PD0325901 - ≥99%, high purity , Dual specificity mitogen-activated protein kinase kinase 2 inhibitor, CAS No.391210-10-9, Dual specificity mitogen-activated protein kinase kinase 2 inhibitor

Item Number

P125494

• Synonyms: 391210-10-9|PD0325901|PD 0325901|Mirdametinib|PD-0325901|(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide|PD-325901|(R)-N-(2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOPHENYLAMINO)BENZAMIDE|N-[(2R)-2,3-dihydroxyp
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: Potent MEK1 and MEK2 inhibitor. Inhibits MEK activity in mouse colon 26 cells (IC50= 0.33 nM). Inhibits the growth of melanoma cell linesin vitroandin vivo; induces G1-phase cell cycle arrest and apoptosis in a mouse xenograft model. Also inhibits produc
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
• Note: 25mg、100mg卖完停产，不再备货

Product Description

PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2.
An inhibitor of MEK and suppressor of ERK phosphorylation