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Org 27569 - ≥98%, high purity , CAS No.868273-06-7, Allosteric modulator of CB 1 receptor

Specifications & Purity: ≥98%

CAS#: 868273-06-7
Formula: C₂₄H₂₈ClN₃O
Molecular Weight: 409.95
EC Number: 278-169-7
MDL number: MFCD11045300
PubChem CID: 44828492

Item Number

O129837

Grouped product items
SKU	Size	Availability	Price	Qty
O129837-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$98.90
O129837-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$355.90

Potent CB 1 receptor allosteric modulator

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CB1 receptor Allosteric modulator

Basic Description

Synonyms	Org 27569\|868273-06-7\|Org27569\|ORG-27569\|5-Chloro-3-ethyl-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide\|ab120342\|7YW2S3Z2CB\|CHEMBL1553629\|5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide\|5-chloro-3-ethyl-N-{2-[4-(pipe
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of CB 1 receptor

Names and Identifiers

IUPAC Name	5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
INCHI	InChI=1S/C24H28ClN3O/c1-2-20-21-16-18(25)8-11-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28/h6-11,16,27H,2-5,12-15H2,1H3,(H,26,29)
InChi Key	AHFZDNYNXFMRFQ-UHFFFAOYSA-N
Canonical SMILES	CCC1=C(NC2=C1C=C(C=C2)Cl)C(=O)NCCC3=CC=C(C=C3)N4CCCCC4
Isomeric SMILES	CCC1=C(NC2=C1C=C(C=C2)Cl)C(=O)NCCC3=CC=C(C=C3)N4CCCCC4
PubChem CID	44828492
Molecular Weight	409.95

ChEMBL Ligand

PubChem CID

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Lot Number	Certificate Type	Date	Item
F1525078	Certificate of Analysis	Jan 24, 2023	O129837

Solubility

Soluble to 100 mM in DMSO

Sensitivity

Moisture sensitive

References

1. Price MR, Baillie GL, Thomas A, Stevenson LA, Easson M, Goodwin R, McLean A, McIntosh L, Goodwin G, Walker G et al.. (2005) Allosteric modulation of the cannabinoid CB1 receptor.. Mol Pharmacol, 68 (5): (1484-95). [PMID:16113085]
2. Fay JF, Farrens DL. (2012) A key agonist-induced conformational change in the cannabinoid receptor CB1 is blocked by the allosteric ligand Org 27569.. J Biol Chem, 287 (40): (33873-82). [PMID:22846992]

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Org 27569 - ≥98%, high purity , CAS No.868273-06-7, Allosteric modulator of CB 1 receptor

Basic Description

Associated Targets

CNR1 Tclin Cannabinoid receptor 1 5 Activities

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Chemical and Physical Properties

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