PD-161570 - ≥98%(HPLC), high purity , CAS No.192705-80-9

Item Number

P135784

• Synonyms: 192705-80-9 | PD 161570 | PD-161570 | pd161570 | N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea | CHEMBL45827 | 1-tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-(diethylamino)butylamino]pyrido[2,3-d]pyrimi
• Specifications & Purity: ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Selective FGFR inhibitor (IC50values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor phosphorylation (IC50= 622 nM) and growth of A121 cellsin vitro.
• Storage Temp: Store at 2-8°C,Argon charged
• Shipped In: Wet ice

Product Description

PD-161570 is a selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). PD 161570 inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro.
PD-161570 is a selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). PD 161570 inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro.
A selective FGFR inhibitor