p-Toluenesulfonamide - Analytical Reagent, 98%, high purity , CAS No.70-55-3

  • AR
  • ≥98%
Item Number
T102876
Grouped product items
SKUSizeAvailabilityPrice Qty
T102876-25g
25g
In stock
$9.90
T102876-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$14.90
T102876-250g
250g
In stock
$28.90
T102876-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$44.90

Basic Description

SynonymsEINECS 200-741-1 | CAS-70-55-3 | AE-562/40173366 | NSC-9908 | Paratoulene sulfonamide | p-toluenesulfonic amide | 4-Toluenesulfonic acid, amide | p-methyl-benzene sulfonamide | para-toluen sulphonamide | Benzenesulfonamide, 4-methyl- | p-Toluenesulfonamid
Specifications & PurityAR, ≥98%
Shipped InNormal
GradeAR

Associated Targets(Human)

CA5A Tclin Carbonic anhydrase 5A, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GMNN Tbio Geminin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
QPCT Tchem Glutaminyl-peptide cyclotransferase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TNF Tclin Tumor necrosis factor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP1 Tchem Interstitial collagenase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP9 Tchem Matrix metalloproteinase-9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP2 Tchem 72 kDa type IV collagenase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA5B Tclin Carbonic anhydrase 5B, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA6 Tclin Carbonic anhydrase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA13 Tclin Carbonic anhydrase 13 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA1 Tclin Carbonic anhydrase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA3 Tclin Carbonic anhydrase 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (38 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA12 Tclin Carbonic anhydrase 12 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA9 Tclin Carbonic anhydrase 9 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AHR Tclin Aryl hydrocarbon receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Stromelysin-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP8 Tchem Neutrophil collagenase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNF Tclin TNF-alpha (1897 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA3 Tclin Carbonic anhydrase III (753 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A498 (42825 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHN (49357 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
COLO 205 (50209 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KM12 (47707 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-5 (45555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-8 (47708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-8226 (44974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 393 (41971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-295 (48000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-2 (46422 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-5 (47095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-19 (46794 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK-10 (45540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-251 (51189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-257 (46019 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-62 (47335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UO-31 (46270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
786-0 (47912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI/ADR-RES (33767 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EKVX (44102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H322M (45589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonic anhydrase (69 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
cynT Carbonic anhydrase 1 (82 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca15 Carbonic anhydrase 15 (173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mtcA1 Uncharacterized protein Rv1284/MT1322 (182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Malassezia furfur (70 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA Alpha carbonic anhydrase (93 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAN2 Carbonic anhydrase 2 (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Astrosclerin-3 (80 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Malassezia pachydermatis (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ca1 Delta carbonic anhydrase (40 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
1272966 AGAP002992-PA (40 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonic anhydrase, alpha family (44 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonate dehydratase (40 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180035
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180035
IUPAC Name 4-methylbenzenesulfonamide
INCHI InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)
InChi Key LMYRWZFENFIFIT-UHFFFAOYSA-N
Canonical SMILES CC1=CC=C(C=C1)S(=O)(=O)N
Isomeric SMILES CC1=CC=C(C=C1)S(=O)(=O)N
WGK Germany 1
RTECS XT5075000
PubChem CID 6269
Molecular Weight 171.22
Beilstein 472689

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
K2408655Certificate of AnalysisJul 27, 2024 T102876
K2408656Certificate of AnalysisJul 27, 2024 T102876
E2430483Certificate of AnalysisMar 23, 2024 T102876
E2430484Certificate of AnalysisMar 23, 2024 T102876
E2430563Certificate of AnalysisMar 23, 2024 T102876
G2411424Certificate of AnalysisMar 23, 2024 T102876
H2423074Certificate of AnalysisMar 23, 2024 T102876
I2305264Certificate of AnalysisSep 07, 2023 T102876
I2411134Certificate of AnalysisOct 24, 2022 T102876
J2221448Certificate of AnalysisOct 24, 2022 T102876
A2224259Certificate of AnalysisFeb 10, 2022 T102876
A2224260Certificate of AnalysisFeb 10, 2022 T102876
A2224261Certificate of AnalysisFeb 10, 2022 T102876
A2415207Certificate of AnalysisFeb 10, 2022 T102876
B2307238Certificate of AnalysisFeb 10, 2022 T102876

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Chemical and Physical Properties

SolubilitySoluble in water (3.16 mg/ml at 25 °C), alcohol, DMSO, methanol, and ethanol (at 20°C).
SensitivityMoisture sensitive.
Flash Point(°F)395.6 °F
Flash Point(°C)202 °C
Boil Point(°C)214 °C/9.98 mmHg
Melt Point(°C)134-137°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H330:Fatal if inhaled

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P320:Specific treatment is urgent (see ... on this label).

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

WGK Germany 1
RTECS XT5075000

Related Documents

Citations of This Product

1. Yuehua Deng, Wei Luo, Zhiyong Zheng, Guixuan Wei, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang.  (2023)  Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation.  CHEMICAL ENGINEERING SCIENCE,  272  (118618).  [PMID:] [10.1016/j.ces.2023.118618]
2. Jiayi Lu, Liping Chen, Zhonglin Luo, Biaobing Wang.  (2022)  A vanillin-containing DOPO-based compound for improving the flame retardancy of epoxy resin simultaneously with comparable transparency and mechanical property.  JOURNAL OF APPLIED POLYMER SCIENCE,  140  (9): (e53556).  [PMID:] [10.1002/app.53556]
3. Liping Chen, Qing Jiang, Zhonglin Luo, Biaobing Wang.  (2021)  Facile synthesis of a reactive P/N/S-containing compound toward highly effective flame retardancy of epoxy resin with high transparency and improved mechanical strength.  FIRE SAFETY JOURNAL,  126  (103472).  [PMID:] [10.1016/j.firesaf.2021.103472]
4. Zengduo Cui, Xin Wang, Jiale Ding, Yunhe Zhang, Zhenhua Jiang, Xuefeng Li.  (2020)  Hyperbranched lutecium phthalocyanines grafted ethylenediamine@graphene oxide with enhanced nonlinear optical properties.  JOURNAL OF PORPHYRINS AND PHTHALOCYANINES,  24  (8): (1038-1046).  [PMID:] [10.1142/S1088424620500169]
5. Yüfang Wu, Xiaolu Zhang, Yanchao Di, Yu Kang, Li Bai.  (2017)  Solubility and Mixing Thermodynamics Properties of p-Toluenesulfonamide and o-Toluenesulfonamide in Seven Monosolvents at Different Temperatures.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,  62  (11): (4015–4026).  [PMID:] [10.1021/acs.jced.7b00714]

References

1. Vullo D, Innocenti A, Nishimori I, Pastorek J, Scozzafava A, Pastoreková S, Supuran CT.  (2005)  Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?.  Bioorg Med Chem Lett,  15  (4): (963-9).  [PMID:15686894] [10.1021/op500134e]
2. B M Hausen.  (1995-03-01)  A simple method of determining TS-F-R in nail polish..  Contact dermatitis,  32  ((3)): (188-190).  [PMID:7774209]
3. G Li,K B Sharpless.  (1996-08-01)  Catalytic asymmetric aminohydroxylation provides a short taxol side-chain synthesis..  Acta chemica Scandinavica (Copenhagen, Denmark : 1989),  50  ((8)): (649-651).  [PMID:8756354]
4. S B Levy.  (1998-07-17)  Allergenic ingredients in nail polishes..  Contact dermatitis,  38  ((5)): (303-303).  [PMID:9667464]
5. A M van Haperen,J W van Velde,C G van Ginkel.  (2001-12-04)  Biodegradation of p-toluenesulphonamide by a Pseudomonas sp..  FEMS microbiology letters,  204  ((2)): (299-304).  [PMID:11731139]
6. Padmakar V Khadikar,Vimukta Sharma,Sneha Karmarkar,Claudiu T Supuran.  (2005-02-03)  QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II..  Bioorganic & medicinal chemistry letters,  15  ((4)): (923-930).  [PMID:15686888]
7. Padmakar V Khadikar,Vimukta Sharma,Sneha Karmarkar,Claudiu T Supuran.  (2005-02-03)  Novel use of chemical shift in NMR as molecular descriptor: a first report on modeling carbonic anhydrase inhibitory activity and related parameters..  Bioorganic & medicinal chemistry letters,  15  ((4)): (931-936).  [PMID:15686889]
8. Daniela Vullo,Juha Voipio,Alessio Innocenti,Claudio Rivera,Harri Ranki,Andrea Scozzafava,Kai Kaila,Claudiu T Supuran.  (2005-02-03)  Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides..  Bioorganic & medicinal chemistry letters,  15  ((4)): (971-976).  [PMID:15686895]
9. Isao Nishimori,Daniela Vullo,Alessio Innocenti,Andrea Scozzafava,Antonio Mastrolorenzo,Claudiu T Supuran.  (2005-11-24)  Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors..  Journal of medicinal chemistry,  48  ((24)): (7860-7866).  [PMID:16302824]
10. Isao Nishimori,Daniela Vullo,Tomoko Minakuchi,Kaori Morimoto,Saburo Onishi,Andrea Scozzafava,Claudiu T Supuran.  (2006-02-07)  Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori..  Bioorganic & medicinal chemistry letters,  16  ((8)): (2182-2188).  [PMID:16459077]
11. Isao Nishimori,Tomoko Minakuchi,Kaori Morimoto,Shuichi Sano,Saburo Onishi,Hiroaki Takeuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran.  (2006-03-17)  Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs..  Journal of medicinal chemistry,  49  ((6)): (2117-2126).  [PMID:16539401]
12. Jiang-Quan Zhou,Zhi-Qiang Tang,Jin-Nan Zhang,Jing-Cheng Tang.  (2006-04-22)  Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies..  Acta pharmacologica Sinica,  27  ((5)): (635-640).  [PMID:16626521]
13. J Q Zhou,Z Q Tang,J N Zhang.  (2006-10-31)  An evaluation of para toluene-sulfonamide metabolism and effect with regard to CYP isoforms, P-glycoprotein, and drug interactions..  Die Pharmazie,  61  ((10)): (869-873).  [PMID:17069428]
14. Isao Nishimori,Tomoko Minakuchi,Saburo Onishi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran.  (2007-01-19)  Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors..  Journal of medicinal chemistry,  50  ((2)): (381-388).  [PMID:17228881]
15. Sarah L Rolland,Thomas E Carrick,Angus W Walls,John F McCabe.  (2007-03-14)  Dentin decontamination using chloramine T prior to experiments involving bacteria..  Dental materials : official publication of the Academy of Dental Materials,  23  ((12)): (1468-1472).  [PMID:17349688]
16. Christian Lorber,Robert Choukroun,Laure Vendier.  (2007-03-17)  Reaction of p-toluenesulfonylamide and M(NMe2)4 (M = Ti, V): generation of electron-deficient imido complexes of early transition metals..  Inorganic chemistry,  46  ((8)): (3192-3202).  [PMID:17362000]
17. Isao Nishimori,Tomoko Minakuchi,Takuhiro Kohsaki,Saburo Onishi,Hiroaki Takeuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran.  (2007-05-08)  Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors..  Bioorganic & medicinal chemistry letters,  17  ((13)): (3585-3594).  [PMID:17482815]
18. Doreen Richter,Gudrun Massmann,Uwe Dünnbier.  (2008-01-09)  Behaviour and biodegradation of sulfonamides (p-TSA, o-TSA, BSA) during drinking water treatment..  Chemosphere,  71  ((8)): (1574-1581).  [PMID:18179813]
19. Min-ying Li,Hui Meng,Wei-liang Zhu,Shao-zhang Zhou,Hong-yi Li,Ji-ren Zhang.  (2008-02-06)  [Dose-effect relationship of para-toluenesulfonamide for treatment of hepatocellular carcinoma in rats]..  Nan fang yi ke da xue xue bao = Journal of Southern Medical University,  28  ((2)): (249-251).  [PMID:18250054]
20. Vjacheslav M Petrov,Georgiy V Girichev,Heinz Oberhammer,Valentina N Petrova,Nina I Giricheva,Anna V Bardina,Sergey N Ivanov.  (2008-02-28)  Molecular structure and conformations of para-methylbenzene sulfonamide and ortho-methylbenzene sulfonamide: gas electron diffraction and quantum chemical calculations study..  The journal of physical chemistry. A,  112  ((13)): (2969-2976).  [PMID:18302350]
21. Charles H Reynolds,Brett A Tounge,Scott D Bembenek.  (2008-04-03)  Ligand binding efficiency: trends, physical basis, and implications..  Journal of medicinal chemistry,  51  ((8)): (2432-2438).  [PMID:18380424]
22. Semra Isik,Feray Kockar,Meltem Aydin,Oktay Arslan,Ozen Ozensoy Guler,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran.  (2009-01-07)  Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates..  Bioorganic & medicinal chemistry,  17  ((3)): (1158-1163).  [PMID:19124253]
23. Mika Hilvo,Anna Maria Salzano,Alessio Innocenti,Markku S Kulomaa,Andrea Scozzafava,Andrea Scaloni,Seppo Parkkila,Claudiu T Supuran.  (2009-02-06)  Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV..  Journal of medicinal chemistry,  52  ((3)): (646-654).  [PMID:19193158]
24. Tomoko Minakuchi,Isao Nishimori,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran.  (2009-03-26)  Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate..  Journal of medicinal chemistry,  52  ((8)): (2226-2232).  [PMID:19317447]
25. Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Alessio Innocenti,Claudiu T Supuran.  (2009-04-03)  Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis..  Journal of medicinal chemistry,  52  ((9)): (3116-3120).  [PMID:19338333]
26. Alessio Innocenti,Rebecca A Hall,Christine Schlicker,Andrea Scozzafava,Clemens Steegborn,Fritz A Mühlschlegel,Claudiu T Supuran.  (2009-05-20)  Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides..  Bioorganic & medicinal chemistry,  17  ((13)): (4503-4509).  [PMID:19450983]
27. Hui Meng,Min-ying Li,Wei-liang Zhu,Ji-ren Zhang.  (2009-05-23)  [Therapeutic effect of para-toluenesulfonamide on transplanted hepatocarcinoma in nude mice]..  Nan fang yi ke da xue xue bao = Journal of Southern Medical University,  29  ((5)): (1024-1025).  [PMID:19460736]
28. Anthony Bertucci,Alessio Innocenti,Didier Zoccola,Andrea Scozzafava,Sylvie Tambutté,Claudiu T Supuran.  (2009-06-13)  Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides..  Bioorganic & medicinal chemistry,  17  ((14)): (5054-5058).  [PMID:19520577]
29. Jianxing He,Weiqiang Ying,Haihong Yang,Xin Xu,Wenlong Shao,Yubao Guan,Mei Jiang,Yizhuang Wu,Baoliang Zhong,Daoyuan Wang,Steven Tucker,Nanshan Zhong.  (2009-08-12)  Gemcitabine plus cisplatin chemotherapy with concurrent para-toluenesulfonamide local injection therapy for peripherally advanced nonsmall cell lung cancer larger than 3 cm in the greatest dimension..  Anti-cancer drugs,  20  ((9)): (838-844).  [PMID:19668080]
30. Fabrizio Carta,Alfonso Maresca,Adrian Suarez Covarrubias,Sherry L Mowbray,T Alwyn Jones,Claudiu T Supuran.  (2009-10-23)  Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c..  Bioorganic & medicinal chemistry letters,  19  ((23)): (6649-6654).  [PMID:19846301]
31. Pascale Joseph,François Turtaut,Safia Ouahrani-Bettache,Jean-Louis Montero,Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Stephan Köhler,Jean-Yves Winum,Claudiu T Supuran.  (2010-02-18)  Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis..  Journal of medicinal chemistry,  53  ((5)): (2277-2285).  [PMID:20158185]
32. Yohei Munei,Kazunori Shimamoto,Masataka Harada,Tatsusada Yoshida,Hiroshi Chuman.  (2010-12-07)  Correlation analyses on binding affinity of substituted benzenesulfonamides with carbonic anhydrase using ab initio MO calculations on their complex structures (II)..  Bioorganic & medicinal chemistry letters,  21  ((1)): (141-144).  [PMID:21130650]
33. Jennifer A Jacobsen,Jessica L Fullagar,Melissa T Miller,Seth M Cohen.  (2010-12-30)  Identifying chelators for metalloprotein inhibitors using a fragment-based approach..  Journal of medicinal chemistry,  54  ((2)): (591-602).  [PMID:21189019]
34. Anthony Bertucci,Alessio Innocenti,Andrea Scozzafava,Sylvie Tambutté,Didier Zoccola,Claudiu T Supuran.  (2011-01-07)  Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata..  Bioorganic & medicinal chemistry letters,  21  ((2)): (710-714).  [PMID:21208801]
35. Pascale Joseph,Safia Ouahrani-Bettache,Jean-Louis Montero,Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Jean-Yves Winum,Stephan Köhler,Claudiu T Supuran.  (2011-01-22)  A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth..  Bioorganic & medicinal chemistry,  19  ((3)): (1172-1178).  [PMID:21251841]
36. Isao Nishimori,Tomoko Minakuchi,Daniela Vullo,Andrea Scozzafava,Claudiu T Supuran.  (2011-07-16)  Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates..  Bioorganic & medicinal chemistry,  19  ((16)): (5023-5030).  [PMID:21757360]
37. Anna Ohradanova,Daniela Vullo,Silvia Pastorekova,Jaromir Pastorek,Daniel J Jackson,Gert Wörheide,Claudiu T Supuran.  (2012-01-31)  Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana..  Bioorganic & medicinal chemistry,  20  ((4)): (1403-1410).  [PMID:22285172]
38. İsmail Fidan,Ramin Ekhteiari Salmas,Mehmet Arslan,Murat Şentürk,Serdar Durdagi,Deniz Ekinci,Esra Şentürk,Sedat Coşgun,Claudiu T Supuran.  (2015-11-05)  Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives..  Bioorganic & medicinal chemistry,  23  ((23)): (7353-7358).  [PMID:26534780]
39. B M Hausen,M Milbrodt,W A Koenig.  (1995-09-01)  The allergens of nail polish. (I). Allergenic constituents of common nail polish and toluenesulfonamide-formaldehyde resin (TS-F-R)..  Contact dermatitis,  33  ((3)): (157-164).  [PMID:8565455]
40. J R Meinertz,L J Schmidt,G R Stehly,W H Gingerich.  (1999-10-08)  Liquid chromatographic determination of para-toluenesulfonamide in edible fillet tissues from three species of fish..  Journal of AOAC International,  82  ((5)): (1064-1070).  [PMID:10513008]
41. J R Meinertz,G R Stehly,W H Gingerich,S L Greseth.  (2001-10-17)  Performance of a proposed determinative method for p-TSA in rainbow trout fillet tissue and bridging the proposed method with a method for total chloramine-T residues in rainbow trout fillet tissue..  Journal of AOAC International,  84  ((5)): (1332-1336).  [PMID:11601449]
42. Olutosin R Idowu,Philip J Kijak,Jeffery R Meinertz,Larry J Schmidt.  (2004-10-21)  Development and validation of a gas chromatography/mass spectrometry procedure for confirmation of para-toluenesulfonamide in edible fish fillet tissue..  Journal of AOAC International,  87  ((5)): (1098-1108).  [PMID:15493666]
43. G J Pinniger,J D Bruton,H Westerblad,K W Ranatunga.  (2005-07-09)  Effects of a myosin-II inhibitor (N-benzyl-p-toluene sulphonamide, BTS) on contractile characteristics of intact fast-twitch mammalian muscle fibres..  Journal of muscle research and cell motility,  26  ((2-3)): (135-141).  [PMID:16003463]
44. Hidehiko Fujisawa,Eiki Takahashi,Teruaki Mukaiyama.  (2006-04-22)  Lewis base catalyzed Mannich-type reactions between trimethylsilyl enol ethers and aldimines..  Chemistry (Weinheim an der Bergstrasse, Germany),  12  ((19)): (5082-5093).  [PMID:16628757]
45. Isao Nishimori,Tomoko Minakuchi,Saburo Onishi,Daniela Vullo,Alessandro Cecchi,Andrea Scozzafava,Claudiu T Supuran.  (2007-09-11)  Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides..  Bioorganic & medicinal chemistry,  15  ((23)): (7229-7236).  [PMID:17826101]
46. G Luo,D Liu,C Liu.  (2008-06-24)  An efficient solvent-free synthesis of benzoxanthenes catalyzed by BSA or O-TSA..  Preparative biochemistry & biotechnology,  38  ((3)): (265-270).  [PMID:18569873]
47. Ruth E Montes,Grady Hanrahan,Frank A Gomez.  (2008-08-15)  Use of chemometric methodology in optimizing conditions for competitive binding partial filling affinity capillary electrophoresis..  Electrophoresis,  29  ((16)): (3325-3332).  [PMID:18702057]
48. Zhan-Guo Chen,Jun-Fa Wei,Run-Tao Li,Xian-Ying Shi,Peng-Fei Zhao.  (2008-12-26)  Copper powder-catalyzed regio- and stereoselective aminobromination of alpha,beta-unsaturated ketones with TsNH2 and NBS as nitrogen and halogen sources..  The Journal of organic chemistry,  74  ((3)): (1371-1373).  [PMID:19108612]
49. Raffaella Meffe,Claus Kohfahl,Ekkehard Holzbecher,Gudrun Massmann,Doreen Richter,Uwe Dünnbier,Asaf Pekdeger.  (2009-09-22)  Modelling the removal of p-TSA (para-toluenesulfonamide) during rapid sand filtration used for drinking water treatment..  Water research,  44  ((1)): (205-213).  [PMID:19766287]
50. Kui Lu,Ohyun Kwon,Kay M Brummond,Matthew M Davis.  (2010-02-18)  PHOSPHINE-CATALYZED [4+2] ANNULATION: SYNTHESIS OF ETHYL 6-PHENYL-1-TOSYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE..  Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals,  2009  ((86)): (212-224).  [PMID:20161208]
51. Dingben Chen,Zhi-Jing Wang,Weiliang Bao.  (2010-07-30)  Copper-catalyzed cascade syntheses of 2H-benzo[b][1,4]thiazin-3(4H)-ones and quinoxalin-2(1H)-ones through capturing S and N atom respectively from AcSH and TsNH(2)..  The Journal of organic chemistry,  75  ((16)): (5768-5771).  [PMID:20666413]
52. Yang Yang,Yan Zhang,Jianbo Wang.  (2011-09-16)  Lewis acid catalyzed direct cyanation of indoles and pyrroles with N-cyano-N-phenyl-p-toluenesulfonamide (NCTS)..  Organic letters,  13  ((20)): (5608-5611).  [PMID:21916460]
53. Yuehua Deng, Wei Luo, Zhiyong Zheng, Guixuan Wei, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang.  (2023)  Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation.  CHEMICAL ENGINEERING SCIENCE,  272  (118618).  [PMID:] [10.1016/j.ces.2023.118618]
54. Jiayi Lu, Liping Chen, Zhonglin Luo, Biaobing Wang.  (2022)  A vanillin-containing DOPO-based compound for improving the flame retardancy of epoxy resin simultaneously with comparable transparency and mechanical property.  JOURNAL OF APPLIED POLYMER SCIENCE,  140  (9): (e53556).  [PMID:] [10.1002/app.53556]
55. Liping Chen, Qing Jiang, Zhonglin Luo, Biaobing Wang.  (2021)  Facile synthesis of a reactive P/N/S-containing compound toward highly effective flame retardancy of epoxy resin with high transparency and improved mechanical strength.  FIRE SAFETY JOURNAL,  126  (103472).  [PMID:] [10.1016/j.firesaf.2021.103472]
56. Zengduo Cui, Xin Wang, Jiale Ding, Yunhe Zhang, Zhenhua Jiang, Xuefeng Li.  (2020)  Hyperbranched lutecium phthalocyanines grafted ethylenediamine@graphene oxide with enhanced nonlinear optical properties.  JOURNAL OF PORPHYRINS AND PHTHALOCYANINES,  24  (8): (1038-1046).  [PMID:] [10.1142/S1088424620500169]
57. Yüfang Wu, Xiaolu Zhang, Yanchao Di, Yu Kang, Li Bai.  (2017)  Solubility and Mixing Thermodynamics Properties of p-Toluenesulfonamide and o-Toluenesulfonamide in Seven Monosolvents at Different Temperatures.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,  62  (11): (4015–4026).  [PMID:] [10.1021/acs.jced.7b00714]

Solution Calculators