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Paeonol - 99%, high purity , CAS No.552-41-0

14 Citations

≥99%

CAS#: 552-41-0
Formula: C₉H₁₀O₃
Molecular Weight: 166.17
Beilstein Registry Number: 8267
EC Number: 209-012-2
MDL number: MFCD00008730
PubChem CID: 11092
PubChem SID: 488181255

Item Number

H111081

Grouped product items
SKU	Size	Availability	Price
H111081-1g	1g	In stock	$75.90
H111081-5g	5g	In stock	$342.90
H111081-10g	10g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$615.90
H111081-25g	25g	In stock	$1,385.90
H111081-100g	100g	In stock	$4,986.90
H111081-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$22,438.90

Potent anti-inflammatory and antioxidant agent

View related series

ketone Monoamine Oxidase Neuronal Signaling Non heterocyclic block

Basic Description

Synonyms	1-(2-hydroxy-4-methoxyphenyl)ethane-1-one \| AC-7982 \| AM20040702 \| HMS3656E07 \| PAEONOL [WHO-DD] \| SW219250-1 \| Z57101020 \| Q7124105 \| RESACETOPHENONE 4-O-METHYL ETHER \| NCGC00095977-03 \| CCG-39471 \| FT-0618875 \| PAEONOL \| 4-08-00-01793 (Beilstein Handboo
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Potent anti-inflammatory and antioxidant agent. Enhances endogenous antioxidant activity. Reduces Bax and Caspase-3 expression. Shows anti-ischemic, renal protective and cardioprotective effects in vivo. Orally active.
Shipped In	Normal
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Paeonol is an active ingredient isolated from Paeonia suffruticosa Andr. Its pharmacologic functions include antiaggregatory, anti-inflammatory and anti-ischemia reperfusion damage and anti-lipid peroxidation effects. An anti-inflammatory & anti-lipid peroxidation agent

Associated Targets(Human)

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

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CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)

Discover Target: CACNA1C

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AKR1B1 Tclin Aldose reductase (1404 Activities)

Discover Target: AKR1B1

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

M14 (47487 Activities)

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MCF7 (126967 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

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Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

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Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488181255
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488181255
IUPAC Name	1-(2-hydroxy-4-methoxyphenyl)ethanone
INCHI	InChI=1S/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H3
InChi Key	UILPJVPSNHJFIK-UHFFFAOYSA-N
Canonical SMILES	CC(=O)C1=C(C=C(C=C1)OC)O
Isomeric SMILES	CC(=O)C1=C(C=C(C=C1)OC)O
WGK Germany	3
RTECS	RT1215000
PubChem CID	11092
Molecular Weight	166.17
Beilstein	8267
Reaxy-Rn	1282794

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot Number	Certificate Type	Date	Item
L2107549	Certificate of Analysis	Sep 20, 2023	H111081
L2107548	Certificate of Analysis	Sep 20, 2023	H111081
L2107547	Certificate of Analysis	Sep 20, 2023	H111081
L2107523	Certificate of Analysis	Sep 20, 2023	H111081
E1802021	Certificate of Analysis	Sep 06, 2023	H111081
E1802020	Certificate of Analysis	Sep 06, 2023	H111081
C1610281	Certificate of Analysis	Jun 06, 2023	H111081
E2112323	Certificate of Analysis	Feb 10, 2023	H111081
E2112325	Certificate of Analysis	Feb 10, 2023	H111081
E2223168	Certificate of Analysis	May 25, 2022	H111081
G2319512	Certificate of Analysis	May 25, 2022	H111081
G2319480	Certificate of Analysis	May 25, 2022	H111081
E2223165	Certificate of Analysis	May 25, 2022	H111081
E2223164	Certificate of Analysis	May 25, 2022	H111081
E2223161	Certificate of Analysis	May 25, 2022	H111081
G2024096	Certificate of Analysis	May 09, 2022	H111081
G2319494	Certificate of Analysis	Dec 14, 2021	H111081
D2314557	Certificate of Analysis	Dec 14, 2021	H111081

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Chemical and Physical Properties

Solubility	Soluble in water (<1 mg/ml at 25 °C), methanol, DMSO (33 mg/ml at 25 °C), and ethanol (33 mg/ml at 25 °C).
Refractive Index	1.54
Flash Point(°F)	235.4 °F
Flash Point(°C)	113 °C
Boil Point(°C)	154°C/20mmHg
Melt Point(°C)	47-50°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	RT1215000
Reaxy-Rn	1282794

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Chen Chen, Xiao Yang, Xian-hui Shao, Yue Zhou, Xiao-bin Zhang, Yun-ping Lu, Meng-zhen Xing, Qing-chang Xia, Yuan-xiang Liu, Yu-ning Ma, Ting-ting Zheng, Lin-lin Zhang, Yu-xia Ma, Ji-guo Yang. (2023) Thermal-grinding supramolecular network loaded with paeonol for treatment of skin eczema. CHEMICAL ENGINEERING SCIENCE, 281 (119096). [PMID:] [10.1016/j.ces.2023.119096]
2. Xin Li, Huimei Shi, Di Zhang, Bei Jing, Zhenni Chen, Yachun Zheng, Shiquan Chang, Li Gao, Guoping Zhao. (2023) Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway. CNS Neuroscience & Therapeutics, [PMID:37032648] [10.1111/cns.14211]
3. Shuai Liu, Keming Zheng, Yilin Jiang, Susu Gai, Bohan Li, Dehai Li, Shuang Yang, Zhihua Lv. (2023) Biotransformation of Penindolone, an Influenza A Virus Inhibitor. MOLECULES, 28 (3): (1479). [PMID:36771146] [10.3390/molecules28031479]
4. Songjun Liu, Xinran Cao, Tao Zhang, Chenyang Zhang, Jiao Qu, Yang Sun, Wen Lv, Fan Qu. (2023) Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis. PHYTOMEDICINE, 109 (154593). [PMID:36610113] [10.1016/j.phymed.2022.154593]
5. Siying Wang, Lanlan Xie, Qilei Yang, Yuting Geng, Hedi Kang, Xiuhua Zhao. (2022) Extraction and purification of paeonol from Moutan Cortex by a combined method of steam distillation and antisolvent recrystallization to reduce energy consumption and carbon dioxide emissions. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 101 (7): (3771-3785). [PMID:] [10.1002/cjce.24732]
6. Yuling Wang, Zeyan Tang, Xueping Guo, Yuqi Zhao, Shujing Ren, Zhenhai Zhang, Huixia Lv. (2022) Hyaluronic acid-cyclodextrin encapsulating paeonol for treatment of atopic dermatitis. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 623 (121916). [PMID:35714817] [10.1016/j.ijpharm.2022.121916]
7. Zhiping Che, Xiaolong Guo, Yuanhao Li, Song Zhang, Lina Zhu, Jiaxuan He, Di Sun, Yihao Guo, Yibo Liu, Ruxue Wei, Xiaobo Huang, Shengming Liu, Genqiang Chen, Yuee Tian. (2022) Synthesis of paeonol ester derivatives and their insecticidal, nematicidal, and anti-oomycete activities. PEST MANAGEMENT SCIENCE, 78 (8): (3442-3455). [PMID:35567371] [10.1002/ps.6985]
8. Yipeng Gu, Kai Chen, Bingwen Xi, Jun Xie, Xuwen Bing. (2022) Paeonol increases the antioxidant and anti-inflammatory capacity of gibel carp (Carassius auratus gibelio) challenged with Aeromonas hydrophila. FISH & SHELLFISH IMMUNOLOGY, 123 (479). [PMID:35314333] [10.1016/j.fsi.2022.03.005]
9. Yue-E Tian, Di Sun, Xiao-Xiao Han, Jin-Ming Yang, Song Zhang, Nan-Nan Feng, Li-Na Zhu, Zhong-Yuan Xu, Zhi-Ping Che, Sheng-Ming Liu, Xiao-Min Lin, Jia Jiang, Gen-Qiang Chen. (2021) Synthesis, anti-oomycete activity, and SAR studies of paeonol derivatives. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, [PMID:32009450] [10.1080/10286020.2020.1718116]
10. Chunqing Niu, Xiang Li, Yiyu Wang, Xinyu Liu, Jian Shi, Xinyu Wang. (2019) Design and performance of a poly(vinyl alcohol)/silk fibroin enzymatically crosslinked semi-interpenetrating hydrogel for a potential hydrophobic drug delivery. RSC Advances, 9 (70): (41074-41082). [PMID:35540084] [10.1039/C9RA09344C]
11. Jingjing Yao, Yangxin Zhang, Qiming Hu, Decheng Zeng, Fang Hua, Wei Meng, Weiyun Wang, Guan-Hu Bao. (2017) Optimization of paeonol-loaded poly(butyl-2-cyanoacrylate) nanocapsules by central composite design with response surface methodology together with the antibacterial properties. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 101 (189). [PMID:28189814] [10.1016/j.ejps.2017.01.028]
12. Jingjing Yao, Decheng Zeng, Yangxin Zhang, Dongdong Sun, Endong Yang, Haiping Liu, Feng Guo, Weiyun Wang. (2017) Effect of solvents on forming poly(butyl-2-cyanoacrylate) encapsulated paeonol nanocapsules. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 28 (3): (240-256). [PMID:27846779] [10.1080/09205063.2016.1262161]
13. Xie Xiaoyu, Pan Xiaoyan, Han Shengli, Wang Sicen. (2015) Development and characterization of magnetic molecularly imprinted polymers for the selective enrichment of endocrine disrupting chemicals in water and milk samples. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407 (6): (1735-1744). [PMID:25577356] [10.1007/s00216-014-8425-0]
14. Ping Mao, Xiao Wei, Mo Liqian, Xiao Xiaoyan, Song Shaolian, Tang Waijiao, Yang Xixiao. (2014) Paeonol Attenuates Advanced Oxidation Protein Product-Induced Oxidative Stress Injury in THP-1 Macrophages. PHARMACOLOGY, 93 (5-6): (286-295). [PMID:25170865] [10.1159/000363577]

References

1. Maofu Luo,Qi Shen,Jinjin Chen. (2011-09-10) Transdermal delivery of paeonol using cubic gel and microemulsion gel.. International journal of nanomedicine, 6 (1603-1610). [PMID:21904450]
2. Xiao-Jun Li,Xin-Wei Shi,Qi Shuai,Jin-Ming Gao,An-Ling Zhang. (2011-09-20) Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor.. Natural product communications, 6 ((8)): (1129-1130). [PMID:21922916]
3. Yu-Ting Tseng,Ya-Yun Hsu,Yu-Tzu Shih,Yi-Ching Lo. (2011-11-18) Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons.. Shock (Augusta, Ga.), 37 ((3)): (312-318). [PMID:22089194]
4. Tongyan Wang,Qihua Cui,Qingri Cao,Jinghao Cui. (2012-02-09) [Preparation of paeonol-beta-cyclodextrin inclusion complex loaded colon specific delivery tablets].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36 ((21)): (2956-2959). [PMID:22308682]
5. Ji-Yong Liu,Ying Han,Jin-Hong Hu,Zheng-Tao Wang,Kai-Xian Chen. (2012-04-19) [The preparation of paeonol transdermal delivery systems based on the microemulsion-based gels and its pharmacokinetics characters].. Yao xue xue bao = Acta pharmaceutica Sinica, 47 ((2)): (244-249). [PMID:22512039]
6. S W A Himaya,BoMi Ryu,Zhong-Ji Qian,Se-Kwon Kim. (2012-05-01) Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways.. Toxicology in vitro : an international journal published in association with BIBRA, 26 ((6)): (878-887). [PMID:22542583]
7. Liqin Ding,Zhaoxi Liu,Feng Zhao,Gang Bai,Lixia Chen,Xinsheng Yao,Feng Qiu. (2012-06-12) Isolation and identification of the metabolites of paeonol in human urine.. Xenobiotica; the fate of foreign compounds in biological systems, 42 ((12)): (1206-1212). [PMID:22680310]
8. Fei Yi,Chunhua Zou,Qiongbo Hu,Meiying Hu. (2012-06-20) The joint action of destruxins and botanical insecticides (rotenone, azadirachtin and paeonolum) against the cotton aphid, Aphis gossypii Glover.. Molecules (Basel, Switzerland), 17 ((6)): (7533-7542). [PMID:22710827]
9. Shiguang Sun,Mingqi Qiao,Huiyun Zhang. (2012-07-12) [Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36 ((11)): (1508-1511). [PMID:22779188]
10. Qing-qing Shan,Yu-ping Gong,Yong Guo,Juan Lin,Rui-qing Zhou,Xi Yang. (2012-07-21) [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 43 ((3)): (362-366). [PMID:22812238]
11. Rui-guang Wu,Jun-dong Dai,Fu-gen Wu,Xiao-hua Zhang,Wei-heng Li,Yu-rong Wang. (2012-09-18) Competitive molecular interaction among paeonol-loaded liposomes: differential scanning calorimetry and synchrotron X-ray diffraction studies.. International journal of pharmaceutics, 438 ((1-2)): (91-97). [PMID:22981687]
12. Hua Li,Yan-Hua Xie,Qian Yang,Si-Wang Wang,Bang-Le Zhang,Jian-Bo Wang,Wei Cao,Lin-Lin Bi,Ji-Yuan Sun,Shan Miao,Jing Hu,Xuan-Xuan Zhou,Peng-Cheng Qiu. (2012-11-10) Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats.. PloS one, 7 ((11)): (e48872-e48872). [PMID:23139821]
13. Quan-Jiang Long,Xiao-Ge Wang,Zhou Zhou,Bo Zhao. (2012-12-15) [Study on the influence of the contents of paeonol in the cutting process of fresh Cortex Moutan].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35 ((6)): (883-886). [PMID:23236819]
14. Mei-Hua Bao,Yi-Wen Zhang,Hong-Hao Zhou. (2013-01-30) Paeonol suppresses oxidized low-density lipoprotein induced endothelial cell apoptosis via activation of LOX-1/p38MAPK/NF-κB pathway.. Journal of ethnopharmacology, 146 ((2)): (543-551). [PMID:23357312]
15. Hua Li,Siwang Wang,Yanhua Xie,Bangle Zhang,Jianbo Wang,Qian Yang,Wei Cao. (2013-03-22) Simultaneous determination of danshensu, salvianolic acid B, and paeonol in ShuangDan oral liquid by HPLC.. Journal of AOAC International, 96 ((1)): (20-23). [PMID:23513951]
16. Li-Hua Peng,Shuai Liu,Shen-Yao Xu,Lei Chen,Ying-Hui Shan,Wei Wei,Wen-Quan Liang,Jian-Qing Gao. (2013-06-12) Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B-induced pigmentation in guinea pig skin.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 20 ((12)): (1082-1087). [PMID:23746955]
17. Chien-Shan Cheng,Jing-Xian Chen,Jian Tang,Ya-Wen Geng,Lan Zheng,Ling-Ling Lv,Lian-Yu Chen,Zhen Chen. (2020-02-27) Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition.. Cancer management and research, 12 (641-651). [PMID:32099461]
18. Hua Li,Siwang Wang,Bangle Zhang,Yanhua Xie,Jianbo Wang,Qian Yang,Wei Cao,Jing Hu,Linrui Duan. (2011-10-12) Influence of co-administered danshensu on pharmacokinetic fate and tissue distribution of paeonol in rats.. Planta medica, 78 ((2)): (135-140). [PMID:21986818]
19. Dan Wu,Guizhen Ao,Qingri Cao,Dawei Chen,Jinghao Cui. (2011-12-27) In vitro and in vivo evaluation of ibuprofen-paeonol conjugate.. Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1 (e98-100). [PMID:22195956]
20. Feng Qin,Jun Huang,Xinjian Qiu,Sihang Hu,Xi Huang. (2012-02-11) Quality control of modified xiaoyao san through the determination of 22 active components by ultra-performance liquid chromatography.. Journal of AOAC International, 94 ((6)): (1778-1784). [PMID:22320084]
21. Jong-Jen Kuo,Chih-Yang Wang,Ting-Fang Lee,Yi-Tsau Huang,Yun-Lian Lin. (2012-03-09) Paeoniae radix reduces PDGF-stimulated hepatic stellate cell migration.. Planta medica, 78 ((4)): (341-348). [PMID:22399273]
22. Xue-Jun Wang,Jian-Li Liu,Jiang-Kai Wang. (2012-04-12) [Synthesis and anti-tumor activity of paeonol and its derivatives].. Yao xue xue bao = Acta pharmaceutica Sinica, 47 ((1)): (72-76). [PMID:22493808]
23. Bendong Chen,Mingliang Ning,Guangshun Yang. (2012-04-24) Effect of paeonol on antioxidant and immune regulatory activity in hepatocellular carcinoma rats.. Molecules (Basel, Switzerland), 17 ((4)): (4672-4683). [PMID:22522397]
24. Yue-Qin Wang,Min Dai,Ji-Chang Zhong,Deng-Ke Yin. (2012-06-13) Paeonol inhibits oxidized low density lipoprotein-induced monocyte adhesion to vascular endothelial cells by inhibiting the mitogen activated protein kinase pathway.. Biological & pharmaceutical bulletin, 35 ((5)): (767-772). [PMID:22687414]
25. Qiuling Wang,Wenquan Wang,Shengli Wei,Fulai Yu,Fang Peng,Yuqiang Fang. (2012-07-17) [Study on effect of different processing methods on seven main chemical components of wild and cultivated Paeonia lactiflora].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37 ((7)): (920-924). [PMID:22792789]
26. Jun Shi,Fang Wang,Xi-feng Teng,Si-hang Huang. (2012-12-12) [Study on stability and cutaneous permeation kinetics in vitro of positive-ionized liposome gel containing paeonol].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35 ((5)): (803-807). [PMID:23213746]
27. Shu-zhi Zhong,Shi-ping Ma,Quan-hai Wang,Zong-yuan Hong. (2012-12-15) [Protective effect of paeonol on neurotoxicity induced by Abeta1-42 and underlying mechanisms].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37 ((17)): (2603-2606). [PMID:23236760]
28. Yu Lei,Hong-Xia Li,Wen-Sen Jin,Wan-Ren Peng,Cong-Jun Zhang,Li-Jia Bu,Ying-Ying Du,Tai Ma,Guo-Ping Sun. (2013-07-24) The radiosensitizing effect of Paeonol on lung adenocarcinoma by augmentation of radiation-induced apoptosis and inhibition of the PI3K/Akt pathway.. International journal of radiation biology, 89 ((12)): (1079-1086). [PMID:23875954]
29. Likun Gao,Zhi Wang,Danhua Lu,Jinling Huang,Jin Liu,Li Hong. (2019-08-14) Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells.. Cell death & disease, 10 ((8)): (609-609). [PMID:31406198]
30. Chen Chen, Xiao Yang, Xian-hui Shao, Yue Zhou, Xiao-bin Zhang, Yun-ping Lu, Meng-zhen Xing, Qing-chang Xia, Yuan-xiang Liu, Yu-ning Ma, Ting-ting Zheng, Lin-lin Zhang, Yu-xia Ma, Ji-guo Yang. (2023) Thermal-grinding supramolecular network loaded with paeonol for treatment of skin eczema. CHEMICAL ENGINEERING SCIENCE, 281 (119096). [PMID:] [10.1016/j.ces.2023.119096]
31. Xin Li, Huimei Shi, Di Zhang, Bei Jing, Zhenni Chen, Yachun Zheng, Shiquan Chang, Li Gao, Guoping Zhao. (2023) Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway. CNS Neuroscience & Therapeutics, [PMID:37032648] [10.1111/cns.14211]
32. Shuai Liu, Keming Zheng, Yilin Jiang, Susu Gai, Bohan Li, Dehai Li, Shuang Yang, Zhihua Lv. (2023) Biotransformation of Penindolone, an Influenza A Virus Inhibitor. MOLECULES, 28 (3): (1479). [PMID:36771146] [10.3390/molecules28031479]
33. Songjun Liu, Xinran Cao, Tao Zhang, Chenyang Zhang, Jiao Qu, Yang Sun, Wen Lv, Fan Qu. (2023) Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis. PHYTOMEDICINE, 109 (154593). [PMID:36610113] [10.1016/j.phymed.2022.154593]
34. Siying Wang, Lanlan Xie, Qilei Yang, Yuting Geng, Hedi Kang, Xiuhua Zhao. (2022) Extraction and purification of paeonol from Moutan Cortex by a combined method of steam distillation and antisolvent recrystallization to reduce energy consumption and carbon dioxide emissions. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 101 (7): (3771-3785). [PMID:] [10.1002/cjce.24732]
35. Yuling Wang, Zeyan Tang, Xueping Guo, Yuqi Zhao, Shujing Ren, Zhenhai Zhang, Huixia Lv. (2022) Hyaluronic acid-cyclodextrin encapsulating paeonol for treatment of atopic dermatitis. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 623 (121916). [PMID:35714817] [10.1016/j.ijpharm.2022.121916]
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