PD-L1 Mouse mAb - Primary antibody, specific to PD-L1, Mouse IgG2b

    Application:
  • Flow Cytometry
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG2b
  • Clone Number: 29E.2A3
  • Conjugation: Unconjugated
Item Number
Ab121011
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab121011-10μg
10μg
In stock
$16.90
Ab121011-50μg
50μg
In stock
$49.90
Ab121011-100μg
100μg
In stock
$79.90
Ab121011-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90

mAb (29E.2A3); Mouse anti Human PD-L1 Antibody; Flow; Unconjugated

Basic Description

Product NamePD-L1 Mouse mAb - Primary antibody, specific to PD-L1, Mouse IgG2b
SynonymsAvelumab | B7-H | B7H1 | B7-H1 | B7H1PDCD1L1 | CD274 antigenMGC142294 | CD274 molecule | CD274 | PDCD1L1 | PDCD1LG1 | PDCD1LG1MGC142296 | PDL1 | PD-L1 | PD-L1B7 homolog 1 | PDL1PDCD1 ligand 1 | programmed cell death 1 ligand 1 | Programmed death ligand 1
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot
Host speciesMouse
SpecificityPD-L1
ImmunogenFull length human PD-L1
Positive ControlFlow: Stimulate human PBMC with PHA
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human PD-L1 Antibody, Monoclonal (29E.2A3), could be used for Flow and so on.
Application:
Flow: 0.06 μg/100w cells
Protein Function
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Product Properties

IsotypeMouse IgG2b
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Upon delivery aliquot.

Images

PD-L1 Mouse mAb (Ab121011) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-L1 (red) with PD-L1 Mouse mAb (Ab121011) at 0.1 μg/mL for 1 hour at 4°C. Goat anti Mouse IgG H&L(PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets(Human)

CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
Flow Cytometry

0.06 μg/100w cells

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404688Certificate of AnalysisApr 19, 2024 Ab121011
ZJ24F0404687Certificate of AnalysisApr 19, 2024 Ab121011
ZJ24F0404686Certificate of AnalysisApr 19, 2024 Ab121011

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