Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P106868-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $118.90 |
Anticancer agent
Synonyms | 33069-62-4 | P88XT4IS4D | Paclitaxel | Taxol | Taxol A | Yewtaxan | Genaxol | Plaxicel | Abraxane | Ebetaxel | Genetaxyl | Capxol | Cyclopax | Genexol | Intaxel | Mitotax | Paxene | Onxol | TaxAlbin | OncoGel | Pacliex | Paxceed | EmPAC | Onxal | Zisu | Taxus stent | Taxus Liberte | ABI-007 | Padexol | EndoTAG 1 |
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Specifications & Purity | Moligand™, analytical standard, ≥99% |
Biochemical and Physiological Mechanisms | Taxol, an antineoplastic and antimicrotubule agent, posses mechanisms of cytotoxic action and has a broad antineoplastic spectrum compared to the vinca alkaloids. Studies have shown that Taxol is an inhibitor of neurite outgrowth and initiation by destroy |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard, Moligand™ |
Action Type | AGONIST, INHIBITOR |
Mechanism of action | Agonist of Pregnane X receptor;Agonist of TLR4;Inhibitor of tubulin beta class I |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Note: Some researchers have found solubility issues in PBS. The recommended procedure (from researcher feedback) for successful solubilisation is as follows: Solubilise 10 mg of ab120143 in 1.25 mL ethanol absolute, mix well, add 1.25mL Cremophor, homogenise. Store at -20°C and after 24 h, defreeze quickly and solubilise in PBS, no crystallisation observed. Please note, Abcam has not yet tested this method. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. |
ALogP | 2.5 |
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IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
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INCHI | InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1 |
InChi Key | RCINICONZNJXQF-MZXODVADSA-N |
Canonical SMILES | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
Isomeric SMILES | CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
WGK Germany | 3 |
RTECS | DA8340700 |
PubChem CID | 36314 |
UN Number | 2811 |
Packing Group | I |
Molecular Weight | 853.91 |
Beilstein | 1420457 |
PubChem CID | 36314 |
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CAS Registry No. | 33069-62-4 |
DrugBank Ligand | DB01229 |
BindingDB Ligand | 50001839 |
ChEBI | CHEBI:45863 |
Wikipedia | Paclitaxel |
ChEMBL Ligand | CHEMBL428647 |
NURSA Ligand | 10.1621/ZJSTGVJ65V |
RCSB PDB Ligand | TA1 |
PEP | paclitaxel |
DrugCentral Ligand | 2044 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2126748 | Certificate of Analysis | Aug 16, 2023 | P106868 |
B2327845 | Certificate of Analysis | Mar 11, 2023 | P106868 |
H2202414 | Certificate of Analysis | Feb 09, 2023 | P106868 |
D2123071 | Certificate of Analysis | Jan 17, 2023 | P106868 |
Specific Rotation[α] | -49 ° (C=1, MeOH) |
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Melt Point(°C) | 213-216°C |
Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects H413:May cause long lasting harmful effects to aquatic life H318:Causes serious eye damage H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H340:May cause genetic defects H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 3 |
RTECS | DA8340700 |
Class | 6.1 |
Merck Index | 6982 |
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9. Hong Shen, Changwei Zhang, Chengzhang Wang, Jianxin Jiang, Fengxia Tang, Chuan Li, Hua Yuan, Xiaoran Yang, Zhenkai Tong, Yi Huang. (2023) Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy. ACS Omega, 8 (34): (31436–31449). [PMID:37663483] |
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23. Zhou LiPing, Li JiaWei, Yu Bing, Zhang Jun, Hu Hao, Cong HaiLin, Shen YouQing. (2023) The drug loading behavior of PAMAM dendrimer: Insights from experimental and simulation study. Science China-Technological Sciences, 66 (4): (1129-1140). [PMID:] |
24. Asmaa S.A. Hammad, Mohamed M. Sayed-Ahmed, Sara Mohamed Naguib Abdel Hafez, Ahmed R.N. Ibrahim, Mohamed M.A. Khalifa, Mahmoud El-Daly. (2023) Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NF-κB and klotho protein expression. CHEMICO-BIOLOGICAL INTERACTIONS, 376 (110446). [PMID:36898573] |
25. Liu Fei, Xu Yanjun, Wang Li, Ma Xifeng, Zhang Zhen, Zhuang Xiaomei. (2023) Combined contributions of cytochrome P450s (CYPs) and non-enzymatic metabolism in the in vitro biotransformation of anaprazole, a novel proton pump inhibitor. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 396 (8): (1759-1771). [PMID:36847804] |
26. Yanzhao Jin, Jiaqing Cao, Hua Cheng, Xiaoyun Hu. (2023) LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma. JOURNAL OF CHEMOTHERAPY, [PMID:36797828] |
27. Wenquan Huang, Zhiqiang Li, Weiqi Liu, Shiyuan Liu, Rujin Zhou, Yanbin Jiang. (2023) Preparation of B16 cancer cell membrane coated α-zein biomimetic drug delivery system for the enhancement of homotypic target ability. INDUSTRIAL CROPS AND PRODUCTS, 194 (116301). [PMID:] |
28. Chen Cheng, Weixi Jiang, Yuanli Luo, Li Wan, Xun Guo, Zhuoyan Xie, Rui Tang, Tong Huang, Jingxue Wang, Chier Du, Zhigang Wang, Haitao Ran, Pan Li, Zhiyi Zhou, Jianli Ren. (2023) NIR Activated Multimodal Therapeutics Based on Metal–Phenolic Networks-Functionalized Nanoplatform for Combating against Multidrug Resistance and Metastasis. Small, 19 (14): (2206174). [PMID:36651135] |
29. Liang Chen, Yi Xu. (2023) Low temperature upregulating HSP70 expression to mitigate the paclitaxel-induced damages in NHEK cell. PeerJ, 11 (e14630). [PMID:36684674] |
30. Xun Guo, Peng Tu, Leilei Zhu, Chen Cheng, Weixi Jiang, Chier Du, Xiaoting Wang, Xiaoling Qiu, Yuanli Luo, Li Wan, Rui Tang, Haitao Ran, Zhigang Wang, Jianli Ren. (2023) Nanoenabled Tumor Energy Metabolism Disorder via Sonodynamic Therapy for Multidrug Resistance Reversal and Metastasis Inhibition. ACS Applied Materials & Interfaces, 15 (1): (309–326). [PMID:36576435] |
31. Li Huang, Huaqiang Fang, Teng Zhang, Binbin Hu, Shichen Liu, Fanzhen Lv, Zhaoxia Zeng, Huijie Liu, Weimin Zhou, Xiaolei Wang. (2023) Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment. Bioactive Materials, 23 (526). [PMID:36514389] |
32. Lianzhen Li, Ziqiang Shang, Jianfu Tang, Jiameng Li, Zefang Xiao, Yanjun Xie, Jiuqing Liu, Zhenjie Li, Shilong Yang, Yiqi Liu, Wentao Gan. (2022) Wood Robot with Magnetic Anisotropy for Programmable Locomotion. ADVANCED FUNCTIONAL MATERIALS, 33 (6): (2207209). [PMID:] |
33. Tong Gao, Xiao Sang, Xinyan Huang, Panpan Gu, Jie Liu, Yongjun Liu, Na Zhang. (2022) Macrophage-camouflaged epigenetic nanoinducers enhance chemoimmunotherapy in triple negative breast cancer. Acta Pharmaceutica Sinica B, [PMID:37799382] |
34. Hong Liu, Zhenfu Wen, Haolin Chen, Zeyu Yang, Zhicheng Le, Zhijia Liu, Yongming Chen, Lixin Liu. (2022) Nanoadjuvants Actively targeting lymph node conduits and blocking tumor invasion in lymphatic vessels. JOURNAL OF CONTROLLED RELEASE, 352 (497). [PMID:36341931] |
35. Jiayin Liu, Yang An, Jun Su, Qinghai Dong, Hongliu Xie, Jihua Liu. (2022) The antitumor activity and pharmacokinetics research of PPD-Arg (Tos) using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. BIOMEDICAL CHROMATOGRAPHY, 37 (2): (e5535). [PMID:36289571] |
36. ChengYu Deng, Rong Zhuang, ZhuoYang Ying, Jiasheng Tu, Xianghui Xu, Chunmeng Sun, Lei Jiang. (2022) Non-Invasive Transdermal Delivery Systems with Deep Tissue Penetrating Ability for Local ROS-Modulating Chemotherapy. ADVANCED FUNCTIONAL MATERIALS, 32 (46): (2206876). [PMID:] |
37. Xueting Tang, Lin Chen, Ziyu Wu, Yazhou Li, Jiaqi Zeng, Wentao Jiang, Wenzhi Lv, Mimi Wan, Chun Mao, Min Zhou. (2022) Lipophilic NO-Driven Nanomotors as Drug Balloon Coating for the Treatment of Atherosclerosis. Small, 19 (13): (2203238). [PMID:35961946] |
38. Tianyu Chen, Hui Chen, Yichun Jiang, Qi Yan, Shuling Zheng, Min Wu. (2022) Co-Delivery of 5-Fluorouracil and Paclitaxel in Mitochondria-Targeted KLA-Modified Liposomes to Improve Triple-Negative Breast Cancer Treatment. Pharmaceuticals, 15 (7): (881). [PMID:35890181] |
39. Chunyan Yang, Zhongzhen Yang, Siqi Wang, Jinxia Chen, Qijun Liu, Tianle Huang, Li Hai, Runxin Lu, Yong Wu. (2022) Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. BIOORGANIC & MEDICINAL CHEMISTRY, 69 (116893). [PMID:35752143] |
40. Chenglong Wang, Xiaolin Xu, Shuhan Xiong, Peipei Zhang, Jia Yuan, Xuzhu Gao, Wencai Guan, Fanchen Wang, Xin Li, Tao Leng, Hongjing Dou, Guoxiong Xu. (2022) Calcium-chelated nanosystem reversing cancer chemoresistance via replenishing intracellular calcium ions. CHEMICAL ENGINEERING JOURNAL, 448 (137500). [PMID:] |
41. Xiaowei Wang, Yanhong Liu, Yue Hu, Hong Gao, Meiling Ge, Jie Ding, Dongkai Wang. (2022) Hybrid micelles loaded with chemotherapeutic drug-photothermal agent realizing chemo-photothermal synergistic cancer therapy. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 175 (106231). [PMID:35671901] |
42. Yi Peng, Jie Pan, Fengting Ou, Wenchao Wang, Haihong Hu, Lu Chen, Su Zeng, Kui Zeng, Lushan Yu. (2022) Fenbendazole and its synthetic analog interfere with HeLa cells’ proliferation and energy metabolism via inducing oxidative stress and modulating MEK3/6-p38-MAPK pathway. CHEMICO-BIOLOGICAL INTERACTIONS, 361 (109983). [PMID:35569513] |
43. Xiao-Ling Wang, Wen-Zheng Zhao, Jia-Ze Fan, Le-Chen Jia, Ya-Nan Lu, Ling-Hui Zeng, Yuan-Yuan Lv, Xiao-Yi Sun. (2022) Tumor Tropic Delivery of Hyaluronic Acid-Poly (D,L-lactide-co-glycolide) Polymeric Micelles Using Mesenchymal Stem Cells for Glioma Therapy. MOLECULES, 27 (8): (2419). [PMID:35458619] |
44. Mingming Song, Shuqi Dong, Xiaofei An, Wenxiang Zhang, Ning Shen, Yanbo Li, Caixia Guo, Chang Liu, Xiao Li, Siyu Chen. (2022) Erythrocyte-biomimetic nanosystems to improve antitumor effects of paclitaxel on epithelial cancers. JOURNAL OF CONTROLLED RELEASE, 345 (744). [PMID:35381274] |
45. Yan Du, Li Lin, Zhong Zhang, Yu Tang, Xia Ou, Yaotai Wang, Jianzhong Zou. (2022) Drug-loaded nanoparticles conjugated with genetically engineered bacteria for cancer therapy. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 606 (29). [PMID:35338856] |
46. Huiru Zhu, Li Kong, Xu Zhu, Tingting Ran, Xiaojuan Ji. (2022) pH-Responsive Nanoparticles for Delivery of Paclitaxel to the Injury Site for Inhibiting Vascular Restenosis. Pharmaceutics, 14 (3): (535). [PMID:35335910] |
47. Beibei Zhang, Rui Xue, Chunyang Sun. (2022) Rational design of ROS-responsive nanocarriers for targeted X-ray-induced photodynamic therapy and cascaded chemotherapy of intracranial glioblastoma. Nanoscale, 14 (13): (5054-5067). [PMID:35293920] |
48. Xinling Xie, Youquan Zhang, Yong Zhu, Yiling Lan. (2022) Preparation and Drug-Loading Properties of Amphoteric Cassava Starch Nanoparticles. Nanomaterials, 12 (4): (598). [PMID:35214927] |
49. Chunjing Guo, Yanguo Su, Ziting Cheng, Qiang Chen, Huimin Guo, Ming Kong, Daquan Chen. (2022) Novel ROS-responsive marine biomaterial fucoidan nanocarriers with AIE effect and chemodynamic therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 202 (112). [PMID:35041879] |
50. Hao Li, Wenbo Xie, Lei Zeng, Wen Li, Boan Shi, Fuhou Lei. (2022) Development and evaluation of a hydrogenated rosin (β-acryloxyl ethyl) ester–bonded silica stationary phase for high-performance liquid chromatography separation of paclitaxel from yew bark. JOURNAL OF CHROMATOGRAPHY A, 1665 (462815). [PMID:35038614] |
51. Yangming-Fan, Jianjun-Ge. (2022) Pentoxifylline Prevents Restenosis by Inhibiting Cell Proliferation via p38MAPK Pathway in Rat Vein Graft Model.. CELL TRANSPLANTATION, 31 (9636897221122999-9636897221122999). [PMID:36066039] |
52. Haiqin Huang, Lanlan Shao, Yan Chen, Lan Tang, Tianqing Liu, Junxu Li, Hongyan Zhu. (2021) Synergistic strategy with hyperthermia therapy based immunotherapy and engineered exosomes−liposomes targeted chemotherapy prevents tumor recurrence and metastasis in advanced breast cancer. Bioengineering & Translational Medicine, 7 (2): (e10284). [PMID:35600651] |
53. Sushan Ouyang, Yi Zhang, Sheng Yao, Longbao Feng, Ping Li, Senlin Zhu. (2021) The efficiency of MSC-based targeted AIE nanoparticles for gastric cancer diagnosis and treatment: An experimental study. Bioengineering & Translational Medicine, 7 (2): (e10278). [PMID:35600644] |
54. Huan Zhang, Jinshun Xu, Binyang Gao, Hong Wang, Jianbo Huang, Jie Zhou, Rui Yang, Feng Yan, Yulan Peng. (2021) Synergistic Cascade Strategy Based on Modifying Tumor Microenvironment for Enhanced Breast Cancer Therapy. Frontiers in Pharmacology, 12 (750847). [PMID:34867360] |
55. Yuqiong Shi, Wei Liu, Xiangrong Wu, Jinhua Zhu, Danyang Zhou, Xiuhua Liu. (2021) A Water-Soluble Polyacid Polymer Based on Hydrophilic Metal–Organic Frameworks Using Amphoteric Carboxylic Acid Ligands as Linkers for Hydroxycamptothecin Loading and Release In Vitro. Nanomaterials, 11 (11): (2854). [PMID:34835619] |
56. Tian Chai, Yin Qiang. (2022) Two new coumarins from branches of Zanthoxylum schinifolium. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 24 (9): (820-826). [PMID:34662216] |
57. Rui Zhang, Ge Cheng, Shengnan Liu, Hongying Lv, Juan Li. (2021) A four-in-one pure nanomedicine for synergistic multi-target therapy against breast cancer. Journal of Materials Chemistry B, 9 (42): (8809-8822). [PMID:34633023] |
58. Yadong Tang,Boxin Huang,Yuqin Dong,Wenlong Wang,Xi Zheng,Wei Zhou,Kun Zhang,Zhiyun Du. (2017-06-07) Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy.. Journal of biomaterials science. Polymer edition, 28 ((14)): (1603-1616). [PMID:28583017] |
59. Lingling Wang,Xiuhua Zhao,Fengjian Yang,Weiwei Wu,Mingfang Wu,Yuanyuan Li,Xiaoxue Zhang. (2019-07-16) Loading paclitaxel into porous starch in the form of nanoparticles to improve its dissolution and bioavailability.. International journal of biological macromolecules, 138 (207-214). [PMID:31306708] |
60. Wanbing Qin,Guilan Quan,Ying Sun,Minglong Chen,Peipei Yang,Disang Feng,Ting Wen,Xinyu Hu,Xin Pan,Chuanbin Wu. (2020-07-30) Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma.. Theranostics, 10 ((18)): (8179-8196). [PMID:32724465] |
61. Xuejing Zhang,Shiwei Niu,Gareth R Williams,Jianrong Wu,Xia Chen,Hong Zheng,Li-Min Zhu. (2019-06-23) Dual-responsive nanoparticles based on chitosan for enhanced breast cancer therapy.. Carbohydrate polymers, 221 (84-93). [PMID:31227170] |
62. Li FF, Sun Q, Wang D, Liu S, Lin B, Liu CT, Li LZ, Huang XX, Song SJ.. (2016) Chiral Separation of Cytotoxic Flavan Derivatives from Daphne giraldii.. J Nat Prod, 79 (9): (2236-2242). [PMID:27627130] |
1. Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K, Nishijima M. (2000) Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol.. J Biol Chem, 275 (4): (2251-4). [PMID:10644670] |
2. Lee ST et al.. (2011) Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.. PLoS One, 6 (4): (e18915). [PMID:21541327] |
3. Wala K et al.. (2022) Anticancer Efficacy of 6-Gingerol with Paclitaxel against Wild Type of Human Breast Adenocarcinoma.. Molecules, 27 (9): [PMID:35566044] |
4. Rose JC et al.. (2018) Biofunctionalized aligned microgels provide 3D cell guidance to mimic complex tissue matrices.. Biomaterials, 163 (128-141). [PMID:29459322] |
5. Dong P et al.. (2013) Induction of paclitaxel resistance by ERa mediated prohibitin mitochondrial-nuclear shuttling.. PLoS One, 8 (12): (e83519). [PMID:24376711] |
6. Liu M et al.. (2021) Identification of a prognostic chemoresistance-related gene signature associated with immune microenvironment in breast cancer.. Bioengineered, 12 (8419-8434). [PMID:34661511] |
7. Lai SL et al.. (2012) In vitro and in vivo anti-angiogenic activities of Panduratin A.. PLoS One, 7 (5): (e38103). [PMID:22666456] |
8. Ferreira SA et al.. (2018) Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence.. Biomaterials, 176 (13-23). [PMID:29852376] |
9. Samanta J et al.. (2020) Oleic Acid Protects from Arsenic-Induced Cardiac Hypertrophy via AMPK/FoxO/NFATc3 Pathway.. Cardiovasc Toxicol, 20 (3): (261-280). [PMID:31571030] |
10. Yang Y et al.. (2016) Skp2 is associated with paclitaxel resistance in prostate cancer cells.. Oncol Rep, 36 (559-66). [PMID:27175797] |
11. Tran LNK et al.. (2017) The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer.. Mol Cancer Ther, 16 (12): (2689-2700). [PMID:28802253] |
12. Materazzi S et al.. (2012) TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.. Pflugers Arch, 463 (4): (561-9). [PMID:22258694] |
13. Meijia Zheng, Chenxi Zhou, Hong Liao, Qin Li, Alan Bao, Chunmei Chen, Feng He, Peng Wu, Weiguang Sun, Hucheng Zhu, Yonghui Zhang. (2024) Enantiomeric α-pyrone derivatives with immunosuppressive activity from Talaromyces adpressus. PHYTOCHEMISTRY, 218 (15): (113931). [PMID:38029950] |
14. Li Qiwei, Chen Zaozao, Zhang Ying, Ding Shuang, Ding Haibo, Wang Luping, Xie Zhuoying, Fu Yifu, Wei Mengxiao, Liu Shengnan, Chen Jialun, Wang Xuan, Gu Zhongze. (2023) Imaging cellular forces with photonic crystals. Nature Communications, 14 (1): (1-14). [PMID:37963911] |
15. Fang Chen, Li Yin, Teng He, Tao Chen, Hangbo Yue, Chufen Yang. (2023) Fabrication of Dual pH/Reduction-Responsive P(CL-co-ACL)-Based Cross-Linked Polymeric Micelles for PTX Delivery. LANGMUIR, 39 (46): (16358–16366). [PMID:37934563] |
16. Yiqian Zhang, Qianrui Huang, Qisi Xu, Chengsen Jia, Yong Xia. (2023) Pimavanserin tartrate induces apoptosis and cytoprotective autophagy and synergizes with chemotherapy on triple negative breast cancer. BIOMEDICINE & PHARMACOTHERAPY, 168 (8): (115665). [PMID:37832400] |
17. Chaoyao Geng, Jiaqi Niu, Dan Zhao, Xiaoxin Jin, Jiaojiao Liu, Xiaoqiang Liu, Danny K.Y. Wong. (2023) Evaluation of electrocatalysis of hourglass-shaped polyoxometallates with different transition metals towards hydrogen peroxide transformed from superoxide radicals in living cell mitochondria. CHEMICAL ENGINEERING JOURNAL, 475 (7): (146302). [PMID:21211617] |
18. Hao Wei, Yongxiang Luo, Ruisen Ma, Yuxiao Li. (2023) Three-Dimensional Printing Multi-Drug Delivery Core/Shell Fiber Systems with Designed Release Capability. Pharmaceutics, 15 (9): (2336). [PMID:37765304] |
19. Xinping Hu, Chuhang Zhou, Leqi Wang, Qi Liu, Yining Ma, Yingwei Tang, Xiaoxiao Wang, Kanghao Chen, Xinyu Wang, Yan Liu. (2023) Procedurally Targeted Delivery of Antitumor Drugs Using FAPα-Responsive TPGS Dimer-Based Flower-like Polymeric Micelles. ACS Applied Bio Materials, [PMID:37702706] |
20. Qi Nie, Wenqing Chen, Tianmei Zhang, Shangrong Ye, Zhongyu Ren, Peng Zhang, Jian Wen. (2023) Iron oxide nanoparticles induce ferroptosis via the autophagic pathway by synergistic bundling with paclitaxel. Molecular Medicine Reports, 28 (4): (1-13). [PMID:37681444] |
21. Hong Shen, Changwei Zhang, Chengzhang Wang, Jianxin Jiang, Fengxia Tang, Chuan Li, Hua Yuan, Xiaoran Yang, Zhenkai Tong, Yi Huang. (2023) Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy. ACS Omega, 8 (34): (31436–31449). [PMID:37663483] |
22. Yao Liu, Zhichao He, Heng Liang, Minzhen Han, Jinxingyi Wang, Qian Liu, Yanping Guan. (2023) A high-throughput UHPLC-MS/MS method for the determination of eight anti-tumor drugs in plasma. ANALYTICAL BIOCHEMISTRY, 676 (115230). [PMID:37429484] |
23. Fenglin Huang, Sisi Yang, Hao Wang, Peiwen Zhao, Bo Zhou, Bo Cheng, Siyan Dong, Jing Yang, Binbin Li, Xinyu Wang. (2023) pH-responsive PLGA/gelatin porous microspheres containing paclitaxel used for inhibition of cancer cell proliferation. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 86 (104735). [PMID:] |
24. Heming Zhao, Liming Gong, Hao Wu, Chao Liu, Yanhong Liu, Congcong Xiao, Chenfei Liu, Liqing Chen, Mingji Jin, Zhonggao Gao, Youyan Guan, Wei Huang. (2023) Development of Novel Paclitaxel-Loaded ZIF-8 Metal-Organic Framework Nanoparticles Modified with Peptide Dimers and an Evaluation of Its Inhibitory Effect against Prostate Cancer Cells. Pharmaceutics, 15 (7): (1874). [PMID:37514059] |
25. Shuncheng Yao, Shaobo Wang, Minjia Zheng, Zhuo Wang, Zhirong Liu, Zhong Lin Wang, Linlin Li. (2023) Implantable, Biodegradable, and Wireless Triboelectric Devices for Cancer Therapy Through Disrupting Microtubule and Actins Dynamics. ADVANCED MATERIALS, (2303962). [PMID:37392034] |
26. Deqian Qiao, Yiling Liu, Yunlong Lei, Chundong Zhang, Youquan Bu, Yishu Tang, Ying Zhang. (2023) rRNA-Derived Small RNA rsRNA-28S Regulates the Chemoresistance of Prostate Cancer Cells by Targeting PTGIS. Frontiers in Bioscience-Landmark, 28 (5): (102). [PMID:37258478] |
27. Qi Wenxia, Wang Shenglan, Yang Heng, Luo Tingting, Zhao Feng, Han Jingtian, Zhang Jing. (2023) An albumin-based nanosystem for cocktail therapy of breast cancer amplifies the therapeutic efficacy of combination chemotherapy with photodynamic therapy. JOURNAL OF MATERIALS SCIENCE, 58 (21): (8952-8968). [PMID:] |
28. Xinran Wang, Jieyi Pan, Haohui Shi, Na Liang, Shaoping Sun. (2023) Biotin-modified acid-sensitive micelles for enhancing antitumor effect of paclitaxel. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 84 (104538). [PMID:] |
29. Pingfu Huang, Hui Yan, Hao Wu, Lulu Liu, Wenmin Niu, Bo Zhai, Ziwei Hu, Jingjuan Li, Qianming Du, Yang Zhou. (2023) Application of curcumin as a co-former and an efflux inhibitor in paclitaxel co-amorphous mixture. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 84 (104513). [PMID:] |
30. Feng Gao, Xinmin Zhao, Qiankang Si, Xingkun Niu, Shaojie Hou, Shihao Liu, Jun Guo, Liping Wang, Feng Zhang. (2023) Gemini surfactant-like peptide-based nanocages with β-sheet-enhanced stability and encapsulation efficiency of hydrophobic anticancer drugs. RSC Advances, 13 (19): (12863-12868). [PMID:37114030] |
31. Changhai Wang, Yuwen Jiao, Xinyu Zhang, Mingxue Guo, Qing Zhang, Wenjun Hu, Shuang Dong, Tangthianchaichana Jakkree, Yang Lu, Jinling Wang. (2023) A paclitaxel prodrug nanoparticles with glutathion/reactive oxygen species dual-responsive and CD206 targeting to improve the anti-tumour effect. IET Nanobiotechnology, 17 (5): (406-419). [PMID:37055350] |
32. Chunjing Guo, Wei Zhang, Qiaoyun Zhang, Yanguo Su, Xiaoya Hou, Qiang Chen, Huimin Guo, Ming Kong, Daquan Chen. (2023) Novel dual CAFs and tumour cell targeting pH and ROS dual sensitive micelles for targeting delivery of paclitaxel to liver cancer. Artificial Cells Nanomedicine and Biotechnology, 51 (1): (170-179). [PMID:37014123] |
33. Jingshuai Wang, Xuemin Gu, Yiqin Ouyang, Lei Chu, Mengjiao Xu, Kun Wang, Xiaowen Tong. (2023) Engineering of Neutrophil Membrane Camouflaging Nanoparticles Realizes Targeted Drug Delivery for Amplified Antitumor Therapy. International Journal of Nanomedicine, [PMID:33623381] |
34. Yaqin Tu, Wei Zhang, Guorun Fan, Chenming Zou, Jie Zhang, Nan Wu, Jiahui Ding, Wen Qing Zou, Hongjun Xiao, Songwei Tan. (2023) Paclitaxel-loaded ROS-responsive nanoparticles for head and neck cancer therapy. DRUG DELIVERY, 30 (1): (2189106). [PMID:36916054] |
35. Zhou LiPing, Li JiaWei, Yu Bing, Zhang Jun, Hu Hao, Cong HaiLin, Shen YouQing. (2023) The drug loading behavior of PAMAM dendrimer: Insights from experimental and simulation study. Science China-Technological Sciences, 66 (4): (1129-1140). [PMID:] |
36. Asmaa S.A. Hammad, Mohamed M. Sayed-Ahmed, Sara Mohamed Naguib Abdel Hafez, Ahmed R.N. Ibrahim, Mohamed M.A. Khalifa, Mahmoud El-Daly. (2023) Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NF-κB and klotho protein expression. CHEMICO-BIOLOGICAL INTERACTIONS, 376 (110446). [PMID:36898573] |
37. Liu Fei, Xu Yanjun, Wang Li, Ma Xifeng, Zhang Zhen, Zhuang Xiaomei. (2023) Combined contributions of cytochrome P450s (CYPs) and non-enzymatic metabolism in the in vitro biotransformation of anaprazole, a novel proton pump inhibitor. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 396 (8): (1759-1771). [PMID:36847804] |
38. Yanzhao Jin, Jiaqing Cao, Hua Cheng, Xiaoyun Hu. (2023) LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma. JOURNAL OF CHEMOTHERAPY, [PMID:36797828] |
39. Wenquan Huang, Zhiqiang Li, Weiqi Liu, Shiyuan Liu, Rujin Zhou, Yanbin Jiang. (2023) Preparation of B16 cancer cell membrane coated α-zein biomimetic drug delivery system for the enhancement of homotypic target ability. INDUSTRIAL CROPS AND PRODUCTS, 194 (116301). [PMID:] |
40. Chen Cheng, Weixi Jiang, Yuanli Luo, Li Wan, Xun Guo, Zhuoyan Xie, Rui Tang, Tong Huang, Jingxue Wang, Chier Du, Zhigang Wang, Haitao Ran, Pan Li, Zhiyi Zhou, Jianli Ren. (2023) NIR Activated Multimodal Therapeutics Based on Metal–Phenolic Networks-Functionalized Nanoplatform for Combating against Multidrug Resistance and Metastasis. Small, 19 (14): (2206174). [PMID:36651135] |
41. Liang Chen, Yi Xu. (2023) Low temperature upregulating HSP70 expression to mitigate the paclitaxel-induced damages in NHEK cell. PeerJ, 11 (e14630). [PMID:36684674] |
42. Xun Guo, Peng Tu, Leilei Zhu, Chen Cheng, Weixi Jiang, Chier Du, Xiaoting Wang, Xiaoling Qiu, Yuanli Luo, Li Wan, Rui Tang, Haitao Ran, Zhigang Wang, Jianli Ren. (2023) Nanoenabled Tumor Energy Metabolism Disorder via Sonodynamic Therapy for Multidrug Resistance Reversal and Metastasis Inhibition. ACS Applied Materials & Interfaces, 15 (1): (309–326). [PMID:36576435] |
43. Li Huang, Huaqiang Fang, Teng Zhang, Binbin Hu, Shichen Liu, Fanzhen Lv, Zhaoxia Zeng, Huijie Liu, Weimin Zhou, Xiaolei Wang. (2023) Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment. Bioactive Materials, 23 (526). [PMID:36514389] |
44. Lianzhen Li, Ziqiang Shang, Jianfu Tang, Jiameng Li, Zefang Xiao, Yanjun Xie, Jiuqing Liu, Zhenjie Li, Shilong Yang, Yiqi Liu, Wentao Gan. (2022) Wood Robot with Magnetic Anisotropy for Programmable Locomotion. ADVANCED FUNCTIONAL MATERIALS, 33 (6): (2207209). [PMID:] |
45. Tong Gao, Xiao Sang, Xinyan Huang, Panpan Gu, Jie Liu, Yongjun Liu, Na Zhang. (2022) Macrophage-camouflaged epigenetic nanoinducers enhance chemoimmunotherapy in triple negative breast cancer. Acta Pharmaceutica Sinica B, [PMID:37799382] |
46. Hong Liu, Zhenfu Wen, Haolin Chen, Zeyu Yang, Zhicheng Le, Zhijia Liu, Yongming Chen, Lixin Liu. (2022) Nanoadjuvants Actively targeting lymph node conduits and blocking tumor invasion in lymphatic vessels. JOURNAL OF CONTROLLED RELEASE, 352 (497). [PMID:36341931] |
47. Jiayin Liu, Yang An, Jun Su, Qinghai Dong, Hongliu Xie, Jihua Liu. (2022) The antitumor activity and pharmacokinetics research of PPD-Arg (Tos) using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. BIOMEDICAL CHROMATOGRAPHY, 37 (2): (e5535). [PMID:36289571] |
48. ChengYu Deng, Rong Zhuang, ZhuoYang Ying, Jiasheng Tu, Xianghui Xu, Chunmeng Sun, Lei Jiang. (2022) Non-Invasive Transdermal Delivery Systems with Deep Tissue Penetrating Ability for Local ROS-Modulating Chemotherapy. ADVANCED FUNCTIONAL MATERIALS, 32 (46): (2206876). [PMID:] |
49. Xueting Tang, Lin Chen, Ziyu Wu, Yazhou Li, Jiaqi Zeng, Wentao Jiang, Wenzhi Lv, Mimi Wan, Chun Mao, Min Zhou. (2022) Lipophilic NO-Driven Nanomotors as Drug Balloon Coating for the Treatment of Atherosclerosis. Small, 19 (13): (2203238). [PMID:35961946] |
50. Tianyu Chen, Hui Chen, Yichun Jiang, Qi Yan, Shuling Zheng, Min Wu. (2022) Co-Delivery of 5-Fluorouracil and Paclitaxel in Mitochondria-Targeted KLA-Modified Liposomes to Improve Triple-Negative Breast Cancer Treatment. Pharmaceuticals, 15 (7): (881). [PMID:35890181] |
51. Chunyan Yang, Zhongzhen Yang, Siqi Wang, Jinxia Chen, Qijun Liu, Tianle Huang, Li Hai, Runxin Lu, Yong Wu. (2022) Berberine and folic acid co-modified pH-sensitive cascade-targeted PTX-liposomes coated with Tween 80 for treating glioma. BIOORGANIC & MEDICINAL CHEMISTRY, 69 (116893). [PMID:35752143] |
52. Chenglong Wang, Xiaolin Xu, Shuhan Xiong, Peipei Zhang, Jia Yuan, Xuzhu Gao, Wencai Guan, Fanchen Wang, Xin Li, Tao Leng, Hongjing Dou, Guoxiong Xu. (2022) Calcium-chelated nanosystem reversing cancer chemoresistance via replenishing intracellular calcium ions. CHEMICAL ENGINEERING JOURNAL, 448 (137500). [PMID:] |
53. Xiaowei Wang, Yanhong Liu, Yue Hu, Hong Gao, Meiling Ge, Jie Ding, Dongkai Wang. (2022) Hybrid micelles loaded with chemotherapeutic drug-photothermal agent realizing chemo-photothermal synergistic cancer therapy. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 175 (106231). [PMID:35671901] |
54. Yi Peng, Jie Pan, Fengting Ou, Wenchao Wang, Haihong Hu, Lu Chen, Su Zeng, Kui Zeng, Lushan Yu. (2022) Fenbendazole and its synthetic analog interfere with HeLa cells’ proliferation and energy metabolism via inducing oxidative stress and modulating MEK3/6-p38-MAPK pathway. CHEMICO-BIOLOGICAL INTERACTIONS, 361 (109983). [PMID:35569513] |
55. Xiao-Ling Wang, Wen-Zheng Zhao, Jia-Ze Fan, Le-Chen Jia, Ya-Nan Lu, Ling-Hui Zeng, Yuan-Yuan Lv, Xiao-Yi Sun. (2022) Tumor Tropic Delivery of Hyaluronic Acid-Poly (D,L-lactide-co-glycolide) Polymeric Micelles Using Mesenchymal Stem Cells for Glioma Therapy. MOLECULES, 27 (8): (2419). [PMID:35458619] |
56. Mingming Song, Shuqi Dong, Xiaofei An, Wenxiang Zhang, Ning Shen, Yanbo Li, Caixia Guo, Chang Liu, Xiao Li, Siyu Chen. (2022) Erythrocyte-biomimetic nanosystems to improve antitumor effects of paclitaxel on epithelial cancers. JOURNAL OF CONTROLLED RELEASE, 345 (744). [PMID:35381274] |
57. Yan Du, Li Lin, Zhong Zhang, Yu Tang, Xia Ou, Yaotai Wang, Jianzhong Zou. (2022) Drug-loaded nanoparticles conjugated with genetically engineered bacteria for cancer therapy. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 606 (29). [PMID:35338856] |
58. Huiru Zhu, Li Kong, Xu Zhu, Tingting Ran, Xiaojuan Ji. (2022) pH-Responsive Nanoparticles for Delivery of Paclitaxel to the Injury Site for Inhibiting Vascular Restenosis. Pharmaceutics, 14 (3): (535). [PMID:35335910] |
59. Beibei Zhang, Rui Xue, Chunyang Sun. (2022) Rational design of ROS-responsive nanocarriers for targeted X-ray-induced photodynamic therapy and cascaded chemotherapy of intracranial glioblastoma. Nanoscale, 14 (13): (5054-5067). [PMID:35293920] |
60. Xinling Xie, Youquan Zhang, Yong Zhu, Yiling Lan. (2022) Preparation and Drug-Loading Properties of Amphoteric Cassava Starch Nanoparticles. Nanomaterials, 12 (4): (598). [PMID:35214927] |
61. Chunjing Guo, Yanguo Su, Ziting Cheng, Qiang Chen, Huimin Guo, Ming Kong, Daquan Chen. (2022) Novel ROS-responsive marine biomaterial fucoidan nanocarriers with AIE effect and chemodynamic therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 202 (112). [PMID:35041879] |
62. Hao Li, Wenbo Xie, Lei Zeng, Wen Li, Boan Shi, Fuhou Lei. (2022) Development and evaluation of a hydrogenated rosin (β-acryloxyl ethyl) ester–bonded silica stationary phase for high-performance liquid chromatography separation of paclitaxel from yew bark. JOURNAL OF CHROMATOGRAPHY A, 1665 (462815). [PMID:35038614] |
63. Yangming-Fan, Jianjun-Ge. (2022) Pentoxifylline Prevents Restenosis by Inhibiting Cell Proliferation via p38MAPK Pathway in Rat Vein Graft Model.. CELL TRANSPLANTATION, 31 (9636897221122999-9636897221122999). [PMID:36066039] |
64. Haiqin Huang, Lanlan Shao, Yan Chen, Lan Tang, Tianqing Liu, Junxu Li, Hongyan Zhu. (2021) Synergistic strategy with hyperthermia therapy based immunotherapy and engineered exosomes−liposomes targeted chemotherapy prevents tumor recurrence and metastasis in advanced breast cancer. Bioengineering & Translational Medicine, 7 (2): (e10284). [PMID:35600651] |
65. Sushan Ouyang, Yi Zhang, Sheng Yao, Longbao Feng, Ping Li, Senlin Zhu. (2021) The efficiency of MSC-based targeted AIE nanoparticles for gastric cancer diagnosis and treatment: An experimental study. Bioengineering & Translational Medicine, 7 (2): (e10278). [PMID:35600644] |
66. Huan Zhang, Jinshun Xu, Binyang Gao, Hong Wang, Jianbo Huang, Jie Zhou, Rui Yang, Feng Yan, Yulan Peng. (2021) Synergistic Cascade Strategy Based on Modifying Tumor Microenvironment for Enhanced Breast Cancer Therapy. Frontiers in Pharmacology, 12 (750847). [PMID:34867360] |
67. Yuqiong Shi, Wei Liu, Xiangrong Wu, Jinhua Zhu, Danyang Zhou, Xiuhua Liu. (2021) A Water-Soluble Polyacid Polymer Based on Hydrophilic Metal–Organic Frameworks Using Amphoteric Carboxylic Acid Ligands as Linkers for Hydroxycamptothecin Loading and Release In Vitro. Nanomaterials, 11 (11): (2854). [PMID:34835619] |
68. Tian Chai, Yin Qiang. (2022) Two new coumarins from branches of Zanthoxylum schinifolium. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 24 (9): (820-826). [PMID:34662216] |
69. Rui Zhang, Ge Cheng, Shengnan Liu, Hongying Lv, Juan Li. (2021) A four-in-one pure nanomedicine for synergistic multi-target therapy against breast cancer. Journal of Materials Chemistry B, 9 (42): (8809-8822). [PMID:34633023] |
70. Yadong Tang,Boxin Huang,Yuqin Dong,Wenlong Wang,Xi Zheng,Wei Zhou,Kun Zhang,Zhiyun Du. (2017-06-07) Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy.. Journal of biomaterials science. Polymer edition, 28 ((14)): (1603-1616). [PMID:28583017] |
71. Lingling Wang,Xiuhua Zhao,Fengjian Yang,Weiwei Wu,Mingfang Wu,Yuanyuan Li,Xiaoxue Zhang. (2019-07-16) Loading paclitaxel into porous starch in the form of nanoparticles to improve its dissolution and bioavailability.. International journal of biological macromolecules, 138 (207-214). [PMID:31306708] |
72. Wanbing Qin,Guilan Quan,Ying Sun,Minglong Chen,Peipei Yang,Disang Feng,Ting Wen,Xinyu Hu,Xin Pan,Chuanbin Wu. (2020-07-30) Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma.. Theranostics, 10 ((18)): (8179-8196). [PMID:32724465] |
73. Xuejing Zhang,Shiwei Niu,Gareth R Williams,Jianrong Wu,Xia Chen,Hong Zheng,Li-Min Zhu. (2019-06-23) Dual-responsive nanoparticles based on chitosan for enhanced breast cancer therapy.. Carbohydrate polymers, 221 (84-93). [PMID:31227170] |
74. Li FF, Sun Q, Wang D, Liu S, Lin B, Liu CT, Li LZ, Huang XX, Song SJ.. (2016) Chiral Separation of Cytotoxic Flavan Derivatives from Daphne giraldii.. J Nat Prod, 79 (9): (2236-2242). [PMID:27627130] |