Propidium iodide - 10mM in DMSO, high purity , CAS No.25535-16-4

94 Citations
  • 10mM in DMSO
Item Number
P422887
Grouped product items
SKUSizeAvailabilityPrice Qty
P422887-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$172.90

Red-fluorescent DNA stain; membrane impermeant to live cells. Pi staining differentiates live and dead cells

Basic Description

Synonymspropidium iodide | 25535-16-4 | Propidium diiodide | 3,8-Diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridin-5-ium iodide | Propidiumiodide | Propidium Iodine | Propidium (Iodide) | CHEBI:51240 | 3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphena
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsRed-fluorescent DNA stain. Membrane impermeant to live cells. Propidium iodide staining differentiates between live and dead cells in cell populations.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Propidium iodide is a fluorescent intercalating agent used for staining.It functions as an apoptosis marker and has linear DNA-binding capacity. Propidium iodide is an effective indicator of tissue injury

Fluorescent stain for nucleic acids. Cell membrane integrity excludes propidium iodide from staining viable and apoptotic cells. Propidium iodide may be used in flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are early in the apoptosis process.

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BACE1 Tchem Beta-secretase 1 (15641 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Cholinesterases; ACHE & BCHE (1222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Calf thymus DNA (4845 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium;diiodide
INCHI InChI=1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1
InChi Key XJMOSONTPMZWPB-UHFFFAOYSA-M
Canonical SMILES CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-]
Isomeric SMILES CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-]
WGK Germany 3
RTECS SF7949600
PubChem CID 104981
Molecular Weight 668.39
Beilstein 3843838

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SensitivityHygroscopic,Light sensitive
Melt Point(°C)220-225°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H341:Suspected of causing genetic defects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS SF7949600

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41. Ruiling Liu, Liping Zhang, Shangyue Xiao, Hangjun Chen, Yanchao Han, Ben Niu, Weijie Wu, Haiyan Gao.  (2023)  Ursolic acid, the main component of blueberry cuticular wax, inhibits Botrytis cinerea growth by damaging cell membrane integrity.  FOOD CHEMISTRY,  415  (135753).  [PMID:36870211]
42. Na An, Yan Gao, Ying Shi, Xingxing Du, Jianing Cheng, Shuanglong Tang, Pengfei Liu, Huike Yang, Chongshen Guo.  (2023)  Nickel phosphide for MRI-guided synergistic photo-immunotherapy.  JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,  151  (150).  [PMID:]
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44. Zhifang Li, Shulong Wang, Jingjin Zhao, Yanni Luo, Hong Liang, Shulin Zhao, Liangliang Zhang.  (2023)  Gold Nanocluster Encapsulated Nanorod for Tumor Microenvironment Simultaneously Activated NIR-II Photoacoustic/Photothermal Imaging and Cancer Therapy.  Advanced Therapeutics,  (4): (2200350).  [PMID:]
45. Delong Hou, Yong Xu, Jun Yan, Qi Zeng, Zhonghui Wang, Yi Chen.  (2023)  Intracellularly Self-Assembled 2D Materials Induce Apoptotic Cell Death by Impeding Cytosolic Transport.  ACS Nano,  17  (3): (3055–3063).  [PMID:36688625]
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47. Yuhang Du, Shuna Mi, Huihui Wang, Fangwei Yang, Hang Yu, Yunfei Xie, Yahui Guo, Yuliang Cheng, Weirong Yao.  (2023)  Inactivation mechanism of Alternaria alternata by dielectric barrier discharge plasma and its quality control on fresh wolfberries.  FOOD CONTROL,  148  (109620).  [PMID:]
48. Yangying Li, Yuda Zhu, Shiyi Li, Yuman Dong, Chengyu Wan, Xiuxian Yu, Guang Xin, Zeliang Wei, Fan Li, Yilan Wang, Kun Zhang, Qingqiu Chen, Cuicui Zhang, E. Wen, Hai Niu, Wen Huang.  (2022)  Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC-1α pathway.  FREE RADICAL RESEARCH,  56  (9-10): (651-665).  [PMID:36592372]
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50. Ziqing Zhong, Xiping Wu, Mindong Bai, Xiaodian Huang, Qilin Zheng, Chunxiang Ai.  (2022)  Treatments of orange-spotted grouper (Epinephelus coioides) against Cryptocaryon irritans with •OH, ClO2 or HCHO: Survival, physiological and histological response.  JOURNAL OF FISH DISEASES,  46  (3): (215-227).  [PMID:36519440]
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53. Jie Li, Xiufeng Zhang, Ning Han, Peng Wan, Feifei Zhao, Tiantian Xu, Xianfeng Peng, Wenguang Xiong, Zhenling Zeng.  (2022)  Mechanism of Action of Isopropoxy Benzene Guanidine against Multidrug-Resistant Pathogens.  Microbiology Spectrum,  11  (1):   [PMID:36475769]
54. Chao-Qing Li, Xiao-Lin Hou, Dong-Xue Jiang, Bin Zhang, Meng-Wen Ma, Xiao-Ting Xie, Yuan-Di Zhao, Tian-Cai Liu, Bo Liu.  (2022)  Binary Pt/Te Nanoheterostructures with High Photothermal Conversion Efficiency and Anti-inflammatory Action for Enhanced Photothermal Therapy of 4T1 Breast Tumors Guided by Photoacoustic Imaging.  ACS Sustainable Chemistry & Engineering,  10  (50): (16598–16610).  [PMID:]
55. Qiyi Yi, Youguang Pu, Fengmei Chao, Po Bian, Lei Lv.  (2022)  ACAP1 Deficiency Predicts Inferior Immunotherapy Response in Solid Tumors.  Cancers,  14  (23): (5951).  [PMID:36497434]
56. Ren Junyu, Da Junlong, Wu Wei, Zheng Ce, Hu Narisu.  (2022)  Niobium carbide–mediated photothermal therapy for infected wound treatment.  Frontiers in Bioengineering and Biotechnology,  10    [PMID:36532585]
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58. Yihan Fu, Fei Ye, Xuwu Zhang, Yuchu He, Xiaoyu Li, Yongfu Tang, Jing Wang, Dawei Gao.  (2022)  Decrease in Tumor Interstitial Pressure for Enhanced Drug Intratumoral Delivery and Synergistic Tumor Therapy.  ACS Nano,  16  (11): (18376–18389).  [PMID:36355037]
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66. Shixiong Yi, Ying Zhou, Jiamei Zhang, Min Wang, Shaohui Zheng, Xiao Yang, Lian Duan, Rui L. Reis, Fangyin Dai, Subhas C. Kundu, Bo Xiao.  (2022)  Flat Silk Cocoon-Based Dressing: Daylight-Driven Rechargeable Antibacterial Membranes Accelerate Infected Wound Healing.  Advanced Healthcare Materials,  11  (21): (2201397).  [PMID:35996858]
67. Chen Wang, Lingjun Zeng, Yeyong Li, Chongli Shi, Yi Peng, Ruolin Pan, Mengyan Huang, Susu Wang, Jin Zhang, Hui Li.  (2022)  Decabromodiphenyl ethane induces locomotion neurotoxicity and potential Alzheimer’s disease risks through intensifying amyloid-beta deposition by inhibiting transthyretin/transthyretin-like proteins.  ENVIRONMENT INTERNATIONAL,  168  (107482).  [PMID:35998411]
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70. Minglu Tang, Zhaocong Zhang, Chengwen Ding, Jingqi Li, Yangtian Shi, Tiedong Sun, Chunxia Chen.  (2022)  Two birds with one stone: innovative ceria-loaded gold@platinum nanospheres for photothermal-catalytic therapy of tumors.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  627  (299).  [PMID:35863189]
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73. Zining Hao, Yuchu He, Jing Wang, Xuwu Zhang, Fei Ye, Ze Guan, Xiaokang Liu, Zhenhe Ma, Yi Yuan, Hongming Lou, Dawei Gao.  (2022)  Photocatalysis/enzymolysis-based biomimetic Schottky junction reduces tumor interstitial solid and fluid phases for deep-penetrating tumor therapy.  CHEMICAL ENGINEERING JOURNAL,  446  (137196).  [PMID:]
74. Dan Hu, Jinyong Wu, Jun Li, Long Jin, Xiangsong Chen, Jianming Yao.  (2022)  Effect of isomaltose oligosaccharide on the freeze-drying process and shelf-life of Pediococcus pentosaceus.  LWT-FOOD SCIENCE AND TECHNOLOGY,  163  (113583).  [PMID:]
75. Rui Zhang, Changlin Liu, Ruoxi Zhao, Yaqian Du, Dan Yang, He Ding, Guixin Yang, Shili Gai, Fei He, Piaoping Yang.  (2022)  Engineering oxygen vacancy of MoOx nanoenzyme by Mn doping for dual-route cascaded catalysis mediated high tumor eradication.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  623  (155).  [PMID:35576647]
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77. Zhen Zhao, Hua Zhang, Hongda Chen, Yuanhong Xu, Lina Ma, Zhenxin Wang.  (2022)  An efficient photothermal–chemotherapy platform based on a polyacrylamide/phytic acid/polydopamine hydrogel.  Journal of Materials Chemistry B,  10  (21): (4012-4019).  [PMID:35506396]
78. Yan Li, Shengnan Zhang, Qiongli Bao, Yutan Chu, Hongyu Sun, Yizong Huang.  (2022)  Jasmonic acid alleviates cadmium toxicity through regulating the antioxidant response and enhancing the chelation of cadmium in rice (Oryza sativa L.).  ENVIRONMENTAL POLLUTION,  304  (119178).  [PMID:35367286]
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80. Xinming Zhang, Ruijuan Lv, Lixia Chen, Ruimeng Sun, Yang Zhang, Rongtian Sheng, Ting Du, Yuhan Li, Yanfei Qi.  (2022)  A Multifunctional Janus Electrospun Nanofiber Dressing with Biofluid Draining, Monitoring, and Antibacterial Properties for Wound Healing.  ACS Applied Materials & Interfaces,  14  (11): (12984–13000).  [PMID:35266385]
81. Yang Zhang, Lixia Chen, Ruimeng Sun, Ruijuan Lv, Ting Du, Yuhan Li, Xinming Zhang, Rongtian Sheng, Yanfei Qi.  (2022)  Multienzymatic Antioxidant Activity of Manganese-Based Nanoparticles for Protection against Oxidative Cell Damage.  ACS Biomaterials Science & Engineering,  (2): (638–648).  [PMID:35076222]
82. Liu Yu, Shang Wenting, Liu Heng, Hui Hui, Wu Jun, Zhang Wei, Gao Pengli, Guo Kunxiong, Guo Yanli, Tian Jie.  (2022)  Biomimetic manganese-eumelanin nanocomposites for combined hyperthermia-immunotherapy against prostate cancer.  JOURNAL OF NANOBIOTECHNOLOGY,  20  (1): (1-15).  [PMID:35073918]
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93. Qiqi Xu, Yusheng Hua, Yuetong Zhang, Mingzhu Lv, Huan Wang, Yang Pi, Jiani Xie, Chengyan Wang, Yuan Yong.  (2021)  A Biofilm Microenvironment-Activated Single-Atom Iron Nanozyme with NIR-Controllable Nanocatalytic Activities for Synergetic Bacteria-Infected Wound Therapy.  Advanced Healthcare Materials,  10  (22): (2101374).  [PMID:34617410]
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Solution Calculators