OUL35 - ≥98%(HPLC), high purity , CAS No.6336-34-1

  • ≥98%(HPLC)
Item Number
O288317
Grouped product items
SKUSizeAvailabilityPrice Qty
O288317-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$64.90
O288317-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$107.90
O288317-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$216.90
O288317-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$347.90
O288317-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$543.90
O288317-200mg
200mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$979.90

Selective PARP-10 inhibitor

Basic Description

SynonymsNSC39047 | HMS2754A23 | OUL 35 | NSC39047 | NSC-39047 | SR-01000391101-1 | AKOS001482413 | DTXSID10284793 | SCHEMBL3137816 | HMS1415F19 | SMR000393949 | 4-(4-carbamoylphenoxy)benzamide | 4,4'-oxydibenzamide | 4-(4-aminocarbonylphenoxy)benzamide | MS-23611
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsSelective PARP-10 (also known as ADP-ribosyltransferase Diptheria Toxin-like 10, ARTD10) inhibitor (IC50= 0.329 μM). Displays selectivity for PARP-10 over a panel of PARP family members. Rescues HeLa cells from PARP-10-induced cell death. Sensitizes cance
Storage TempStore at 2-8°C,Protected from light
Shipped InWet ice

Associated Targets(Human)

PARP10 Tchem Poly [ADP-ribose] polymerase 10 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP1 Tclin Poly [ADP-ribose] polymerase-1 (6206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP2 Tclin Poly [ADP-ribose] polymerase 2 (1185 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP3 Tclin Poly [ADP-ribose] polymerase 3 (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNKS Tchem Tankyrase-1 (1241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP4 Tchem Poly [ADP-ribose] polymerase 4 (71 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNKS2 Tchem Tankyrase-2 (1531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP14 Tchem Poly [ADP-ribose] polymerase 14 (380 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP15 Tchem Poly [ADP-ribose] polymerase 15 (178 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP11 Tbio Poly [ADP-ribose] polymerase 11 (83 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP10 Tchem Poly [ADP-ribose] polymerase 10 (418 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP12 Tchem Poly [ADP-ribose] polymerase 12 (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PARP16 Tchem Mono [ADP-ribose] polymerase PARP16 (46 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ZC3HAV1 Tbio Zinc finger CCCH-type antiviral protein 1 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-(4-carbamoylphenoxy)benzamide
INCHI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)
InChi Key XZRCQWLPMXFGHE-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)N
Isomeric SMILES C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)N
PubChem CID 236501
Molecular Weight 256.26

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
D2317034Certificate of AnalysisMar 10, 2023 O288317
D2317035Certificate of AnalysisMar 10, 2023 O288317
D2317046Certificate of AnalysisMar 10, 2023 O288317
D2317060Certificate of AnalysisMar 10, 2023 O288317
D2317072Certificate of AnalysisMar 10, 2023 O288317
D2317073Certificate of AnalysisMar 10, 2023 O288317

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 25.63, Max Conc. mM: 100
SensitivityLight sensitive

Safety and Hazards(GHS)

RIDADR NONHforallmodesoftransport

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Solution Calculators