L1912143Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 4-Methylbenzoic acid | P-TOLUIC ACID | 99-94-5 | 4-Toluic acid | p-Methylbenzoic acid | Benzoic acid, 4-methyl- | Crithminic acid | p-Toluylic acid | p-Carboxytoluene | para-Toluic acid | 4-Methyl-Benzoic Acid | Toluate | Toluenecarboxylic acid | NSC 2215 | MFCD00002565 | 4-Methyl ben |
|---|---|
| Specifications & Purity | Melting point standard |
| Shipped In | Normal |
| Grade | Melting point standard |
Associated Targets(Human)
TPMT Tchem Thiopurine S-methyltransferase (0 Activities)
SMN1 Tchem Survival motor neuron protein (0 Activities)
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TMEM97 Tchem Sigma intracellular receptor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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TPMT Tchem Thiopurine S-methyltransferase (45 Activities)
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MCF7 (126967 Activities)
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SMN1 Tchem Survival motor neuron protein (34246 Activities)
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Associated Targets(non-human)
Mus musculus (284745 Activities)
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Rattus norvegicus (775804 Activities)
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SIGMAR1 Sigma-1 receptor (3326 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 4-methylbenzoic acid |
|---|---|
| INCHI | InChI=1S/C8H8O2/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H,9,10) |
| InChi Key | LPNBBFKOUUSUDB-UHFFFAOYSA-N |
| Canonical SMILES | CC1=CC=C(C=C1)C(=O)O |
| Isomeric SMILES | CC1=CC=C(C=C1)C(=O)O |
| WGK Germany | 1 |
| RTECS | XU1575000 |
| PubChem CID | 7470 |
| Molecular Weight | 136.15 |
| Beilstein | 507600 |
| Reaxy-Rn | 507600 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Boil Point(°C) | 274-275°C |
|---|---|
| Melt Point(°C) | 180-181°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 1 |
| RTECS | XU1575000 |
| Reaxy-Rn | 507600 |
| Merck Index | 9535 |
Related Documents
Citations of This Product
| 1. Yingying Liu, Xue Wang, Danyang Zhang, Chen Wang, Haijiao Xie, Hongping Chen, Yunfeng Chai. (2023) Does deprotonated benzoic acid lose carbon monoxide in collision-induced dissociation?. JOURNAL OF MASS SPECTROMETRY, 59 (1): (e4990). [PMID:38146124] [10.1002/jms.4990] |
| 2. Lu-Dan Yu, Yuan-Jun Tong, Nan Li, Xinying Gong, Shaohan Wang, Pengfei Ye, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang. (2023) Carboxylated Covalent Organic Frameworks with Size Adjustment for the Identification of Polychlorinated Biphenyls. ACS ES&T Water, [PMID:] [10.1021/acsestwater.3c00460] |
| 3. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang. (2023) Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature. CATALYSIS TODAY, 423 (114277). [PMID:] [10.1016/j.cattod.2023.114277] |
| 4. Zhiyue Zhao, Zhiwei Jiang, Yizhe Huang, Mebrouka Boubeche, Valentina G. Matveeva, Hector F. Garces, Huixia Luo, Kai Yan. (2023) Facile synthesis of CoSi alloy catalysts with rich vacancies for base- and solvent-free aerobic oxidation of aromatic alcohols. CHINESE JOURNAL OF CATALYSIS, 48 (175). [PMID:] [10.1016/S1872-2067(23)64418-3] |
| 5. Jiakai Qiu, Jing Wang, Mingzhu Ren, Xin Yang, Jianbo Zhang, Xiaolong Zhang, Hongbin Cao, Yongbing Xie. (2023) Comprehensive effect of water matrix on catalytic ozonation of chloride contained saline wastewater. WATER RESEARCH, 234 (119827). [PMID:36889089] [10.1016/j.watres.2023.119827] |
| 6. Xingyu Luo, Fengjiao Li, Fei Peng, Lizhen Huang, Xiaoling Lang, Meiqin Shi. (2021) Strategies for Perfect Confinement of POM@MOF and Its Applications in Producing Defect-Rich Electrocatalyst. ACS Applied Materials & Interfaces, 13 (48): (57803–57813). [PMID:34797968] [10.1021/acsami.1c17808] |
| 7. Shenglu Lu, Yaxuan Jing, Bo Feng, Yong Guo, Xiaohui Liu, Yanqin Wang. (2021) H2-free Plastic Conversion: Converting PET back to BTX by Unlocking Hidden Hydrogen. ChemSusChem, 14 (19): (4242-4250). [PMID:33660432] [10.1002/cssc.202100196] |
| 8. Hefei Wang, Dong Wang, Tian Tian, Wei Ren. (2018) Removal of Organic Compounds Containing a Benzene Ring from Water by Adsorptive Micellar Flocculation. JOURNAL OF SURFACTANTS AND DETERGENTS, 22 (1): (161-174). [PMID:] [10.1002/jsde.12209] |
| 9. Zaiming Chen, Wenjie Ji. (2019) Sorption of ionizable organic chemicals to carbonaceous adsorbents: Solution pH change and contributions of different species. SCIENCE OF THE TOTAL ENVIRONMENT, 647 (1069). [PMID:30180315] [10.1016/j.scitotenv.2018.08.033] |
| 10. Chen Yang, Qi Li, Yong Wu. (2017) Thermodynamic models for determination of solid-liquid equilibrium of the 4-methylbenzoic acid in pure and binary organic solvents. JOURNAL OF MOLECULAR LIQUIDS, 238 (432). [PMID:] [10.1016/j.molliq.2017.05.046] |
References
| 1. Yingying Liu, Xue Wang, Danyang Zhang, Chen Wang, Haijiao Xie, Hongping Chen, Yunfeng Chai. (2023) Does deprotonated benzoic acid lose carbon monoxide in collision-induced dissociation?. JOURNAL OF MASS SPECTROMETRY, 59 (1): (e4990). [PMID:38146124] [10.1002/jms.4990] |
| 2. Lu-Dan Yu, Yuan-Jun Tong, Nan Li, Xinying Gong, Shaohan Wang, Pengfei Ye, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang. (2023) Carboxylated Covalent Organic Frameworks with Size Adjustment for the Identification of Polychlorinated Biphenyls. ACS ES&T Water, [PMID:] [10.1021/acsestwater.3c00460] |
| 3. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang. (2023) Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature. CATALYSIS TODAY, 423 (114277). [PMID:] [10.1016/j.cattod.2023.114277] |
| 4. Zhiyue Zhao, Zhiwei Jiang, Yizhe Huang, Mebrouka Boubeche, Valentina G. Matveeva, Hector F. Garces, Huixia Luo, Kai Yan. (2023) Facile synthesis of CoSi alloy catalysts with rich vacancies for base- and solvent-free aerobic oxidation of aromatic alcohols. CHINESE JOURNAL OF CATALYSIS, 48 (175). [PMID:] [10.1016/S1872-2067(23)64418-3] |
| 5. Jiakai Qiu, Jing Wang, Mingzhu Ren, Xin Yang, Jianbo Zhang, Xiaolong Zhang, Hongbin Cao, Yongbing Xie. (2023) Comprehensive effect of water matrix on catalytic ozonation of chloride contained saline wastewater. WATER RESEARCH, 234 (119827). [PMID:36889089] [10.1016/j.watres.2023.119827] |
| 6. Xingyu Luo, Fengjiao Li, Fei Peng, Lizhen Huang, Xiaoling Lang, Meiqin Shi. (2021) Strategies for Perfect Confinement of POM@MOF and Its Applications in Producing Defect-Rich Electrocatalyst. ACS Applied Materials & Interfaces, 13 (48): (57803–57813). [PMID:34797968] [10.1021/acsami.1c17808] |
| 7. Shenglu Lu, Yaxuan Jing, Bo Feng, Yong Guo, Xiaohui Liu, Yanqin Wang. (2021) H2-free Plastic Conversion: Converting PET back to BTX by Unlocking Hidden Hydrogen. ChemSusChem, 14 (19): (4242-4250). [PMID:33660432] [10.1002/cssc.202100196] |
| 8. Hefei Wang, Dong Wang, Tian Tian, Wei Ren. (2018) Removal of Organic Compounds Containing a Benzene Ring from Water by Adsorptive Micellar Flocculation. JOURNAL OF SURFACTANTS AND DETERGENTS, 22 (1): (161-174). [PMID:] [10.1002/jsde.12209] |
| 9. Zaiming Chen, Wenjie Ji. (2019) Sorption of ionizable organic chemicals to carbonaceous adsorbents: Solution pH change and contributions of different species. SCIENCE OF THE TOTAL ENVIRONMENT, 647 (1069). [PMID:30180315] [10.1016/j.scitotenv.2018.08.033] |
| 10. Chen Yang, Qi Li, Yong Wu. (2017) Thermodynamic models for determination of solid-liquid equilibrium of the 4-methylbenzoic acid in pure and binary organic solvents. JOURNAL OF MOLECULAR LIQUIDS, 238 (432). [PMID:] [10.1016/j.molliq.2017.05.046] |