(Rac)-PT2399 - 99%, high purity , CAS No.1672662-07-5

  • ≥99%
Item Number
P648266
Grouped product items
SKUSizeAvailabilityPrice Qty
P648266-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$350.90
P648266-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$550.90
P648266-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,650.90
P648266-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,650.90

Basic Description

Specifications & Purity99%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC 50 of 0.01 μM

Form:Solid

IC50& Target:IC50: 0.01 μM (HIF-2α)

Associated Targets(Human)

EPAS1 Tclin Endothelial PAS domain-containing protein 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EPAS1 Tclin Endothelial PAS domain-containing protein 1 (498 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-[[7-(difluoromethylsulfonyl)-2,2-difluoro-1-hydroxy-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile
INCHI InChI=1S/C17H10F5NO4S/c18-9-3-8(7-23)4-10(5-9)27-12-1-2-13(28(25,26)16(19)20)14-11(12)6-17(21,22)15(14)24/h1-5,15-16,24H,6H2
InChi Key MXUSGDMIHGLCNC-UHFFFAOYSA-N
Canonical SMILES C1C2=C(C=CC(=C2C(C1(F)F)O)S(=O)(=O)C(F)F)OC3=CC(=CC(=C3)C#N)F
Isomeric SMILES C1C2=C(C=CC(=C2C(C1(F)F)O)S(=O)(=O)C(F)F)OC3=CC(=CC(=C3)C#N)F
PubChem CID 117947087
Molecular Weight 419.32

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilityDMSO : 120 mg/mL (286.18 mM; Need ultrasonic)

Related Documents

Solution Calculators