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OLDA - 96%, high purity , CAS No.105955-11-1, Agonist of GPR119
Potent and selective endogenous TRPV1 agonist
Basic Description
| Synonyms | N-Oleoyldopamine|OLDA|N-Oleoyl dopamine|105955-11-1|N-oleoyl-dopamine|OLEOYL DOPAMINE|UNII-T87P7X9XSZ|T87P7X9XSZ|CHEBI:31883|N-[2-(3,4-dihydroxyphenyl)ethyl]-9Z-octadecenamide|(Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]octadec-9-enamide|N-(9Z-octadecanoyl)-dopam |
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| Specifications & Purity | Moligand™, ≥96% |
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| Biochemical and Physiological Mechanisms | Potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50= 36 nM at hVR1) with low affinity for rCB1receptors (Ki= 1.6μM). Potently induces VR1-mediated thermal hyperalgesia in ratsin vivo. |
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| Storage Temp | Store at -20°C,Desiccated |
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| Shipped In | Ice chest + Ice pads |
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| Grade | Moligand™ |
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| Action Type | AGONIST |
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| Mechanism of action | Agonist of GPR119 |
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Names and Identifiers
| IUPAC Name | (Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]octadec-9-enamide |
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| INCHI | InChI=1S/C26H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(30)27-21-20-23-18-19-24(28)25(29)22-23/h9-10,18-19,22,28-29H,2-8,11-17,20-21H2,1H3,(H,27,30)/b10-9- |
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| InChi Key | QQBPLXNESPTPNU-KTKRTIGZSA-N |
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| Canonical SMILES | CCCCCCCCC=CCCCCCCCC(=O)NCCC1=CC(=C(C=C1)O)O |
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| Isomeric SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)NCCC1=CC(=C(C=C1)O)O |
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| PubChem CID | 5282106 |
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| Molecular Weight | 417.63 |
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Chemical and Physical Properties
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 20.88, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 20.88, Max Conc. mM: 50 |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
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