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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P129377-1mg | 1mg | In stock | $36.90 | |
P129377-5mg | 5mg | In stock | $139.90 | |
P129377-10mg | 10mg | In stock | $251.90 | |
P129377-25mg | 25mg | In stock | $442.90 | |
P129377-50mg | 50mg | In stock | $796.90 | |
P129377-100mg | 100mg | In stock | $1,434.90 |
Synonyms | A13201 | PD123319 | PD-123319 | (6S)-1-[(4-dimethylamino-3-methylphenyl)methyl]-5-[2,2-di(phenyl)acetyl]-6,7-dihydro-4H-imidazo[5,4-d]pyridine-6-carboxylic acid | BDBM50282396 | (6s)1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-t |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | PD 123319 is shown to discriminate between two subclasses of AII receptors in many different tissues. 125I-AII specifically label two classes of binding sites for AII in a membrane preparation of bovine adrenal glomerulosa cells. The first class (DuP-753 |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of AT 2 receptor |
Product Description | product description: PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | (6S)-1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid |
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INCHI | InChI=1S/C31H32N4O3/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38)/t28-/m0/s1 |
InChi Key | YSTVFDAKLDMYCR-NDEPHWFRSA-N |
Canonical SMILES | CC1=C(C=CC(=C1)CN2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C |
Isomeric SMILES | CC1=C(C=CC(=C1)CN2C=NC3=C2C[C@H](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C |
PubChem CID | 5311345 |
Molecular Weight | 508.61 |
PubChem CID | 5311345 |
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ChEBI | CHEBI:61014 |
ChEMBL Ligand | CHEMBL321820 |
BindingDB Ligand | 50010338 |
CAS Registry No. | 130663-39-7 |
GPCRdb Ligand | PD123319 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2312328 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312329 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312334 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312335 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312338 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312341 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312343 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312344 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312345 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312349 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2312352 | Certificate of Analysis | Jun 17, 2023 | P129377 |
H2314339 | Certificate of Analysis | Jun 17, 2023 | P129377 |
Solubility | DMSO 100 mg/mL Water 100 mg/mL Ethanol 100 mg/mL |
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Starting at $241.90