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Oxaprozin - ≥98%, high purity , Cyclooxygenase inhibitor, CAS No.21256-18-8, Cyclooxygenase inhibitor
Basic Description Synonyms oxaprozin|21256-18-8|Daypro|3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid|Alvo|3-(4,5-Diphenyloxazol-2-yl)propanoic acid|Oxaprozinum|Oxaprozine|Deflam|Voir|Oxaprozina|4,5-Diphenyl-2-oxazolepropionic acid|WY-21743|4,5-Diphenyl-2-oxazolepropanoic acid|WY-2 Specifications & Purity Moligand™, ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Cyclooxygenase inhibitor Product Description Product Introduction
Oxaprozin is a non-steroidal anti-inflammatory drug prescribed for rheumatoid arthritis (RA) and osteoarthritis (OA). Oxaprozin binds to albumin. It inhibits arachidonic acid pathway. Oxaprozin has anti-inflammatory property and is an effective inhibitor of cyclooxygenase enzymes, COX-1 and COX-2.
Application
Anti-inflammatory
Names and Identifiers IUPAC Name 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid INCHI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21) InChi Key OFPXSFXSNFPTHF-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3 Isomeric SMILES C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3 WGK Germany 3 RTECS HP3090000 PubChem CID 4614 Molecular Weight 293.32 Reaxy-Rn 1083168
Chemical and Physical Properties Solubility Soluble in water (8.8 mg/L) at 25 °C, DMSO, and methanol. Melt Point(°C) 163 °C
Safety and Hazards(GHS) Pictogram(s) GHS09 , GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H411: Toxic to aquatic life with long lasting effects
H412: Harmful to aquatic life with long lasting effects
H413: May cause long lasting harmful effects to aquatic life
H302: Harmful if swallowed
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P362+P364: Take off contaminated clothing and wash it before reuse.
P391: Collect spillage.
P330: Rinse mouth.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P317: IF SWALLOWED: Get medical help.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
WGK Germany 3 RTECS HP3090000 Reaxy-Rn 1083168 Merck Index 6924
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