Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P431534-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
P431534-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $19.90 | |
P431534-100g | 100g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $49.90 | |
P431534-250g | 250g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $99.90 |
Synonyms | 2,3,5,6-Tetrachloro-p-benzoquinone | DivK1c_006946 | EN300-18125 | Spectrum5_001386 | Spergon | 2,5,6-Tetrachloroquinone | 4-Chloranil | Tox21_303021 | CS-0013526 | D72499 | DTXCID20266 | Spergon I | Tetrachloro-p-quinone | p-Benzoquinone,3,5,6-tetrachlor |
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Specifications & Purity | for synthesis |
Storage Temp | Room temperature |
Shipped In | Normal |
Grade | for synthesis |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |
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INCHI | InChI=1S/C6Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11 |
InChi Key | UGNWTBMOAKPKBL-UHFFFAOYSA-N |
Canonical SMILES | C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl |
Isomeric SMILES | C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl |
WGK Germany | 2 |
RTECS | DK6825000 |
PubChem CID | 8371 |
Molecular Weight | 245.88 |
Beilstein | 393006 |
Reaxy-Rn | 393006 |
Enter Lot Number to search for COA:
Solubility | practically insoluble 0.25g/L |
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Melt Point(°C) | 290°C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 2 |
RTECS | DK6825000 |
Reaxy-Rn | 393006 |
Merck Index | 2078 |
1. Tiemei Li, Lichong Duan, Mengmeng Du, Longrui Shi, Wenjuan Zhu, Chen Wang, Jing Fan. (2024) Hydrophobic deep eutectic solvent-based vortex assisted liquid–liquid microextraction for the determination of famciclovir in water samples coupled with high performance liquid chromatography. MICROCHEMICAL JOURNAL, 197 (109697). [PMID:18694559] [10.1016/j.microc.2023.109697] |
2. Yiran Wang, Xinyu Yang, Xueting Lu, Xiaonian Cao, Ling Ao, Lele Ma, Caihong Shen, Yongqian Fu, Yaqiong Yang. (2024) BODIPY-labeled aptasensor based on multi-walled carbon nanotubes as the quencher for “off–on” detection of catechin. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 306 (24): (123597). [PMID:37925958] [10.1016/j.saa.2023.123597] |
3. Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan. (2024) Highly bright stable organic radicals encapsulated by amphiphilic polypeptide for efficient near-infrared phototheranostics. TALANTA, 266 (124948). [PMID:37459788] [10.1016/j.talanta.2023.124948] |
4. Cuiping Li, Mengfan Pang, Yaping Li, Lirong Han, Yajiao Fan, Xuelian Xin, Xian Zhang, Ning Zhang, Yan Qin. (2023) Protective effect of vitamin C against tetrachlorobenzoquinone-induced 5-hydroxymethylation-dependent apoptosis in HepG2 cells mainly via the mitochondrial apoptosis pathway. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 260 (115097). [PMID:37271103] [10.1016/j.ecoenv.2023.115097] |
5. Bingwei Yang, Zhishuai Ye, Xiangyu Zhu, Rongchong Huang, Erqun Song, Yang Song. (2023) The redox activity of polychlorinated biphenyl quinone metabolite orchestrates its pro-atherosclerosis effect via CAV1 phosphorylation. JOURNAL OF HAZARDOUS MATERIALS, 457 (131697). [PMID:37257380] [10.1016/j.jhazmat.2023.131697] |
6. Lu Lin, Zirui Lin, Jiaqi Zhu, Kuo Wang, Wanlong Wu, Tong Qiu, Xiaoqi Sun. (2023) A semi-conductive organic cathode material enabled by extended conjugation for rechargeable aqueous zinc batteries. Energy & Environmental Science, 16 (1): (89-96). [PMID:] [10.1039/D2EE02961H] |
7. Yunhao Yu, Rui Tian, Yu Zhao, Xudong Qin, Liefeng Hu, Jun-Jie Zou, Ying-Wei Yang, Jian Tian. (2022) Self-Assembled Corrole/Chitosan Photothermal Nanoparticles for Accelerating Infected Diabetic Wound Healing. Advanced Healthcare Materials, 12 (16): (2201651). [PMID:36168853] [10.1002/adhm.202201651] |
8. Ruijuan Duan, Meiling Qi. (2022) Separation performance of pentiptycene-functionalized triblock copolymers towards the isomers of xylenes, phenols and anilines and the complex components in essential oil. JOURNAL OF CHROMATOGRAPHY A, 1669 (462927). [PMID:35278809] [10.1016/j.chroma.2022.462927] |
9. Ya-Ting Gao, Bin-Bin Chen, Lei Jiang, Jian Lv, Shuai Chang, Yue Wang, Ruo-Can Qian, Da-Wei Li, Mahmoud Elsayed Hafez. (2021) Dual-Emitting Carbonized Polymer Dots Synthesized at Room Temperature for Ratiometric Fluorescence Sensing of Vitamin B12. ACS Applied Materials & Interfaces, 13 (42): (50228–50235). [PMID:34651499] [10.1021/acsami.1c12993] |
10. Yan Chen, Zhao Mo, Xingtong Zhu, Qingxiang Xu, Zhaoli Xue, Henan Li, Hui Xu, Long Zhao. (2021) Facilitated interfacial charge separation using triphenylamine-zinc porphyrin dyad-sensitized TiO2 nanoparticles for photocatalysis. JOURNAL OF ALLOYS AND COMPOUNDS, 889 (161795). [PMID:] [10.1016/j.jallcom.2021.161795] |
11. Lin Zirui, Shi Hua-Yu, Lin Lu, Yang Xianpeng, Wu Wanlong, Sun Xiaoqi. (2021) A high capacity small molecule quinone cathode for rechargeable aqueous zinc-organic batteries. Nature Communications, 12 (1): (1-9). [PMID:34285215] [10.1038/s41467-021-24701-9] |
12. Qingxiang Xu, Long Zhao, Yuhan Ma, Rui Yuan, Maosong Liu, Zhaoli Xue, Henan Li, Jianming Zhang, Xinping Qiu. (2021) Substituents and the induced partial charge effects on cobalt porphyrins catalytic oxygen reduction reactions in acidic medium. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 597 (269). [PMID:33872883] [10.1016/j.jcis.2021.04.009] |
13. Xuying Lv, Zixuan Liu, Lei Xu, Erqun Song, Yang Song. (2021) Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop. ENVIRONMENTAL POLLUTION, 268 (115921). [PMID:33187846] [10.1016/j.envpol.2020.115921] |
14. Long Zhao, Qingxiang Xu, Zhiwen Shao, Yan Chen, Zhaoli Xue, Henan Li, Jianming Zhang. (2020) Enhanced Oxygen Reduction Reaction Performance Using Intermolecular Forces Coupled with More Exposed Molecular Orbitals of Triphenylamine in Co-porphyrin Electrocatalysts. ACS Applied Materials & Interfaces, 12 (41): (45976–45986). [PMID:32975398] [10.1021/acsami.0c11742] |
15. Lu Yan, Chang Zhaosen, Zhang Shizhen, Wang Shunli, Chen Qi, Feng Lijuan, Sui Zhuyin. (2020) Porous organic polymers containing zinc porphyrin and phosphonium bromide as bifunctional catalysts for conversion of carbon dioxide. JOURNAL OF MATERIALS SCIENCE, 55 (26): (11856-11869). [PMID:] [10.1007/s10853-020-04851-9] |
16. Bowen Xiang, Yudong Xue, Zhiyong Liu, Jia Tian, Holger Frey, Yun Gao, Weian Zhang. (2020) Water-soluble hyperbranched polyglycerol photosensitizer for enhanced photodynamic therapy. Polymer Chemistry, 11 (23): (3913-3921). [PMID:] [10.1039/D0PY00431F] |
17. Kaiyao Shi, Yang Liu, Jingru Ma, Yuqing Zhao, Liang Liu, Jingying Wang. (2020) A series of aromatric-amine-cored fluorescent emitters for amplified spontaneous laser emission and emission turn-on sensing. JOURNAL OF LUMINESCENCE, 223 (117165). [PMID:] [10.1016/j.jlumin.2020.117165] |
18. Man Du, Yue Zhang, Yifeng Yu, Hua Zhao, Yue Guo, Yunxu Yang. (2019) A highly sensitive and selective fluorescent probe based on a Pd-catalyzed reaction for detection of Pd2+. Analytical Methods, 11 (47): (6053-6061). [PMID:] [10.1039/C9AY02212K] |
19. Xiaoqi Chen, Wei Wang, Cheng Wang, Zijia Liu, Qi Sun, Dongmei Wang. (2019) Quality evaluation and chemometric discrimination of Zanthoxylum bungeanum Maxim leaves based on flavonoids profiles, bioactivity and HPLC-fingerprint in a common garden experiment. INDUSTRIAL CROPS AND PRODUCTS, 134 (225). [PMID:] [10.1016/j.indcrop.2019.04.017] |
20. Chao Xu, Ying Qian. (2019) A selenamorpholine-based redox-responsive fluorescent probe for targeting lysosome and visualizing exogenous/endogenous hydrogen peroxide in living cells and zebrafish. Journal of Materials Chemistry B, 7 (16): (2714-2721). [PMID:32255004] [10.1039/C8TB03010C] |
21. Xiaomin Xia, Bin Lu, Wenjing Dong, Bingwei Yang, Yawen Wang, Qi Qin, Zixuan Liu, Erqun Song, Yang Song. (2018) Atypical Gasdermin D and Mixed Lineage Kinase Domain-like Protein Leakage Aggravates Tetrachlorobenzoquinone-Induced Nod-like Receptor Protein 3 Inflammasome Activation. CHEMICAL RESEARCH IN TOXICOLOGY, 31 (12): (1418–1425). [PMID:30378427] [10.1021/acs.chemrestox.8b00306] |
22. Zixuan Liu, Wenjing Dong, Bingwei Yang, Lu Peng, Xiaomin Xia, Lanxiang Pu, Na Zhang, Erqun Song, Yang Song. (2018) Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis. CHEMICAL RESEARCH IN TOXICOLOGY, 31 (11): (1230–1239). [PMID:30358983] [10.1021/acs.chemrestox.8b00209] |
23. Chao Xu, Ying Qian, Zheng-qing Qi, Chang-gui Lu, Yi-ping Cui. (2018) A conjugated BODIPY–triphenylamine multi-aldoxime: Sonogashira coupling, ratiometric chemodosimeter and rapid detection of hypochlorite with two-photon excited fluorescence. NEW JOURNAL OF CHEMISTRY, 42 (9): (6910-6917). [PMID:] [10.1039/C8NJ00368H] |
24. Zixuan Liu, Yawen Wang, Yuxin Wang, Wenjing Dong, Xiaomin Xia, Erqun Song, Yang Song. (2017) Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis. CHEMICAL RESEARCH IN TOXICOLOGY, 30 (10): (1804–1814). [PMID:28823167] [10.1021/acs.chemrestox.7b00118] |
25. Meiding Yang, Huipeng Zhou, Yongxin Li, Qingfeng Zhang, Juanmin Li, Cuiyun Zhang, Chuibei Zhou, Cong Yu. (2017) Peroxidase activity of the coronene bisimide supramolecular architecture and its applications in colorimetric sensing of H2O2 and glucose. Journal of Materials Chemistry B, 5 (32): (6572-6578). [PMID:32264419] [10.1039/C7TB00212B] |
26. Wenbei Zhang, Tianlu Cui, Lingyun Yang, Chao Zhang, Ming Cai, Sai Sun, Yefeng Yao, Xiaodong Zhuang, Fan Zhang. (2017) Hollow-structured conjugated porous polymer derived Iron/Nitrogen-codoped hierarchical porous carbons as highly efficient electrocatalysts. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 497 (108). [PMID:28279867] [10.1016/j.jcis.2017.02.061] |
27. Lu Li, Ai-hong Peng, Zheng-zhong Lin, Hui-ping Zhong, Xiao-mei Chen, Zhi-yong Huang. (2017) Biomimetic ELISA detection of malachite green based on molecularly imprinted polymer film. FOOD CHEMISTRY, 229 (403). [PMID:28372192] [10.1016/j.foodchem.2017.02.090] |
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29. Xiufang Song, Qiong Shi, Zixuan Liu, Yawen Wang, Yuxin Wang, Erqun Song, Yang Song. (2016) Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone. CHEMICAL RESEARCH IN TOXICOLOGY, 29 (12): (2184–2193). [PMID:27989139] [10.1021/acs.chemrestox.6b00369] |
30. Xiaoxue Wu, Shan Sun, Yuhui Wang, Jiali Zhu, Kai Jiang, Yumin Leng, Qinghai Shu, Hengwei Lin. (2017) A fluorescent carbon-dots-based mitochondria-targetable nanoprobe for peroxynitrite sensing in living cells. BIOSENSORS & BIOELECTRONICS, 90 (501). [PMID:27825883] [10.1016/j.bios.2016.10.060] |
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1. Tiemei Li, Lichong Duan, Mengmeng Du, Longrui Shi, Wenjuan Zhu, Chen Wang, Jing Fan. (2024) Hydrophobic deep eutectic solvent-based vortex assisted liquid–liquid microextraction for the determination of famciclovir in water samples coupled with high performance liquid chromatography. MICROCHEMICAL JOURNAL, 197 (109697). [PMID:18694559] [10.1016/j.microc.2023.109697] |
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