Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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O129611-5g | 5g | In stock | $91.90 | |
O129611-25g | 25g | In stock | $228.90 | |
O129611-100g | 100g | In stock | $820.90 | |
O129611-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,693.90 |
Synonyms | GTPL7252 | Lopac-O-9637 | SPBio_002940 | 3-(diphenyl-1,3-oxazol-2-yl)propanoic acid | Wy21743 | WY-21743 | BIDD:PXR0149 | M01AE12 | HMS1571C22 | Lopac0_000944 | Oxaprozinum | 4,5-Diphenyl-2-oxazolepropanoic acid | MLS001424072 | oxaprosin | Spectrum4_0012 |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Cyclooxygenase inhibitor |
Product Description | Product Introduction Oxaprozin is a non-steroidal anti-inflammatory drug prescribed for rheumatoid arthritis (RA) and osteoarthritis (OA). Oxaprozin binds to albumin. It inhibits arachidonic acid pathway. Oxaprozin has anti-inflammatory property and is an effective inhibitor of cyclooxygenase enzymes, COX-1 and COX-2. Application Anti-inflammatory |
ALogP | 4.2 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid |
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INCHI | InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21) |
InChi Key | OFPXSFXSNFPTHF-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3 |
Isomeric SMILES | C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3 |
WGK Germany | 3 |
RTECS | HP3090000 |
PubChem CID | 4614 |
Molecular Weight | 293.32 |
Reaxy-Rn | 1083168 |
DrugBank Ligand | DB00991 |
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PubChem CID | 4614 |
CAS Registry No. | 21256-18-8 |
ChEMBL Ligand | CHEMBL1071 |
Wikipedia | Oxaprozin |
DrugCentral Ligand | 2013 |
RCSB PDB Ligand | BJ6 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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E2411404 | Certificate of Analysis | Mar 22, 2024 | O129611 |
E2411405 | Certificate of Analysis | Mar 22, 2024 | O129611 |
E2411406 | Certificate of Analysis | Mar 22, 2024 | O129611 |
K2112320 | Certificate of Analysis | Aug 17, 2023 | O129611 |
K2112358 | Certificate of Analysis | Aug 17, 2023 | O129611 |
K2112388 | Certificate of Analysis | Aug 17, 2023 | O129611 |
K2112635 | Certificate of Analysis | Aug 17, 2023 | O129611 |
G1721077 | Certificate of Analysis | Feb 06, 2023 | O129611 |
Solubility | Soluble in water (8.8 mg/L) at 25 °C, DMSO, and methanol. |
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Melt Point(°C) | 163 °C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H412:Harmful to aquatic life with long lasting effects H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
RTECS | HP3090000 |
Reaxy-Rn | 1083168 |
Merck Index | 6924 |