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p38 gamma/MAPK12 Antibody - Primary antibody, specific to MAPK12, Rabbit IgG

1 Citations
    Application:
  • IHC
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab119728
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab119728-10μl
10μl
In stock
$86.90
Ab119728-50μl
50μl
In stock
$249.90
Ab119728-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
Ab119728-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
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pAb; Rabbit anti Human p38 gamma/MAPK12 Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: MAPK12
Accession#:P53778 Gene ID:6300 MAPK12 p38 gamma

Basic Description

Product Namep38 gamma/MAPK12 Antibody - Primary antibody, specific to MAPK12, Rabbit IgG
SynonymsEC 2.7.11 | ERK3 | ERK-6 | ERK6 | MAPK 12 | P38GAMMA | Extracellular signal-regulated kinase 6 | MAP kinase 12 | MAP kinase p38 gamma | MAPK12 | mitogen-activated protein kinase 12 | mitogen-activated protein kinase 3 | Mitogen-activated protein kinase p3
Specifications & PurityExactAb™, Validated, Carrier Free, 0.4 mg/mL
Host speciesRabbit
SpecificityMAPK12
ImmunogenA synthetic peptide derived from human MAPK12 (AA 106-131).
Positive ControlWB: THP-1, K562 and C6 cell lysates. IHC：Human breast cancer tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human p38 gamma/MAPK12 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/2000
IHC: 1/50-1/100
Protein Function
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.4 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

p38 gamma/MAPK12 Antibody (Ab119728) - Western Blot
All lanes: p38 gamma/MAPK12 Antibody (Ab119728) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 41 kDa
Exposure time: 150.0 s

p38 gamma/MAPK12 Antibody (Ab119728) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p38 gamma/MAPK12 Antibody (Ab119728). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets(Human)

MAPK12 Tchem Mitogen-activated protein kinase 12 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/2000

">

1/500-1/2000

IHC1/50 - 1/100

">

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404139Certificate of AnalysisApr 03, 2024 Ab119728
ZJ23F1202128Certificate of AnalysisDec 20, 2023 Ab119728
ZJ23F1202145Certificate of AnalysisDec 20, 2023 Ab119728

Related Documents

 SDS

 Specification Sheet

FAQs and Articles

FAQ
Immunohistochemical staining protocol for frozen samples (IHC-Fr)
Categories: Protocols
Tags:
IHC Monoclonal antibodies Immunohistochemistry Frozen section Recombinant Antibodies
Immunohistochemistry (IHC) staining antigen retrieval protocol
Categories: Protocols
Tags:
IHC Monoclonal antibodies Immunohistochemistry Recombinant Antibodies Antigen Retrieval
Immunopeptide blocking assay
Categories: Protocols
Tags:
Immunopeptideblocking PolyclonalAntibody SpecificBinding

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Zhu P,Qian J,Xu Z,Meng C,Liu J,Shan W,Zhu W,Wang Y,Yang Y,Zhang W,Zhang Y,Ling Y.  (2020)  Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling..  J Nat Prod,  83  (10.0): (3041-3049).  [PMID:33026807] [10.1021/acs.jnatprod.0c00599]

References

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