Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant. Pancuronium dibromide interrupts neuromuscular transmission by competing with acetylcholine for receptor sites on the motor end-plate. Pancuroni
Storage Temp
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
Grade
Moligand™
Action Type
ANTAGONIST
Mechanism of action
Antagonist of nicotinic acetylcholine receptor α1 subunit
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Pancuronium dibromide is a competitive acetylcholine antagonist with an IC50 of 5.5 nM. A nicotine neuromuscular antagonist.
1.Haifeng Yao, Yahui Zhang, Yongping Dong, Mingfu Ye. (2023) Inhibiting effect of graphdiyne on Ru(bpy)32+ ECL and its application in drug detection based on the host–guest interaction of cucurbit[8]uril. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 950 (1):(117868). [PMID:7781595]
References
1.Haifeng Yao, Yahui Zhang, Yongping Dong, Mingfu Ye. (2023) Inhibiting effect of graphdiyne on Ru(bpy)32+ ECL and its application in drug detection based on the host–guest interaction of cucurbit[8]uril. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 950 (1):(117868). [PMID:7781595]
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