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PD 151746 - 95%, high purity , CAS No.179461-52-0

≥95%

CAS#: 179461-52-0
Formula: C₁₁H₈FNO₂S
Molecular Weight: 237.25
PubChem CID: 5353866

Item Number

P276048

Grouped product items
SKU	Size	Availability	Price
P276048-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$55.90
P276048-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$178.90
P276048-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$284.90
P276048-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$455.90

Cell permeable, selective, non-peptidic calpain inhibitor

Basic Description

Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Cell permeable, selective, non-peptidic calpain inhibitor (K i values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca 2+ calpain sites.
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Note	Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Associated Targets(Human)

CAPN1 Tchem Calpain-1 catalytic subunit (1 Activities)

Discover Target: CAPN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CAPN2 Tchem Calpain 2 (185 Activities)

Discover Target: CAPN2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid
INCHI	InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
InChi Key	HWMQHECFXSVZGN-KMKOMSMNSA-N
Canonical SMILES	C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S
Isomeric SMILES	C1=CC2=C(C=C1F)C(=CN2)/C=C(/C(=O)O)\S
WGK Germany	3
PubChem CID	5353866
Molecular Weight	237.25

Certificates

Certificate of Analysis(COA)

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8 results found

Lot Number	Certificate Type	Date	Item
G2402290	Certificate of Analysis	Mar 06, 2024	P276048
G2408173	Certificate of Analysis	Mar 06, 2024	P276048
G2408174	Certificate of Analysis	Mar 06, 2024	P276048
G2408225	Certificate of Analysis	Mar 06, 2024	P276048
G2408230	Certificate of Analysis	Mar 06, 2024	P276048
G2408231	Certificate of Analysis	Mar 06, 2024	P276048
G2408232	Certificate of Analysis	Mar 06, 2024	P276048
G2408234	Certificate of Analysis	Mar 06, 2024	P276048

Solubility

Soluble in DMSO to 100 mM

Sensitivity

air and light sensitive

WGK Germany

RIDADR

NONHforallmodesoftransport

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PD 151746 - 95%, high purity , CAS No.179461-52-0

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

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Solution Calculators

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