orphenadrine , CAS No.83-98-7

Item Number

O612556

Grouped product items
SKU	Size	Availability	Price
O612556-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$49.90
O612556-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$64.90
O612556-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$104.90
O612556-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
O612556-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$224.90

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Basic Description

Synonyms	orphenadrine\|Orphenadrin\|Orphenadine\|83-98-7\|o-Methyldiphenhydramine\|Disipal\|Orphenedrine\|2-Methyldiphenhydramine\|Mefenamine\|Orfenadrina\|Orphenadinum\|Orphenadrinum\|Brocadisipal\|o-Monomethyldiphenhydramine\|Invagesic\|2-(Phenyl-o-tolylmethoxy)ethyldimethylam
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Orphenadrine ((±)-Orphenadrine) is a skeletal muscle relaxant and NMDA antagonist . Orphenadrine inhibits the binding of [3H]MK-801 to the phencyclidine (PCP) binding site of the NMDA receptor. Orphenadrine is also an anticholinergic and cytochrome P450 (CYP) 2B inducer. Orphenadrine may exert pro-tumor effects, causing CAR nuclear translocation, resulting in microsomal reactive oxygen species (ROS) production and oxidative stress. Orphenadrine also exerts neuronal protection, protecting rat cerebellar granule cells (CGC) from 3-NPA-induced death and has inhibitory potential against neurodegenerative diseases mediated by NMDA receptor overactivation .

Names and Identifiers

IUPAC Name	dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine
INCHI	InChI=1S/C18H23NO/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16/h4-12,18H,13-14H2,1-3H3
InChi Key	QVYRGXJJSLMXQH-UHFFFAOYSA-N
Canonical SMILES	CN(CCOC(c1ccccc1C)c1ccccc1)C
Isomeric SMILES	CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C
PubChem CID	4601
Molecular Weight	269.38