PD123319 - 10mM in DMSO, high purity , CAS No.130663-39-7

Item Number
P421190
Grouped product items
SKUSizeAvailabilityPrice Qty
P421190-1ml
1ml
Available within 8-12 weeks(?)
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$241.90

Basic Description

SynonymsPD123319 | 130663-39-7 | PD 123319 | PD-123319 | CHEBI:61014 | (6S)-1-[4-(dimethylamino)-3-methylbenzyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid | 1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphe
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms

Description:
IC50 Value:  1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]
PD 123319 is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 n

Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets(Human)

AGTR1 Tclin Type-1 angiotensin II receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (6S)-1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid
INCHI InChI=1S/C31H32N4O3/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38)/t28-/m0/s1
InChi Key YSTVFDAKLDMYCR-NDEPHWFRSA-N
Canonical SMILES CC1=C(C=CC(=C1)CN2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C
Isomeric SMILES CC1=C(C=CC(=C1)CN2C=NC3=C2C[C@H](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C
PubChem CID 5311345
Molecular Weight 508.61

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