P7C3 - 98%, high purity , CAS No.301353-96-8

  • ≥98%
Item Number
P275159
Grouped product items
SKUSizeAvailabilityPrice Qty
P275159-10mg
10mg
In stock
$103.90
P275159-50mg
50mg
In stock
$416.90

Pro-neurogenic and neuroprotective compound

Basic Description

SynonymsP7C3 | 301353-96-8 | 1-(3,6-Dibromo-carbazol-9-yl)-3-phenylamino-propan-2-ol | 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol | 1-anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol | MFCD00572918 | 3,6-Dibromo-alpha-[(phenylamino)methyl]-9H-carbazole-9-etha
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPro-neurogenic and neuroprotective compound. Blocks apoptosis of newborn neurons of the dentate gyrus. Also protects mature neurons. Enhances neurogenesis and additionally improves cognitive behaviour. Blood-brain barrier permeable. Active in vivo .
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

 Product Application:

P7C3 is an aminopropyl carbazole agent with proneurogenic and neuroprotective properties in newborn neural precursor cells of the dentate gyrus. Its analogs may be used in neurodegenerative disease research to study the process of neurogenesis in brain regions such as the subgranular zone of the hippocampal dentate gyrus. P7C3 and its analogs may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as potential drug for the treatment of condition such as Alzheimer′s disease, Parkinson′s disease, amyotrophic lateral sclerosis and traumatic brain injury.

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NSC (149 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol
INCHI InChI=1S/C21H18Br2N2O/c22-14-6-8-20-18(10-14)19-11-15(23)7-9-21(19)25(20)13-17(26)12-24-16-4-2-1-3-5-16/h1-11,17,24,26H,12-13H2
InChi Key FZHHRERIIVOATI-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)NCC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)O
Isomeric SMILES C1=CC=C(C=C1)NCC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)O
PubChem CID 2836187
Molecular Weight 474.19

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
G2227116Certificate of AnalysisJun 08, 2022 P275159
G2227117Certificate of AnalysisJun 08, 2022 P275159

Chemical and Physical Properties

SolubilitySoluble in DMSO to 100 mM
SensitivityLight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS05
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

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Solution Calculators