Pefloxacin - 98%, high purity , Topoisomerase IV inhibitor, CAS No.70458-92-3, Topoisomerase IV inhibitor

Item Number
P304448
Grouped product items
SKUSizeAvailabilityPrice Qty
P304448-10mg
10mg
In stock
$19.90
P304448-25mg
25mg
In stock
$40.90
P304448-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$135.90
P304448-250mg
250mg
In stock
$304.90
P304448-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,095.90
View related series
Anti-infection Antibiotic

Basic Description

Synonyms1584RB | 1589-RB | Pefloxacin [USAN:INN:BAN] | SBI-0206758.P001 | SMR000273037 | D02306 | Oprea1_063677 | 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-methylpiperazinyl)quinoline-3-
Specifications & PurityMoligand™, ≥98%
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionTopoisomerase IV inhibitor

Product Properties

ALogP0.3

Associated Targets(Human)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

gyrB DNA gyrase subunit B (290 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii yoelii (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Providencia rettgeri (925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus hominis (482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella aerogenes (4963 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Serratia marcescens (3237 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pyogenes (16140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
V79 (1637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
gyrB DNA gyrase (2092 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium leprae (477 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
INCHI InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)
InChi Key FHFYDNQZQSQIAI-UHFFFAOYSA-N
Canonical SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
Isomeric SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
PubChem CID 51081
Molecular Weight 333.36

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
L2103270Certificate of AnalysisSep 19, 2024 P304448
L2103271Certificate of AnalysisSep 19, 2024 P304448
L2103329Certificate of AnalysisSep 19, 2024 P304448
L2103330Certificate of AnalysisSep 19, 2024 P304448
L2304031Certificate of AnalysisNov 08, 2021 P304448

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Citations of This Product

1. Yanzhuo Zhang, Yutai Sun, Rui He, Jing Zhao, Jiqin Wang, Tonghuan Yu, Xiaozhuan Zhang, Alexandr V. Bildyukevich.  (2024)  Effects of excess sludge composting process, environmentally persistent free radicals, and microplastics on antibiotics degradation efficiency of aging biochar.  BIORESOURCE TECHNOLOGY,  393  (15): (130070).  [PMID:37984667] [10.1016/j.biortech.2023.130070]
2. Xuan Wan, Haohao Du, Du Tuo, Xiaoman Qi, Tianyu Wang, Jingtao Wu, Guangli Li.  (2023)  UiO-66/Carboxylated Multiwalled Carbon Nanotube Composites for Highly Efficient and Stable Voltammetric Sensors for Gatifloxacin.  ACS Applied Nano Materials,  (20): (19403–19413).  [PMID:15378032] [10.1021/acsanm.3c03874]
3. Guangli Li, Xuan Wan, Yonghui Xia, Du Tuo, Xiaoman Qi, Tianyu Wang, Mohammad Mehmandoust, Nevin Erk, Quanguo He, Qing Li.  (2023)  Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin.  ACS Applied Nano Materials,  (18): (17040–17052).  [PMID:11485546] [10.1021/acsanm.3c03162]
4. Han Yin, Ziyi Zhen, Weijie Ning, Lu Zhang, Yuhong Xiang, Nengsheng Ye.  (2023)  Three-dimensional fluorinated covalent organic frameworks coated capillary for the separation of fluoroquinolones by capillary electrochromatography.  JOURNAL OF CHROMATOGRAPHY A,  1706  (464234).  [PMID:37523908] [10.1016/j.chroma.2023.464234]
5. L. Wang, D. Wang, Y. Tao, J. Wang, M. Tian, Q. Liu, Y. Yang, Y. Zou, F. Ke, X. Guo, X. Li, D. Gao.  (2023)  Phenylboronic acid functionalized high-crystallinity fluorescent covalent organic framework act as a sensing platform with dual performance for rifamycin antibiotics and water and adsorbent for rifamycin antibiotics.  Materials Today Chemistry,  32  (101647).  [PMID:] [10.1016/j.mtchem.2023.101647]
6. Chang Liu, Hong Lin, Limin Cao, Kaiqiang Wang, Jianxin Sui.  (2023)  Characterization, specific recognition, and the performance in fish matrix of a shark-derived single-domain antibody against enrofloxacin.  TALANTA,  265  (124852).  [PMID:37385191] [10.1016/j.talanta.2023.124852]
7. Changxing Wang, Feifei Qin, Siyuan Tang, Xiameng Li, Tingting Li, Guoqiang Guo, Chenjie Gu, Xu Wang, Da Chen.  (2023)  Construction of graphene quantum dots ratiometric fluorescent probe by intermolecular electron transfer effect for intelligent and real-time visual detection of ofloxacin and its L-isomer in daily drink.  FOOD CHEMISTRY,  411  (135514).  [PMID:36724609] [10.1016/j.foodchem.2023.135514]
8. Rong Shen, Yichang Yu, Qinfang Liu, Ruili Wang, Rong Lan, Hui Feng, Ran Yu, Lihua Jin, Ye Li.  (2022)  Toxic Effects and Mechanism of Pefloxacin on the Early Life Stage of Zebrafish (Danio rerio).  Water,  14  (23): (3857).  [PMID:] [10.3390/w14233857]
9. Ruizhen Li, Yu Hu, Lijun Du, Jiawen Li, Jigang Yuan, Xingyong Liu.  (2022)  In-situ photoelectrocatalytical formation of sulfate radicals on BiPO4 modified carbon paper electrode in sodium sulfate electrolyte for high efficient degradation of pefloxacin.  JOURNAL OF MOLECULAR STRUCTURE,  1268  (133547).  [PMID:] [10.1016/j.molstruc.2022.133547]
10. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin.  (2022)  The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics.  MOLECULAR & CELLULAR PROTEOMICS,  21  (9):   [PMID:35605723] [10.1016/j.mcpro.2022.100248]
11. Jin'ai Chen, Yuting Jin, Taotao Ren, Shuo Wang, Xianghong Wang, Fuyuan Zhang, Yiwei Tang.  (2022)  A novel terbium (III) and aptamer-based probe for label-free detection of three fluoroquinolones in honey and water samples.  FOOD CHEMISTRY,  386  (132751).  [PMID:35334319] [10.1016/j.foodchem.2022.132751]
12. Huang Hongli, Zheng Yongxin, Wei Dongning, Yang Guang, Peng Xin, Fan Lingjia, Luo Lin, Zhou Yaoyu.  (2022)  Efficient removal of pefloxacin from aqueous solution by acid–alkali modified sludge-based biochar: adsorption kinetics, isotherm, thermodynamics, and mechanism.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  29  (28): (43201-43211).  [PMID:35091955] [10.1007/s11356-021-18220-9]
13. Yanzhuo Zhang, Mengqi Xu, Rui He, Jing Zhao, Wei Kang, Jinghua Lv.  (2022)  Effect of pyrolysis temperature on the activated permonosulfate degradation of antibiotics in nitrogen and sulfur-doping biochar: Key role of environmentally persistent free radicals.  CHEMOSPHERE,  294  (133737).  [PMID:35090846] [10.1016/j.chemosphere.2022.133737]
14. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen.  (2021)  Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner.  Foods,  10  (8): (1838).  [PMID:34441616] [10.3390/foods10081838]
15. Yukun Huang, Chong Wang, Qiming Wei, Yaning Song, Pengfei Chen, Lijun Wang, Xiao Yang, Xianggui Chen.  (2021)  A sensitive aptasensor based on rolling circle amplification and G-rich ssDNA/terbium (III) luminescence enhancement for ofloxacin detection in food.  TALANTA,  235  (122783).  [PMID:34517641] [10.1016/j.talanta.2021.122783]
16. Cuizhu Ye, Xingguang Chen, Dong Zhang, Junjun Xu, Huiting Xi, Tiantian Wu, Danwen Deng, Chunhong Xiong, Jinsheng Zhang, Ganhui Huang.  (2021)  Study on the properties and reaction mechanism of polypyrrole@norfloxacin molecularly imprinted electrochemical sensor based on three-dimensional CoFe-MOFs/AuNPs.  ELECTROCHIMICA ACTA,  379  (138174).  [PMID:] [10.1016/j.electacta.2021.138174]
17. Xiangning Han, Hong Lin, Limin Cao, Xiangfeng Chen, Luefeng Wang, Hongwei Zheng, Ziang Zhang, Tushar Ramesh Pavase, Sai Wang, Xun Sun, Jianxin Sui.  (2020)  Hapten-Branched Polyethylenimine as a New Antigen Affinity Ligand to Purify Antibodies with High Efficiency and Specificity.  ACS Applied Materials & Interfaces,  12  (52): (58191–58200).  [PMID:33319977] [10.1021/acsami.0c15586]
18. Chun Yang, Rui Li, Qi Wang, Wenhao Wang, Pei Gao, Bibo Hu.  (2021)  Synthesis of alkyl-functionalized magnetic for fluoroquinolones removal: Adsorption performance and mechanism studies in single and binary systems.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  608  (125549).  [PMID:] [10.1016/j.colsurfa.2020.125549]
19. Zhenping Liu, Mingliang Jin, Han Lu, Jiyuan Yao, Xin Wang, Guofu Zhou, Lingling Shui.  (2019)  Molecularly imprinted polymer decorated 3D-framework of functionalized multi-walled carbon nanotubes for ultrasensitive electrochemical sensing of Norfloxacin in pharmaceutical formulations and rat plasma.  SENSORS AND ACTUATORS B-CHEMICAL,  288  (363).  [PMID:] [10.1016/j.snb.2019.02.097]
20. Hua Jianhao, Jiao Yang, Wang Meng, Yang Yaling.  (2018)  Determination of norfloxacin or ciprofloxacin by carbon dots fluorescence enhancement using magnetic nanoparticles as adsorbent.  MICROCHIMICA ACTA,  185  (2): (1-9).  [PMID:29594473] [10.1007/s00604-018-2685-x]
21. Dan Liu, Jiutong Ma, Yan Jin, Xiqian Li, Xiao Zhou, Qiong Jia, Weihong Zhou.  (2014)  Preparation of a monolith functionalized with zinc oxide nanoparticles and its application in the enrichment of fluoroquinolone antibiotics.  JOURNAL OF SEPARATION SCIENCE,  38  (1): (134-140).  [PMID:25354394] [10.1002/jssc.201400893]
22. Wenying Fan,Man He,Xiaoran Wu,Beibei Chen,Bin Hu.  (2015-10-05)  Graphene oxide/polyethyleneglycol composite coated stir bar for sorptive extraction of fluoroquinolones from chicken muscle and liver..  Journal of chromatography. A,  1418  (36-44).  [PMID:26433263]

References

1. Yourassowsky E, Van der Linden MP, Crokaert F, Glupczynski Y.  (1986)  In-vitro activity of pefloxacin compared to other antibiotics..  J Antimicrob Chemother,  17 Suppl B  (13): (19-28).  [PMID:3086279] [10.1021/op500134e]
2. Yanzhuo Zhang, Yutai Sun, Rui He, Jing Zhao, Jiqin Wang, Tonghuan Yu, Xiaozhuan Zhang, Alexandr V. Bildyukevich.  (2024)  Effects of excess sludge composting process, environmentally persistent free radicals, and microplastics on antibiotics degradation efficiency of aging biochar.  BIORESOURCE TECHNOLOGY,  393  (15): (130070).  [PMID:37984667] [10.1016/j.biortech.2023.130070]
3. Xuan Wan, Haohao Du, Du Tuo, Xiaoman Qi, Tianyu Wang, Jingtao Wu, Guangli Li.  (2023)  UiO-66/Carboxylated Multiwalled Carbon Nanotube Composites for Highly Efficient and Stable Voltammetric Sensors for Gatifloxacin.  ACS Applied Nano Materials,  (20): (19403–19413).  [PMID:15378032] [10.1021/acsanm.3c03874]
4. Guangli Li, Xuan Wan, Yonghui Xia, Du Tuo, Xiaoman Qi, Tianyu Wang, Mohammad Mehmandoust, Nevin Erk, Quanguo He, Qing Li.  (2023)  Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin.  ACS Applied Nano Materials,  (18): (17040–17052).  [PMID:11485546] [10.1021/acsanm.3c03162]
5. Han Yin, Ziyi Zhen, Weijie Ning, Lu Zhang, Yuhong Xiang, Nengsheng Ye.  (2023)  Three-dimensional fluorinated covalent organic frameworks coated capillary for the separation of fluoroquinolones by capillary electrochromatography.  JOURNAL OF CHROMATOGRAPHY A,  1706  (464234).  [PMID:37523908] [10.1016/j.chroma.2023.464234]
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Solution Calculators