PF-04929113 (SNX-5422) - ≥98%, high purity , Heat shock protein HSP90 inhibitor, CAS No.908115-27-5, Heat shock protein HSP90 inhibitor

Item Number

P126273

• Synonyms: SNX-5422 | 908115-27-5 | PF-04929113 | PF-4929113 | SNX 5422 | PF-04929113 (SNX-5422) | PF-04929113 free base | PF 04929113 | BF52J69Q8T | PF04929113 | SNX5422 | 908115-27-5 (free base) | (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-ind
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: PF-04929113 (SNX-5422) is a potent and selective Hsp90 inhibitor (Kd of 41 nM). PF-04929113 also inhibits Her-2 degradation (IC50 of 37 nM). PF-04929113 is a small-molecule Hsp90 inhibitor based on the 6,7-dihydro-indazol-4-one scaffold. PF-04929113 exhib
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Action Type: INHIBITOR
• Mechanism of action: Heat shock protein HSP90 inhibitor
• Note: Toxic, refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.