PD 151746 - 10mM in DMSO, high purity , CAS No.179461-52-0

  • 10mM in DMSO
Item Number
P422187
Grouped product items
SKUSizeAvailabilityPrice Qty
P422187-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$210.90

Cell permeable, selective, non-peptidic calpain inhibitor

Basic Description

Synonyms3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoicacid
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsCell permeable, selective, non-peptidic calpain inhibitor (K i values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca 2+ calpain sites.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

CAPN1 Tchem Calpain-1 catalytic subunit (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CAPN2 Tchem Calpain 2 (185 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

CAPN1 Calpain 1 (219 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid
INCHI InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
InChi Key HWMQHECFXSVZGN-KMKOMSMNSA-N
Canonical SMILES C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S
Isomeric SMILES C1=CC2=C(C=C1F)C(=CN2)/C=C(/C(=O)O)\S
WGK Germany 3
PubChem CID 5353866
Molecular Weight 237.25

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Sensitivityair and light sensitive

Safety and Hazards(GHS)

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

Solution Calculators