PF-04217903 - ≥98%, high purity , Hepatocyte growth factor receptor inhibitor, CAS No.956905-27-4, Hepatocyte growth factor receptor inhibitor

Item Number

P127567

Grouped product items
SKU	Size	Availability	Price
P127567-2mg	2mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$45.90
P127567-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$90.90
P127567-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$142.90
P127567-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$430.90

Basic Description

Synonyms	PF-04217903\|956905-27-4\|PF04217903\|1159490-85-3\|2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol\|PF 04217903\|PF-4217903\|CYJ9ATV1IJ\|Met tyrosine kinase inhibitor PF-04217903\|CHEMBL2001019\|2-[4-[3-(quinolin-6-ylme
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Action Type	INHIBITOR
Mechanism of action	Hepatocyte growth factor receptor inhibitor
Product Description	PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant). A selective ATP-competitive Met inhibitor.

Names and Identifiers

IUPAC Name	2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
INCHI	InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
InChi Key	PDMUGYOXRHVNMO-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
Isomeric SMILES	C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
PubChem CID	17754438
Molecular Weight	372.38

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Basic Description