms | OL-135 | 681135-77-3 | OL135 | NC2J8K4ARH | CHEMBL177577 | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptan-1-one | 1-oxo-1-[5-(2-pyridyl)oxazol-2-yl]-7-phenylheptane | 1-Oxo-1-(5-(2-pyridyl)oxazol-2-yl)-7-phenylheptane | 7-Phenyl-1-(5-(2-pyridinyl)-2-oxazolyl)-1-hept |
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| Specifications & Purity | Moligand™ |
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| Grade | Moligand™ |
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| Action Type | INHIBITOR |
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| Mechanism of action | Inhibitor of Fatty acid amide hydrolase;Inhibitor of Fatty acid amide hydrolase-2 |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 7-phenyl-1-(5-pyridin-2-yl-1,3-oxazol-2-yl)heptan-1-one |
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| INCHI | InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 |
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| InChi Key | ILOIOIGZFHGSMS-UHFFFAOYSA-N |
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| Canonical SMILES | C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=CC=CC=N3 |
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| Isomeric SMILES | C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=CC=CC=N3 |
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| WGK Germany | 3 |
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| PubChem CID | 10427006 |
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| Molecular Weight | 334.41 |
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Safety and Hazards(GHS)
| Hazard Statements | H413:May cause long lasting harmful effects to aquatic life |
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| WGK Germany | 3 |
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| RIDADR | NONHforallmodesoftransport |
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References
| 1. Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF. (2006) A second fatty acid amide hydrolase with variable distribution among placental mammals.. J Biol Chem, 281 (48): (36569-78). [PMID:17015445] [10.1021/op500134e] |
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