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opiranserin , CAS No.1441000-45-8, Inhibitor of GlyT2

CAS#: 1441000-45-8
PubChem CID: 71566778

Item Number

O612541

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SKU	Size	Availability	Price	Qty
O612541-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$315.90
O612541-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,101.90

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GlyT2 Inhibitor

Basic Description

Synonyms	Opiranserin \| 1441000-45-8 \| VVZ-149 free base \| AP031EC2NI \| CHEMBL4228903 \| 4-butoxy-N-[[4-(dimethylamino)oxan-4-yl]methyl]-3,5-dimethoxybenzamide \| 4-Butoxy-N-((4-(dimethylamino)tetrahydro-2H-pyran-4-yl)methyl)-3,5-dimethoxybenzamide \| 4-Butoxy-N-((4-(dimethylamino)
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of GlyT2

Associated Targets(Human)

SLC6A5 Tchem Sodium- and chloride-dependent glycine transporter 2 (1 Activities)

Discover Target: SLC6A5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

Discover Target: HTR2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A5 Tchem Glycine transporter 2 (697 Activities)

Discover Target: SLC6A5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

INCHI	InChI=1S/C21H34N2O5/c1-6-7-10-28-19-17(25-4)13-16(14-18(19)26-5)20(24)22-15-21(23(2)3)8-11-27-12-9-21/h13-14H,6-12,15H2,1-5H3,(H,22,24)
InChi Key	JQUVQWMHZSYCRQ-UHFFFAOYSA-N
Canonical SMILES	CCCCOc1c(OC)cc(cc1OC)C(=O)NCC1(CCOCC1)N(C)C
Isomeric SMILES	CCCCOC1=C(C=C(C=C1OC)C(=O)NCC2(CCOCC2)N(C)C)OC
PubChem CID	71566778

PubChem CID

ChEMBL Ligand

CAS Registry No.

BindingDB Ligand

References

1. Oh J, Lee S, Kim A, Yoon J, Jang K, Lee DH, Cho S, Lee SR, Yu KS, Chung JY. (2018) Safety, Tolerability, and Pharmacokinetic Characteristics of a Novel Nonopioid Analgesic, VVZ-149 Injections in Healthy Volunteers: A First-in-Class, First-in-Human Study.. J Clin Pharmacol, 58 (1): (64-73). [PMID:28815639]

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opiranserin , CAS No.1441000-45-8, Inhibitor of GlyT2

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

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