Paricalcitol - ≥99%, high purity , Vitamin D receptor agonist, CAS No.131918-61-1, Vitamin D receptor agonist

Item Number
P126516
Grouped product items
SKUSizeAvailabilityPrice Qty
P126516-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$190.90
P126516-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$859.90
P126516-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,546.90

Analog of the active form of vitamin D2

View related series
Vitamin D receptor Agonist

Basic Description

SynonymsPARICALCITOL [USP IMPURITY] | Zemplar (TN) | (1alpha,3beta,7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol | NCGC00182706-01 | PARICALCITOL [VANDF] | DB00910 | EX-A4434 | UNII-6702D36OG5 | (1R,3R,7E)-17beta-((2R,3E,5S)-6-hydroxy-5,6-dimethylhep
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsAnalog of the active form of vitamin D2; activates the vitamin D receptor.
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionVitamin D receptor agonist

Product Properties

ALogP5

Associated Targets(Human)

VDR Tclin Vitamin D3 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol
INCHI InChI=1S/C27H44O3/c1-18(8-9-19(2)26(3,4)30)24-12-13-25-21(7-6-14-27(24,25)5)11-10-20-15-22(28)17-23(29)16-20/h8-11,18-19,22-25,28-30H,6-7,12-17H2,1-5H3/b9-8+,21-11+/t18-,19+,22-,23-,24-,25+,27-/m1/s1
InChi Key BPKAHTKRCLCHEA-UBFJEZKGSA-N
Canonical SMILES CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C
Isomeric SMILES C[C@H](/C=C/[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C3C[C@H](C[C@@H](C3)O)O)C
PubChem CID 5281104
Molecular Weight 416.64

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
G2203322Certificate of AnalysisApr 07, 2024 P126516
G2203323Certificate of AnalysisApr 07, 2024 P126516
G2203402Certificate of AnalysisApr 07, 2024 P126516

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 2.08, Max Conc. mM: 5
SensitivityLight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H311:Toxic in contact with skin

H351:Suspected of causing cancer

H300:Fatal if swallowed

H330:Fatal if inhaled

H372:Causes damage to organs through prolonged or repeated exposure

H361:Suspected of damaging fertility or the unborn child

H301+H311:Toxic if swallowed or in contact with skin

H362:May cause harm to breast-fed children

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P330:Rinse mouth.

P320:Specific treatment is urgent (see ... on this label).

P263:Avoid contact during pregnancy/while nursing.

P361+P364:Take off immediately all contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

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