Peroxiredoxin 2/PRP Mouse mAb - Primary antibody, specific to Peroxiredoxin 2/PRP, Mouse IgG1

Features and benefits
  • Short Overview:

    mAb (C2); Mouse anti Human Peroxiredoxin 2/PRP Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Mouse IgG1
    Application:
  • WB
Item Number
Ab121321
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab121321-10μl
10μl
In stock
$69.90
Ab121321-50μl
50μl
In stock
$199.90
Ab121321-100μl
100μl
In stock
$289.90
Ab121321-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

mAb (C2); Mouse anti Human Peroxiredoxin 2/PRP Antibody; WB; Unconjugated

Basic Description

Product NamePeroxiredoxin 2/PRP Mouse mAb - Primary antibody, specific to Peroxiredoxin 2/PRP, Mouse IgG1
SynonymsHEL-S-2a | NKEF-B | NKEFB | PRP | PRX2 | PRXII | PTX1 | TDPX1 | TPX1 | TSA | EC 1.11.1 | MGC4104 | Natural killer cell-enhancing factor B | natural killer-enhancing factor B | NKEFBNKEF-B | Peroxiredoxin 2 | peroxiredoxin-2 | PRDX2 | PRPTDPX1 | thiol-spec
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot
Host speciesMouse
SpecificityPeroxiredoxin 2/PRP
ImmunogenRecombinant PRDX2 expressed in E.coli (AA 2-198)
Positive ControlWB: SK-N-SH, HeLa, HEK293, MCF7, LNCaP and NIH/3T3 cell lysates.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, High Performance, Validated
Product Description

Mouse anti Human Peroxiredoxin 2/PRP Antibody, Monoclonal (C2), could be used for WB and so on.
Application:
WB: 0.01-2µg/mL
Protein Function
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).

Product Properties

IsotypeMouse IgG1
SDS-PAGE150 kDa
Purification MethodProtein A + Protein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Peroxiredoxin 2/PRP Mouse mAb (Ab121321) - Western Blot
All lanes: Peroxiredoxin 2/PRP Mouse mAb (Ab121321) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 22 kDa
Observed band size: 22 kDa
Exposure time: 11.3 s

Associated Targets(Human)

PRDX2 Tbio Peroxiredoxin-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PRDX2 Tbio Peroxiredoxin-2 (16 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Application

ApplicationDilution info
WB

0.01-2 µg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404486Certificate of AnalysisApr 12, 2024 Ab121321
ZJ24F0404485Certificate of AnalysisApr 12, 2024 Ab121321
ZJ24F0404484Certificate of AnalysisApr 12, 2024 Ab121321

Related Documents

References

1. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed.  (2009-05-06)  Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach..  Analytical chemistry,  81  ((11)): (4493-4501).  [PMID:19413330]
2. Rasmussen, H H HH and 5 more authors..  (1992)  Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes..  Electrophoresis,      [PMID:1286667]
3. Shau, H H, Butterfield, L H LH, Chiu, R R and Kim, A A..  (1994)  Cloning and sequence analysis of candidate human natural killer-enhancing factor genes..  Immunogenetics,      [PMID:8026862]
4. Lim, Y S YS, Cha, M K MK, Kim, H K HK and Kim, I H IH..  (1994)  The thiol-specific antioxidant protein from human brain: gene cloning and analysis of conserved cysteine regions..  Gene,    (25):   [PMID:8144038]
5. Golaz, O O and 9 more authors..  (1993)  Plasma and red blood cell protein maps: update 1993..  Electrophoresis,      [PMID:8313871]
6. Cha, M K MK and Kim, I H IH..  (1995)  Thioredoxin-linked peroxidase from human red blood cell: evidence for the existence of thioredoxin and thioredoxin reductase in human red blood cell..  Biochemical and biophysical research communications,    (26):   [PMID:8554614]
7. Ji, H H and 5 more authors..  ()  A two-dimensional gel database of human colon carcinoma proteins..  Electrophoresis,      [PMID:9150948]
8. Schröder, E E and 5 more authors..  (2000)  Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7 A resolution..  Structure (London, England : 1993),    (15):   [PMID:10873855]
9. Rabilloud, Thierry T and 8 more authors..  (2002)  Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site..  The Journal of biological chemistry,    (31):   [PMID:11904290]
10. Chevallet, Mireille M and 5 more authors..  (2003)  Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress..  The Journal of biological chemistry,    (26):   [PMID:12853451]
11. Andersen, Jens S JS and 5 more authors..  (2003)  Proteomic characterization of the human centrosome by protein correlation profiling..  Nature,    (4):   [PMID:14654843]
12. Gotter, Anthony L AL, Suppa, Christine C and Emanuel, Beverly S BS..  (2007)  Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors..  Journal of molecular biology,    (9):   [PMID:17141802]
13. Rosenow, Anja A and 6 more authors..  (2012)  Resveratrol-induced changes of the human adipocyte secretion profile..  Journal of proteome research,    (7):   [PMID:22905912]
14. Kamariah, Neelagandan; Sek, Mun Foong; Eisenhaber, Birgit; Eisenhaber, Frank and Grüber, Gerhard..  (2016)  Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins..  Scientific reports,    (28):   [PMID:27892488]

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