Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C108514-5g | 5g | In stock | $13.90 | |
C108514-25g | 25g | In stock | $52.90 | |
C108514-100g | 100g | In stock | $152.90 | |
C108514-250g | 250g | In stock | $344.90 | |
C108514-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $465.90 |
Synonyms | Dehydroepiandrosterone-[D6] (CertiMass solution) | Para-Coumaric acid | b-[4-Hydroxyphenyl]acrylate | Cinnamic acid, 4-hydroxy-, trans- | Para-Coumarate | trans-p-Hydroxycinnamic acid | SODIUM2,4-PENTANEDIONATE | 3-(4-Hydroxyphenyl)-2-propenoate | 4-10-00 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | p-Coumaric acid is mainly a plant metabolite which exhibits antioxidant and anti-inflammatory properties It also shows bactericidal activity by damaging bacterial cell membrane and by interacting with bacterial DNA. In western blot, p-coumaric is also use |
Storage Temp | Argon charged |
Shipped In | Normal |
Grade | Moligand™ |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488190845 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488190845 |
IUPAC Name | (E)-3-(4-hydroxyphenyl)prop-2-enoic acid |
INCHI | InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+ |
InChi Key | NGSWKAQJJWESNS-ZZXKWVIFSA-N |
Canonical SMILES | C1=CC(=CC=C1C=CC(=O)O)O |
Isomeric SMILES | C1=CC(=CC=C1/C=C/C(=O)O)O |
WGK Germany | 2 |
RTECS | GD9095000 |
PubChem CID | 637542 |
Molecular Weight | 164.16 |
Beilstein | 2207383 |
PubChem SID | 488190845 |
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Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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L2405542 | Certificate of Analysis | Jun 26, 2024 | C108514 |
L2405541 | Certificate of Analysis | Jun 26, 2024 | C108514 |
L2405540 | Certificate of Analysis | Jun 26, 2024 | C108514 |
C2307644 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307651 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307649 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307646 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307630 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307582 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307580 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307561 | Certificate of Analysis | Jan 02, 2023 | C108514 |
C2307559 | Certificate of Analysis | Jan 02, 2023 | C108514 |
B2223347 | Certificate of Analysis | Jan 10, 2022 | C108514 |
C2212529 | Certificate of Analysis | Jan 10, 2022 | C108514 |
B2223373 | Certificate of Analysis | Jan 10, 2022 | C108514 |
D2407069 | Certificate of Analysis | Jan 10, 2022 | C108514 |
H2401052 | Certificate of Analysis | Jan 10, 2022 | C108514 |
L22151180 | Certificate of Analysis | Jan 10, 2022 | C108514 |
B2223371 | Certificate of Analysis | Jan 10, 2022 | C108514 |
B2223370 | Certificate of Analysis | Jan 10, 2022 | C108514 |
B2223348 | Certificate of Analysis | Jan 10, 2022 | C108514 |
H2121244 | Certificate of Analysis | Jul 02, 2021 | C108514 |
Solubility | Solubility in Methanol very faint turbidity,Slightly soluble in water |
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Sensitivity | air sensitive |
Melt Point(°C) | 210-214°C |
Pictogram(s) | GHS06, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H311:Toxic in contact with skin H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | GD9095000 |
Merck Index | 2560 |
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2. Xiao-Li Yin, Zhi-Xin Peng, Yuan Pan, Yi Lv, Wanjun Long, Hui-Wen Gu, Haiyan Fu, Yuanbin She. (2023) UHPLC-QTOF-MS-based untargeted metabolomic authentication of Chinese red wines according to their grape varieties. FOOD RESEARCH INTERNATIONAL, (113923). [PMID:38309902] [10.1016/j.foodres.2023.113923] |
3. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Mei Deng, Yanxia Chen, Mingwei Zhang. (2023) The effects of different enzymes on the liberation of bound phenolics from rice bran dietary fibre and their antioxidant activities. Food Bioscience, 56 (103449). [PMID:] [10.1016/j.fbio.2023.103449] |
4. Daihong Gao, Denghao Ouyang, Xuebing Zhao. (2024) Controllable oxidative depolymerization of lignin to produce aromatic aldehydes and generate electricity under mild conditions with direct biomass fuel cells as flexible reactors. CHEMICAL ENGINEERING JOURNAL, 479 (147874). [PMID:] [10.1016/j.cej.2023.147874] |
5. Jianli Zhou, Chuqi Tang, Shuliang Zou, Liangbo Lei, Yuangen Wu, Wenhua Yang, Jean Damascene Harindintwali, Jiang Zhang, Wenwen Zeng, Dan Deng, Manman Zhao, Xiaobin Yu, Xiaobo Liu, Shuyi Qiu, Nils Arneborg. (2024) Enhancement of pyranoanthocyanin formation in blueberry wine with non-Saccharomyces yeasts. FOOD CHEMISTRY, 438 (5): (137956). [PMID:37989022] [10.1016/j.foodchem.2023.137956] |
6. Jinxin Li, Hao Zhang, Ling Zhu, Gangcheng Wu, Hui Zhang. (2023) Influence of in vitro gastrointestinal digestion and colonic fermentation on carbonyl scavenging capacity of fiber-bound polyphenols from quinoa. Food & Function, 14 (23): (10581-10590). [PMID:37955444] [10.1039/D3FO03000H] |
7. Yueqin Li, Yunzhen Zhang, Lezhen Dong, Ying Li, Yahui Liu, Yang Liu, Lingyi Liu, Lianliang Liu. (2024) Fermentation of Lactobacillus fermentum NB02 with feruloyl esterase production increases the phenolic compounds content and antioxidant properties of oat bran. FOOD CHEMISTRY, 437 (15): (137834). [PMID:37897817] [10.1016/j.foodchem.2023.137834] |
8. Dong Wu, Huihui Ming, Wei Wu, Wenjie Yu, Gaowei Zhang, Jinzhu Gu, Meng Cui, Xueyong Huang, Fangjian Ning, Liping Luo. (2024) In situ neutral desorption-extractive electrospray ionization mass spectrometry reveals red-blue light promoted the accumulation of amino acids and polyphenols in Anoectochilus roxburghii. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 125 (105761). [PMID:18810425] [10.1016/j.jfca.2023.105761] |
9. Zhaoxin Wang, Ying Zhou, Yuefei Wang, Xiaohui Yan. (2023) Reconstitution and Optimization of the Marmesin Biosynthetic Pathway in Yeast. ACS Synthetic Biology, 12 (10): (2922–2933). [PMID:37767718] [10.1021/acssynbio.3c00267] |
10. Wen Xia, Bingbing Song, Tong Li, Rui Hai Liu. (2023) Phytochemical profiles, antioxidant activities, and synergistic antiproliferative effects of blueberry and apple peel extracts. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, (15): [PMID:37658664] [10.1002/jsfa.12964] |
11. Qiaozhi Zhang, Shiyu Fan, Hujun Xie, Yan Zhang, Linglin Fu. (2023) Polyphenols from pigmented quinoa as potential modulators of maize starch digestion: Role of the starch-polyphenol inclusion and non-inclusion complexes. FOOD HYDROCOLLOIDS, 144 (108975). [PMID:] [10.1016/j.foodhyd.2023.108975] |
12. Ningning Zhao, Junpeng Xing, Zhong Zheng, Fengrui Song, Zhiqiang Liu, Shu Liu. (2023) A novel strategy on the study of whole intestinal metabolic profiles for Polygalae Radix before and after processing. PHYTOCHEMICAL ANALYSIS, 34 (5): (540-547). [PMID:37169718] [10.1002/pca.3234] |
13. Wenwen Guan, Duqin Zhang, Bin Tan. (2023) Effect of Layered Debranning Processing on the Proximate Composition, Polyphenol Content, and Antioxidant Activity of Whole Grain Wheat. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2023 (1083867). [PMID:] [10.1155/2023/1083867] |
14. Shiming Tang, Yukun Chen, Daocheng Liao, Ying Lin, Shuangyan Han, Suiping Zheng. (2023) A process for p-hydroxystyrene production from glycerol based on cell-free biosynthesis system. BIOCHEMICAL ENGINEERING JOURNAL, 195 (108927). [PMID:] [10.1016/j.bej.2023.108927] |
15. Qianwei Ma, Yang Yu, Zhongkai Zhou, Lili Wang, Ruge Cao. (2023) Effects of different treatments on composition, physicochemical and biological properties of soluble dietary fiber in buckwheat bran. Food Bioscience, 53 (102517). [PMID:] [10.1016/j.fbio.2023.102517] |
16. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] [10.1016/j.fbio.2023.102508] |
17. Peichao Zhang, Jing Gao, Haiyang Zhang, Yongzhen Wang, Zhen Liu, Sang Yup Lee, Xiangzhao Mao. (2023) Metabolic engineering of Escherichia coli for the production of an antifouling agent zosteric acid. METABOLIC ENGINEERING, 76 (247). [PMID:36822462] [10.1016/j.ymben.2023.02.007] |
18. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] [10.3390/nu15051078] |
19. Yajie Zuo, Siying Zhu, Yi Liu, Jingjing Zhao, Shiyi Zhang, Chongmin Zhong. (2023) Quantitative Methylation of Lignin Monomers Using Tetrabutylammonium Hydroxide and MeI and Applications in Organic Synthesis. ACS Omega, 8 (7): (7057–7062). [PMID:36844551] [10.1021/acsomega.2c07920] |
20. Li Min, Wang Yayao, Xiao Jianxing, Yan Xingfu, Liu Bingru. (2023) Allelopathic inhibition effects and mechanism of phenolic acids to Microcystis aeruginosa. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (15): (45388-45397). [PMID:36705822] [10.1007/s11356-022-24992-5] |
21. Jiao Wu, Bingjun Han, Xiaoyu Chen, Jinglin Gao, Shan Zhao, Liping Sun, Shijie Wang. (2023) Quantification of bioactive components and evaluation of microbial community and antibacterial activity from Heterotrigona itama and Tetrigona binghami honeys. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2247-2257). [PMID:] [10.1111/ijfs.16325] |
22. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li. (2023) Stability and antioxidant activity of phenolic compounds during in vitro digestion. JOURNAL OF FOOD SCIENCE, 88 (2): (696-716). [PMID:36617678] [10.1111/1750-3841.16440] |
23. Yingjie Lu, Yuqi Cao, Danqing Chen, Yaobin Zhou, Li Zhang, Yue Su, Yinlong Guo. (2023) An online derivatization strategy targeting carbon–carbon double bonds by laser-ablation carbon fiber ionization mass spectrometry imaging: Unraveling the spatial characteristic in mountain-cultivated ginseng and garden-cultivated ginseng with different ages. FOOD CHEMISTRY, 410 (135365). [PMID:36608558] [10.1016/j.foodchem.2022.135365] |
24. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu. (2022) Evaluation of the antioxidant characteristics of craft beer with green tea. JOURNAL OF FOOD SCIENCE, 88 (2): (625-637). [PMID:36576119] [10.1111/1750-3841.16441] |
25. Sheng-Wei Wang, Tian-Yi Wang. (2023) Study on Antibacterial Activity and Structure of Chemically Modified Lysozyme. MOLECULES, 28 (1): (95). [PMID:36615291] [10.3390/molecules28010095] |
26. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang. (2023) Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China). Foods, 12 (1): (7). [PMID:36613224] [10.3390/foods12010007] |
27. Fan-Zhi Bu, Yue-Ming Yu, Yu Yu, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li. (2023) Self-assembly of antifungal agent 5-fluorocytosine and nutrient trans-p-coumaric acid furnishes a cocrystal with the potential to reduce toxicity and side effects for the drug: a case study combining theory with experiment. NEW JOURNAL OF CHEMISTRY, 47 (3): (1328-1341). [PMID:] [10.1039/D2NJ03622C] |
28. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
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