Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P160772-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $14.90 | |
P160772-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $34.90 | |
P160772-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $153.90 | |
P160772-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $687.90 |
D 2 receptor antagonist. T-type Ca 2+ channel blocker.
Synonyms | PENFLURIDOL | 26864-56-2 | Semap | 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol | Penfluridolum | McN-JR-16,341 | TLP-607 | R-16341 | Micefal | 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol | 1- |
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Specifications & Purity | ≥97%(HPLC) |
Biochemical and Physiological Mechanisms | T-type Ca2+ channel blocker.D 2 receptor antagonist. T-type Ca 2+ channel blocker. Increases BDNF levels in astrocytes. Shows antiproliferative effects. Shows antitumor and long acting antipsychotic effects in vivo. Orally active. Blood-brain barrier perm |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Penfluridol is a highly potent, first generation diphenylbutylpiperidine antipsychotic. |
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IUPAC Name | 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol |
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INCHI | InChI=1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2 |
InChi Key | MDLAAYDRRZXJIF-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F |
Isomeric SMILES | C1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F |
WGK Germany | 3 |
RTECS | TN6957000 |
PubChem CID | 33630 |
Molecular Weight | 523.97 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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D2323264 | Certificate of Analysis | Sep 28, 2022 | P160772 |
D2323265 | Certificate of Analysis | Sep 28, 2022 | P160772 |
D2323266 | Certificate of Analysis | Sep 28, 2022 | P160772 |
D2323267 | Certificate of Analysis | Sep 28, 2022 | P160772 |
Solubility | Solubility in water: Practically insoluble |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 108 °C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | TN6957000 |
Merck Index | 7087 |