Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | oxalacetic acid | oxaloacetic acid | 328-42-7 | 2-Oxobutanedioic acid | 2-Oxosuccinic acid | oxaloacetate | Ketosuccinic acid | Oxosuccinic acid | 2-Ketosuccinic acid | Butanedioic acid, oxo- | Oxobutanedioic acid | Oxalacetic acetic | 2-oxo-butanedioic acid | Bioepg | Butanedioic a |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Oxaloacetic acid is an intermediate in the TCA Cycle.Oxaloacetic acid being an intermediate in the tri carboxylic cycle is central to metabolism. It is part of gluconeogenesis pathway. Mutation in pyruvate carboxylase leads to decreased production of oxal |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | Oxaloacetic Acid substrate for malate dehydrogenase and oxaloacetate decarboxylase. Oxaloacetic Acid is an inhibitor of SDH.Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid. |
Associated Targets(Human)
SLC22A7 Tbio Solute carrier family 22 member 7 (0 Activities)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KDM5B Tchem Lysine-specific demethylase 5B (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SLC22A7 Tbio Solute carrier family 22 member 7 (39 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KDM5B Tchem Lysine-specific demethylase 5B (814 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
A085R Prolyl 4-hydroxylase (72 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
citA Putative citrate synthase 2 (14 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Names and Identifiers
| IUPAC Name | 2-oxobutanedioic acid |
|---|---|
| INCHI | InChI=1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9) |
| InChi Key | KHPXUQMNIQBQEV-UHFFFAOYSA-N |
| Canonical SMILES | C(C(=O)C(=O)O)C(=O)O |
| Isomeric SMILES | C(C(=O)C(=O)O)C(=O)O |
| WGK Germany | 3 |
| PubChem CID | 970 |
| UN Number | 3261 |
| Molecular Weight | 132.07 |
| Beilstein | 1705475 |
| Reaxy-Rn | 1705475 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | heat sensitive |
|---|---|
| Refractive Index | 1.5 |
| Boil Point(°C) | 341.9 °C |
| Melt Point(°C) | 161°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H319:Causes serious eye irritation H314:Causes severe skin burns and eye damage |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P337+P317:If eye irritation persists: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. |
| WGK Germany | 3 |
| Reaxy-Rn | 1705475 |
| Merck Index | 6909 |