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PD 151746 - 10mM in DMSO, high purity , CAS No.179461-52-0
Cell permeable, selective, non-peptidic calpain inhibitor
Basic Description Synonyms 3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoicacid Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Cell permeable, selective, non-peptidic calpain inhibitor (K i values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca 2+ calpain sites. Storage Temp Protected from light,Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid INCHI InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3- InChi Key HWMQHECFXSVZGN-KMKOMSMNSA-N Canonical SMILES C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S Isomeric SMILES C1=CC2=C(C=C1F)C(=CN2)/C=C(/C(=O)O)\S WGK Germany 3 PubChem CID 5353866 Molecular Weight 237.25
Chemical and Physical Properties Sensitivity air and light sensitive
Safety and Hazards(GHS) WGK Germany 3 RIDADR NONHforallmodesoftransport
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