Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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P424887-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
Synonyms | perphenazine | 58-39-9 | Trilafon | Perphenazin | Etaperazine | Perfenazine | Ethaperazine | Etaperazin | Fentazin | Chlorpiprazine | Decentan | Perphenan | Thilatazin | Chlorperphenazine | Perfenazina | Tranquisan | Triphenot | Emesinal | Trifaron | Trilifan | F-mon | Perphenazinum | 2-(4-(3-(2-Ch |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Perphenazine is an antipsychotic drug used in treating schizophrenia. It modulates antioxidant levels and helps in the management of oxidative injury in schizophrenia. However, it is less effective than the clozapine drug group in improving response to oxidative injury. |
ALogP | 4.2 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol |
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INCHI | InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 |
InChi Key | RGCVKNLCSQQDEP-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO |
Isomeric SMILES | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO |
WGK Germany | 3 |
RTECS | TL7175000 |
PubChem CID | 4748 |
Molecular Weight | 403.97 |
Reaxy-Rn | 54730 |
Enter Lot Number to search for COA:
Sensitivity | Heat & Light Sensitive |
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Melt Point(°C) | 97 °C |
Pictogram(s) | GHS06, GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H330:Fatal if inhaled H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P316:Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | TL7175000 |
Reaxy-Rn | 54730 |
Merck Index | 7183 |
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |
2. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang. (2023) Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2599-2608). [PMID:] |
3. Yuanhui Chong, Qiong Liu, Zeqi Wang, Liukai Zhu, Fengxin Guo, Yu Li, Tao Li, Baozeng Ren. (2022) Solubility, MD simulation, thermodynamic properties and solvent effect of perphenazine (Form I) in eleven neat organic solvents ranged from 278.15 K to 318.15 K. JOURNAL OF MOLECULAR LIQUIDS, 348 (118184). [PMID:] |
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |
2. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang. (2023) Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (5): (2599-2608). [PMID:] |
3. Yuanhui Chong, Qiong Liu, Zeqi Wang, Liukai Zhu, Fengxin Guo, Yu Li, Tao Li, Baozeng Ren. (2022) Solubility, MD simulation, thermodynamic properties and solvent effect of perphenazine (Form I) in eleven neat organic solvents ranged from 278.15 K to 318.15 K. JOURNAL OF MOLECULAR LIQUIDS, 348 (118184). [PMID:] |