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Pazufloxacin - 98%, high purity , DNA topoisomerase II inhibitor, CAS No.127045-41-4, DNA topoisomerase II inhibitor
Basic Description Synonyms Pazufloxacin|127045-41-4|T-3761|Pazufloxacin [INN]|127046-18-8|4CZ1R38NDI|DTXSID5046697|NCGC00167534-01|(-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid|(2S)-6-(1-aminocyclopropyl)- Specifications & Purity Moligand™, ≥98% Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type INHIBITOR Mechanism of action DNA topoisomerase II inhibitor
Names and Identifiers IUPAC Name (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid INCHI InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1 InChi Key XAGMUUZPGZWTRP-ZETCQYMHSA-N Canonical SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O Isomeric SMILES C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O PubChem CID 65957 Molecular Weight 318.31
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H312: Harmful in contact with skin
H332: Harmful if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
P317: Get emergency medical help.
References 1. Muratani T, Inoue M, Mitsuhashi S. (1992) In vitro activity of T-3761, a new fluoroquinolone.. Antimicrob Agents Chemother, 36 (10): (2293-303). [PMID:1332594 ] 2. Fukuoka Y, Ikeda Y, Yamashiro Y, Takahata M, Todo Y, Narita H. (1993) In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.. Antimicrob Agents Chemother, 37 (3): (384-92). [PMID:8460909 ]
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